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Molecular Reproduction and Development,Volume 85, Issue 3, Page 188-196, March 2018. (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - February 5, 2018 Category: Reproduction Medicine Source Type: research

Inhibition of Dr ‐dut gene causes DNA damage in planarian
This study aimed to investigate the role of Dr‐dut gene in the planarian Dugesia ryukyuensis by assessing the consequences of Dr‐dut silencing on known phenomena, including regeneration following amputation and radiation damage. We functionally disrupted planarian Dr‐dut mRNA by feeding RNAi‐containing food to animals. Dr‐dut RNAi resulted in the death of planarians in 28 days, and elevated double‐stranded DNA breakage. Expression of the DNA damage response gene Dr‐atm and the DNA repair genes Dr‐rad51 and Dr‐rad51c temporarily increased, and then decreased following the onset of feeding. When RNAi‐trea...
Source: Molecular Reproduction and Development - February 5, 2018 Category: Reproduction Medicine Authors: Md. Shahanoor Alam, Hideaki Moriyama, Midori Matsumoto Tags: RESEARCH ARTICLE Source Type: research

Paternal age: Negative impact on sperm genome decays and IVF outcomes after 40 years
Molecular Reproduction and Development,Volume 85, Issue 3, Page 271-280, March 2018. (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - February 2, 2018 Category: Reproduction Medicine Source Type: research

Regionally distinct patterns of STAT3 phosphorylation in the seminiferous epithelia of mouse testes
Molecular Reproduction and Development,Volume 85, Issue 3, Page 262-270, March 2018. (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - February 2, 2018 Category: Reproduction Medicine Source Type: research

TALEN ‐mediated gene targeting in porcine spermatogonia
Molecular Reproduction and Development,Volume 85, Issue 3, Page 250-261, March 2018. (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - February 2, 2018 Category: Reproduction Medicine Source Type: research

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Molecular Reproduction and Development,Volume 85, Issue 3, Page 271-280, March 2018. (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - February 2, 2018 Category: Reproduction Medicine Source Type: research

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Molecular Reproduction and Development,Volume 85, Issue 3, Page 262-270, March 2018. (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - February 2, 2018 Category: Reproduction Medicine Source Type: research

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Molecular Reproduction and Development,Volume 85, Issue 3, Page 250-261, March 2018. (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - February 2, 2018 Category: Reproduction Medicine Source Type: research

Hyperglycemia ‐induced mouse trophoblast spreading is mediated by reactive oxygen species
This study evaluated the role of reactive oxygen species (ROS) in the actions of high glucose concentration (HG) on trophoblast spreading and the expression of extracellular proteases in cultured mouse conceptuses. Blastocysts from gestational day 4 (GD4) were cultured until GD7 in HAM‐F10 medium and further treated for 48 h with HG (25 mM glucose) from GD7 to GD9. This treatment induced larger trophoblast outgrowths and increased ROS concentration, which was associated with increased expression levels of urokinase‐type plasminogen activator (PLAU), plasminogen activator inhibitor 1 (PAI‐1) and matrix metalloprot...
Source: Molecular Reproduction and Development - February 2, 2018 Category: Reproduction Medicine Authors: S ánchez‐Santos A, Martínez‐Hernández MG, Contreras‐Ramos A, Ortega‐Camarillo C, Baiza‐Gutman LA Tags: RESEARCH ARTICLE Source Type: research

Activated receptor tyrosine kinases in granulosa cells of ovulating follicles in mice
This article is protected by copyright. All rights reserved (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - February 2, 2018 Category: Reproduction Medicine Authors: Yasmin Schuermann, Dayananda Siddappa, Melissa Pansera, Raj Duggavathi Tags: RESEARCH ARTICLE Source Type: research

Paternal age: Negative impact on sperm genome decays and IVF outcomes after 40 years
This study assessed sperm quality declining on relation to paternal age and its impact on in vitro fertilization (IVF) outcomes in order to estimate the APA (Advanced Paternal Age) cutoff. For this, 83 couples undergoing IVF treatment for male factor infertility were enrolled. The women age was ≤39 years, whereas the men were divided in two groups: APA (n = 41; age≥40 years) and young (Y) (n = 42; age < 40 years). Conventional semen parameters (volume, concentration, motility, vitality and morphology) were analyzed in the collected sperm samples. Furthermore, sperm genome decays (SGD) was assessed by TUN...
Source: Molecular Reproduction and Development - February 2, 2018 Category: Reproduction Medicine Authors: ISMAIL KAAROUCH, NOUZHA BOUAMOUD, AICHA MADKOUR, NOUREDDINE LOUANJLI, BRAHIM SAADANI, SAID ASSOU, SMAHANE ABOULMAOUAHIB, SAAID AMZAZI, HENRI COPIN, MONCEF BENKHALIFA, SEFRIOUI OMAR Tags: RESEARCH ARTICLE Source Type: research

Pharmacologic treatment of donor cells induced to have a Warburg Effect ‐like metabolism does not alter embryonic development in vitro or survival during early gestation when used in somatic cell nuclear transfer in pigs
This article is protected by copyright. All rights reserved (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - February 2, 2018 Category: Reproduction Medicine Authors: B. R. Mordhorst, S. L. Murphy, R. M. Ross, J. A. Benne, M. S. Samuel, R. F. Cecil, B. K. Redel, L. D. Spate, C. N. Murphy, K. D. Wells, J. A. Green, R. S. Prather Tags: RESEARCH ARTICLE Source Type: research

Regionally Distinct Patterns of STAT3 Phosphorylation in the Seminiferous Epithelia of Mouse Testes
This article is protected by copyright. All rights reserved (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - February 2, 2018 Category: Reproduction Medicine Authors: Keiya Nagasawa, Kasane Imura ‐Kishi, Aya Uchida, Ryuji Hiramatsu, Masamichi Kurohmaru, Yoshiakira Kanai Tags: RESEARCH ARTICLE Source Type: research

TALEN ‐Mediated Gene Targeting in Porcine Spermatogonia
This article is protected by copyright. All rights reserved (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - February 2, 2018 Category: Reproduction Medicine Authors: Lin Tang, Alla Bondareva, Raquel Gonz ález, Jose Rafael Rodriguez‐Sosa, Daniel F. Carlson, Dennis Webster, Scott Fahrenkrug, Ina Dobrinski Tags: RESEARCH ARTICLE Source Type: research

Neonatal respiratory distress syndrome and underlying mechanisms in cloned cattle
Molecular Reproduction and Development,Volume 85, Issue 3, Page 227-235, March 2018. (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - February 1, 2018 Category: Reproduction Medicine Source Type: research