Hydrogen sulfide provides cardioprotection against myocardial/ischemia reperfusion injury in the diabetic state through the activation of the RISK pathway
Conclusion
These findings provide important information that myocardial Erk1/2 activation by Na2S therapy following MI/R sets into motion events, which ultimately lead to cardioprotection in the setting of diabetes. (Source: Medical Gas Research)
Source: Medical Gas Research - December 12, 2014 Category: Biomedical Science Source Type: research
Hyperbaric oxygen therapy applied research in traumatic brain injury: from mechanisms to clinical investigation
AbstractTraumatic brain injury (TBI) is the leading cause of mortality and morbidity for millions of young people and military personnel around the world every year. Regardless of severity, neurological dysfunction is a sequela of TBI. Although many preclinical and clinical trials have been carried out to explore its underlying pathophysiology, few effective treatment options have been used to ameliorate the prognosis of TBI, particularly with regard to the recovery of neurological deficits. Translational medicine has increasingly emphasized secondary brain injury, as distinguished from the mechanical damage occurring at t...
Source: Medical Gas Research - December 4, 2014 Category: Biomedical Science Source Type: research
Hyperbaric oxygen therapy applied research in traumatic brain injury: from mechanisms to clinical investigation
Abstract
Traumatic brain injury (TBI) is the leading cause of mortality and morbidity for millions of young people and military personnel around the world every year. Regardless of severity, neurological dysfunction is a sequela of TBI. Although many preclinical and clinical trials have been carried out to explore its underlying pathophysiology, few effective treatment options have been used to ameliorate the prognosis of TBI, particularly with regard to the recovery of neurological deficits. Translational medicine has increasingly emphasized secondary brain injury, as distinguished from the mechanical ...
Source: Medical Gas Research - December 4, 2014 Category: Biomedical Science Source Type: research
Review and prospect of the biomedical effects of hydrogen
In conclusion, this review might be a reference and guidance for relative scholars. (Source: Medical Gas Research)
Source: Medical Gas Research - November 29, 2014 Category: Biomedical Science Source Type: research
Review and prospect of the biomedical effects of hydrogen
In conclusion, this review might be a reference and guidance for relative scholars. (Source: Medical Gas Research)
Source: Medical Gas Research - November 29, 2014 Category: Biomedical Science Source Type: research
A review of experimental studies of hydrogen as a new therapeutic agent in emergency and critical care medicine
AbstractHydrogen is the most abundant chemical element in the Universe, but is seldom regarded as a therapeutic agent. Recent evidence has shown that hydrogen is a potent antioxidative, antiapoptotic and anti-inflammatory agent and so may have potential medical applications in cells, tissues and organs. There are several methods to administer hydrogen, such as inhalation of hydrogen gas, aerosol inhalation of a hydrogen-rich solution, drinking hydrogen dissolved in water, injecting hydrogen-rich saline (HRS) and taking a hydrogen bath. Drinking hydrogen solution (saline/pure water/other solutions saturated with hydrogen) m...
Source: Medical Gas Research - November 8, 2014 Category: Biomedical Science Source Type: research
A review of experimental studies of hydrogen as a new therapeutic agent in emergency and critical care medicine
Abstract
Hydrogen is the most abundant chemical element in the Universe, but is seldom regarded as a therapeutic agent. Recent evidence has shown that hydrogen is a potent antioxidative, antiapoptotic and anti-inflammatory agent and so may have potential medical applications in cells, tissues and organs. There are several methods to administer hydrogen, such as inhalation of hydrogen gas, aerosol inhalation of a hydrogen-rich solution, drinking hydrogen dissolved in water, injecting hydrogen-rich saline (HRS) and taking a hydrogen bath. Drinking hydrogen solution (saline/pure water/other solutions satur...
Source: Medical Gas Research - November 8, 2014 Category: Biomedical Science Source Type: research
Supplemental oxygen delivery to suspected stroke patients in pre hospital and emergency department settings
ConclusionsSuspected stroke patients routinely receive 10 –15 L/min oxygen in the ambulance however in the ED there is wide variability due to factors such as clinical severity. Oxygen delivery appears safe in the PH and ED settings. (Source: Medical Gas Research)
Source: Medical Gas Research - October 27, 2014 Category: Biomedical Science Source Type: research
Supplemental oxygen delivery to suspected stroke patients in pre hospital and emergency department settings
Conclusions
Suspected stroke patients routinely receive 10–15 L/min oxygen in the ambulance however in the ED there is wide variability due to factors such as clinical severity. Oxygen delivery appears safe in the PH and ED settings. (Source: Medical Gas Research)
Source: Medical Gas Research - October 27, 2014 Category: Biomedical Science Source Type: research
Progress in the study of biological effects of hydrogen on higher plants and its promising application in agriculture
AbstractWhile the medical effects of hydrogen have been broadly analyzed, research into the effects of hydrogen on higher plants has often been of lesser concern. Recent studies on the botanical effects of hydrogen have shown that it is involved in signal transduction pathways of plant hormones and can improve the resistance of plants to stressors, such as drought, salinity, cold and heavy metals. In addition, hydrogen could delay postharvest ripening and senescence of fruits. Observational evidence has also shown that hydrogen can regulate the flowering time of plants. These results indicate that hydrogen may have great p...
Source: Medical Gas Research - August 20, 2014 Category: Biomedical Science Source Type: research
Progress in the study of biological effects of hydrogen on higher plants and its promising application in agriculture
Abstract
While the medical effects of hydrogen have been broadly analyzed, research into the effects of hydrogen on higher plants has often been of lesser concern. Recent studies on the botanical effects of hydrogen have shown that it is involved in signal transduction pathways of plant hormones and can improve the resistance of plants to stressors, such as drought, salinity, cold and heavy metals. In addition, hydrogen could delay postharvest ripening and senescence of fruits. Observational evidence has also shown that hydrogen can regulate the flowering time of plants. These results indicate that hydr...
Source: Medical Gas Research - August 20, 2014 Category: Biomedical Science Source Type: research
Extended normobaric hyperoxia therapy yields greater neuroprotection for focal transient ischemia-reperfusion in rats
Conclusions
Under our experimental conditions, longer duration of NBO treatment produced greater benefits in focal transient cerebral ischemia-reperfusion rats. (Source: Medical Gas Research)
Source: Medical Gas Research - August 10, 2014 Category: Biomedical Science Source Type: research
Can carbon monoxide-poisoned victims be organ donors?
Abstract
The increasing demand for organ allografts to treat end-stage organ failure has driven changes in traditional donor criteria. Patients who have succumbed to carbon monoxide (CO) poisoning, a common cause of toxicological mortality, are usually rejected as organ donors. To fulfill the increasing demand, selection criteria must be expanded to include CO-poisoned donors. However, the use of allografts exposed to high CO concentrations is still under debate. Basic research and literature review data suggest that patients with brain death caused by CO poisoning should be considered appropriate organ...
Source: Medical Gas Research - July 31, 2014 Category: Biomedical Science Source Type: research
Hyperbaric oxygen therapy fails to reduce hydrocephalus formation following subarachnoid hemorrhage in rats
Conclusion
Multiple HBO therapy does not ameliorate hydrocephalus formation in a rat model of SAH; however, HBO tendentially improved the neurological functions and spatial learning and memory abilities in rats with hydrocephalus. (Source: Medical Gas Research)
Source: Medical Gas Research - July 9, 2014 Category: Biomedical Science Source Type: research
Expression analysis following argon treatment in an in vivo model of transient middle cerebral artery occlusion in rats
Conclusion
In our study, we found an elevated expression of several inflammatory markers and growth factors following tMCAO + argon compared to tMCAO + placebo. Although conflicting the previously described neuroprotective effects of argon following experimental ischemia, these findings might still be associated with each other. Further studies will have to evaluate their relevance and potential relationship. (Source: Medical Gas Research)
Source: Medical Gas Research - June 6, 2014 Category: Biomedical Science Source Type: research
