Defining the minimally effective dose and schedule for parenteral hydrogen sulfide: long-term benefits in a rat model of hindlimb ischemia
ConclusionsThese data, together with other published observations, demonstrate the efficacy of hydrogen sulfide in restoring perfusion to chronically ischemic tissue and establish a minimum efficacious dose in the rat hindlimb model. (Source: Medical Gas Research)
Source: Medical Gas Research - April 16, 2015 Category: Biomedical Science Source Type: research
Hyperbaric oxygen therapy ameliorates TNBS-induced acute distal colitis in rats
Conclusions
The results indicate that hyperbaric oxygen attenuates the severity of acute distal colitis through the down-regulation of pro-inflammatory events. (Source: Medical Gas Research)
Source: Medical Gas Research - April 16, 2015 Category: Biomedical Science Source Type: research
Defining the minimally effective dose and schedule for parenteral hydrogen sulfide: long-term benefits in a rat model of hindlimb ischemia
Conclusions
These data, together with other published observations, demonstrate the efficacy of hydrogen sulfide in restoring perfusion to chronically ischemic tissue and establish a minimum efficacious dose in the rat hindlimb model. (Source: Medical Gas Research)
Source: Medical Gas Research - April 16, 2015 Category: Biomedical Science Source Type: research
The H2S-releasing naproxen derivative, ATB-346, inhibits alveolar bone loss and inflammation in rats with ligature-induced periodontitis
ConclusionThe H2S-releasing moiety in the ATB-346 compound not only does not impair the effects of the parent naproxen on periodontitis, but also improves bone quality and prevents the gastric mucosa damage due to prostaglandin inhibition, thus configuring a potentially new adjuvant therapy for periodontal diseases. (Source: Medical Gas Research)
Source: Medical Gas Research - February 27, 2015 Category: Biomedical Science Source Type: research
The H 2 S-releasing naproxen derivative, ATB-346, inhibits alveolar bone loss and inflammation in rats with ligature-induced periodontitis
ConclusionThe H2S-releasing moiety in the ATB-346 compound not only does not impair the effects of the parent naproxen on periodontitis, but also improves bone quality and prevents the gastric mucosa damage due to prostaglandin inhibition, thus configuring a potentially new adjuvant therapy for periodontal diseases. (Source: Medical Gas Research)
Source: Medical Gas Research - February 27, 2015 Category: Biomedical Science Source Type: research
The H 2 S-releasing naproxen derivative, ATB-346, inhibits alveolar bone loss and inflammation in rats with ligature-induced periodontitis
Conclusion
The H2S-releasing moiety in the ATB-346 compound not only does not impair the effects of the parent naproxen on periodontitis, but also improves bone quality and prevents the gastric mucosa damage due to prostaglandin inhibition, thus configuring a potentially new adjuvant therapy for periodontal diseases. (Source: Medical Gas Research)
Source: Medical Gas Research - February 27, 2015 Category: Biomedical Science Source Type: research
Hyperbaric oxygen therapy in China
This article mainly reviewed the indications and contraindications of HBOT, as well as the status of clinical and experimental HBOT research in China. At the same time, there is a brief introduction of hyper baric oxygen preconditioning (HBO-PC) in China. (Source: Medical Gas Research)
Source: Medical Gas Research - February 18, 2015 Category: Biomedical Science Source Type: research
Hyperbaric oxygen therapy in China
This article mainly reviewed the indications and contraindications of HBOT, as well as the status of clinical and experimental HBOT research in China. At the same time, there is a brief introduction of hyperbaric oxygen preconditioning (HBO-PC) in China. (Source: Medical Gas Research)
Source: Medical Gas Research - February 18, 2015 Category: Biomedical Science Source Type: research
Stimulation of human damaged sperm motility with hydrogen molecule
ConclusionsOur results illustrated that H2 treatment stimulates low sperm motility. H2 is a new promising tool for male infertility treatments. (Source: Medical Gas Research)
Source: Medical Gas Research - January 10, 2015 Category: Biomedical Science Source Type: research
Exogenous hydrogen sulfide mitigates the fatty liver in obese mice through improving lipid metabolism and antioxidant potential
ConclusionH2S could mitigate the fatty liver by improving lipid metabolism and antioxidant potential in HFD-induced obese mice. (Source: Medical Gas Research)
Source: Medical Gas Research - January 10, 2015 Category: Biomedical Science Source Type: research
Stimulation of human damaged sperm motility with hydrogen molecule
Conclusions
Our results illustrated that H2 treatment stimulates low sperm motility. H2 is a new promising tool for male infertility treatments. (Source: Medical Gas Research)
Source: Medical Gas Research - January 10, 2015 Category: Biomedical Science Source Type: research
Exogenous hydrogen sulfide mitigates the fatty liver in obese mice through improving lipid metabolism and antioxidant potential
Conclusion
H2S could mitigate the fatty liver by improving lipid metabolism and antioxidant potential in HFD-induced obese mice. (Source: Medical Gas Research)
Source: Medical Gas Research - January 10, 2015 Category: Biomedical Science Source Type: research
Argon prevents the development of locomotor sensitization to amphetamine and amphetamine-induced changes in mu opioid receptor in the nucleus accumbens
AbstractSystemic administration of γ-amino-butyric acid type A (GABA-A) and benzodiazepine receptor agonists has been reported to block the development of locomotor sensitization to amphetamine. Here, we investigated whether the non-anesthetic noble gas argon, shown to possess agonistic properties at these receptors, may block the a cquisition of amphetamine-induced locomotor sensitization and mu opioid receptor activation in the nucleus accumbens. Rats were pretreated with saline solution or amphetamine (1 mg/kg) from day 1 to day 3 and then exposed, immediately after injection of amphetamine, to medicinal air or argon ...
Source: Medical Gas Research - December 29, 2014 Category: Biomedical Science Source Type: research
Argon prevents the development of locomotor sensitization to amphetamine and amphetamine-induced changes in mu opioid receptor in the nucleus accumbens
Abstract
Systemic administration of γ-amino-butyric acid type A (GABA-A) and benzodiazepine receptor agonists has been reported to block the development of locomotor sensitization to amphetamine. Here, we investigated whether the non-anesthetic noble gas argon, shown to possess agonistic properties at these receptors, may block the acquisition of amphetamine-induced locomotor sensitization and mu opioid receptor activation in the nucleus accumbens. Rats were pretreated with saline solution or amphetamine (1 mg/kg) from day 1 to day 3 and then exposed, immediately after injection of amphetamine, to med...
Source: Medical Gas Research - December 29, 2014 Category: Biomedical Science Source Type: research
Hydrogen sulfide provides cardioprotection against myocardial/ischemia reperfusion injury in the diabetic state through the activation of the RISK pathway
ConclusionThese findings provide important information that myocardial Erk1/2 activation by Na2S therapy following MI/R sets into motion events, which ultimately lead to cardioprotection in the setting of diabetes. (Source: Medical Gas Research)
Source: Medical Gas Research - December 12, 2014 Category: Biomedical Science Source Type: research
