Radiofrequency properties of two different Licox ® parenchymal brain tissue oxygen probe designs
Neuroimaging and continuous multimodality neuromonitoring are both central to the intensive care management of patients with severe traumatic brain injury [1]. Guidelines recommend the use of multimodality monitors including brain tissue oxygen (PbtO2) sensors to assess the adequacy of cerebral oxygen delivery [2]. Devices such as the Licox ® sensor (Integra LifeSciences, Plainsboro, NJ) employ a miniature implantable electrochemical cell. Temperature compensation is essential for accurate measurements and the device is now available with an integrated temperature sensor (Model CC1P1)[3]. (Source: Magnetic Resonance Imaging)
Source: Magnetic Resonance Imaging - March 16, 2018 Category: Radiology Authors: Ari Ercole Source Type: research

Asymmetric Orientation Distribution Functions (AODFs) revealing intravoxel geometry in diffusion MRI
Characterization of anisotropy via diffusion MRI reveals fiber crossings in a substantial portion of voxels within the white-matter (WM) regions of the human brain. A considerable number of such voxels could exhibit asymmetric features such as bends and junctions. However, widely employed reconstruction methods yield symmetric Orientation Distribution Functions (ODFs) even when the underlying geometry is asymmetric. In this paper, we employ inter-voxel directional filtering approaches through a cone model to reveal more information regarding the cytoarchitectural organization within the voxel. (Source: Magnetic Resonance Imaging)
Source: Magnetic Resonance Imaging - March 14, 2018 Category: Radiology Authors: Suheyla Cetin Karayumak, Evren Özarslan, Gozde Unal Source Type: research

T1, diffusion tensor, and quantitative magnetization transfer imaging of the hippocampus in an Alzheimer's disease mouse model
Alzheimer's disease (AD) pathology causes microstructural changes in the brain. These changes, if quantified with magnetic resonance imaging (MRI), could be studied for use as an early biomarker for AD. The aim of our study was to determine if T1 relaxation, diffusion tensor imaging (DTI), and quantitative magnetization transfer imaging (qMTI) metrics could reveal changes within the hippocampus and surrounding white matter structures in ex vivo transgenic mouse brains overexpressing human amyloid precursor protein with the Swedish mutation. (Source: Magnetic Resonance Imaging)
Source: Magnetic Resonance Imaging - March 12, 2018 Category: Radiology Authors: Heather T. Whittaker, Shenghua Zhu, Domenico L. Di Curzio, Richard Buist, Xin-Min Li, Suzanna Noy, Frances K. Wiseman, Jonathan D. Thiessen, Melanie Martin Tags: Original contribution Source Type: research

Estimation of perfusion properties with MR Fingerprinting Arterial Spin Labeling
In this study, the acquisition of ASL data and quantification of multiple hemodynamic parameters was explored using a Magnetic Resonance Fingerprinting (MRF) approach. A pseudo-continuous ASL labeling scheme was used with pseudo-randomized timings to acquire the MRF ASL data in a 2.5  min acquisition. A large dictionary of MRF ASL signals was generated by combining a wide range of physical and hemodynamic properties with the pseudo-random MRF ASL sequence and a two-compartment model. The acquired signals were matched to the dictionary to provide simultaneous quantification of cerebral blood flow, tissue time-to-peak, cer...
Source: Magnetic Resonance Imaging - March 12, 2018 Category: Radiology Authors: Katherine L. Wright, Yun Jiang, Dan Ma, Douglas C. Noll, Mark A. Griswold, Vikas Gulani, Luis Hernandez-Garcia Tags: Original contribution Source Type: research

Differentiating benign and malignant inflammatory breast lesions: Value of T2 weighted and diffusion weighted MR images
Benign and malignant inflammatory breast lesions demonstrate similar findings on both T2 weighted imaging (T2WI) and dynamic contrast enhanced (DCE) images. We hypothesized that benign inflammatory lesions might be differentiated form malignancies using a combination of apparent diffusion coefficient (ADC) values derived from diffusion weighted images (DWI) and T2WI. (Source: Magnetic Resonance Imaging)
Source: Magnetic Resonance Imaging - March 12, 2018 Category: Radiology Authors: Shotaro Kanao, Masako Kataoka, Mami Iima, Debra Masako Ikeda, Masakazu Toi, Kaori Togashi Tags: Original contribution Source Type: research

Hybrid quantitative MRI using chemical shift displacement and recovery-based simultaneous water and lipid imaging: A preliminary study
To suppress olefinic signals and enable simultaneous and quantitative estimation of multiple functional parameters associated with water and lipid, we investigated a modified method using chemical shift displacement and recovery-based separation of lipid tissue (SPLIT) involving acquisitions with different inversion times (TIs), echo times (TEs), and b-values. (Source: Magnetic Resonance Imaging)
Source: Magnetic Resonance Imaging - March 12, 2018 Category: Radiology Authors: Naoki Ohno, Tosiaki Miyati, Shuto Suzuki, Hirohito Kan, Toshitaka Aoki, Yoshitaka Nakamura, Yuki Hiramatsu, Satoshi Kobayashi, Toshifumi Gabata Tags: Technical note Source Type: research

T1, diffusion tensor, and quantitative magnetization transfer imaging of the hippocampus in an Alzheimer's disease mouse model
Alzheimer's disease (AD) pathology causes microstructural changes in the brain. These changes, if quantified with magnetic resonance imaging (MRI), could be studied for use as an early biomarker for AD. The aim of our study was to determine if T1 relaxation, diffusion tensor imaging (DTI), and quantitative magnetization transfer imaging (qMTI) metrics could reveal changes within the hippocampus and surrounding white matter structures in ex vivo transgenic mouse brains overexpressing human amyloid precursor protein with the Swedish mutation. (Source: Magnetic Resonance Imaging)
Source: Magnetic Resonance Imaging - March 12, 2018 Category: Radiology Authors: Heather T. Whittaker, Shenghua Zhu, Domenico L. Di Curzio, Richard Buist, Xin-Min Li, Suzanna Noy, Frances K. Wiseman, Jonathan D. Thiessen, Melanie Martin Tags: Original contribution Source Type: research

Estimation of perfusion properties with MR fingerprinting arterial spin labeling
In this study, the acquisition of ASL data and quantification of multiple hemodynamic parameters was explored using a Magnetic Resonance Fingerprinting (MRF) approach. A pseudo-continuous ASL labeling scheme was used with pseudo-randomized timings to acquire the MRF ASL data in a 2.5  min acquisition. A large dictionary of MRF ASL signals was generated by combining a wide range of physical and hemodynamic properties with the pseudo-random MRF ASL sequence and a two-compartment model. The acquired signals were matched to the dictionary to provide simultaneous quantification of cerebral blood flow, tissue time-to-peak, cer...
Source: Magnetic Resonance Imaging - March 12, 2018 Category: Radiology Authors: Katherine L. Wright, Yun Jiang, Dan Ma, Douglas C. Noll, Mark A. Griswold, Vikas Gulani, Luis Hernandez-Garcia Tags: Original contribution Source Type: research

Differentiating benign and malignant inflammatory breast lesions: Value of T2 weighted and diffusion weighted MR images
Benign and malignant inflammatory breast lesions demonstrate similar findings on both T2 weighted imaging (T2WI) and dynamic contrast enhanced (DCE) images. We hypothesized that benign inflammatory lesions might be differentiated form malignancies using a combination of apparent diffusion coefficient (ADC) values derived from diffusion weighted images (DWI) and T2WI. (Source: Magnetic Resonance Imaging)
Source: Magnetic Resonance Imaging - March 12, 2018 Category: Radiology Authors: Shotaro Kanao, Masako Kataoka, Mami Iima, Debra Masako Ikeda, Masakazu Toi, Kaori Togashi Tags: Original contribution Source Type: research

Hybrid quantitative MRI using chemical shift displacement and recovery-based simultaneous water and lipid imaging: A preliminary study
To suppress olefinic signals and enable simultaneous and quantitative estimation of multiple functional parameters associated with water and lipid, we investigated a modified method using chemical shift displacement and recovery-based separation of lipid tissue (SPLIT) involving acquisitions with different inversion times (TIs), echo times (TEs), and b-values. (Source: Magnetic Resonance Imaging)
Source: Magnetic Resonance Imaging - March 12, 2018 Category: Radiology Authors: Naoki Ohno, Tosiaki Miyati, Shuto Suzuki, Hirohito Kan, Toshitaka Aoki, Yoshitaka Nakamura, Yuki Hiramatsu, Satoshi Kobayashi, Toshifumi Gabata Tags: Technical note Source Type: research

Delayed reaction following gadolinium-based contrast agent application
Both iodinated contrast media and gadolinium-based contrast agents (GBCAs) can induce immediate hypersensitivity reactions. In addition, iodinated contrast media have been shown to be responsible for delayed or non-immediate reactions that occur 1  h up to several days following iodinated contrast medium-injection.Here we for the first time present a female patient who acquired a delayed reaction after the application of a gadolinium-based contrast agent. (Source: Magnetic Resonance Imaging)
Source: Magnetic Resonance Imaging - March 11, 2018 Category: Radiology Authors: Ingrid Boehm, Johannes T. Heverhagen Source Type: research

Noninvasive imaging of cerebral blood volume in piglets with vascular occupancy MR imaging and inflow vascular space occupancy with dynamic subtraction
Accurate quantitative non-invasive assessments of arterial cerebral blood volume (aCBV) can greatly benefit the study of cerebral vascular health in both humans and in animal models. In recent years, progress has been made in the techniques available to quantify CBV with magnetic resonance imaging (MRI). Here, we compared a non-invasive technique, measuring inflowing vascular space occupancy with dynamic subtraction (iVASO-ds) with a contrast-based vascular space occupancy measurement in piglets. (Source: Magnetic Resonance Imaging)
Source: Magnetic Resonance Imaging - March 11, 2018 Category: Radiology Authors: Benjamin J. Zimmerman, Austin T. Mudd, Joanne E. Fil, Ryan N. Dilger, Bradley P. Sutton Tags: Original contribution Source Type: research

Pulseq-Graphical Programming Interface: Open source visual environment for prototyping pulse sequences and integrated magnetic resonance imaging algorithm development
To provide a single open-source platform for comprehensive MR algorithm development inclusive of simulations, pulse sequence design and deployment, reconstruction, and image analysis. (Source: Magnetic Resonance Imaging)
Source: Magnetic Resonance Imaging - March 11, 2018 Category: Radiology Authors: R. Keerthi Sravan, Sneha Potdar, Pavan Poojar, Ashok Kumar Reddy, Stefan Kroboth, Jon-Fredrik Nielsen, Maxim Zaitsev, Ramesh Venkatesan, Sairam Geethanath Tags: Technical note Source Type: research

Delayed reaction following gadolinium-based contrast agent application
Both iodinated contrast media and gadolinium-based contrast agents (GBCAs) can induce immediate hypersensitivity reactions. In addition, iodinated contrast media have been shown to be responsible for delayed or non-immediate reactions that occur 1  h up to several days following iodinated contrast medium-injection.Here we for the first time present a female patient who acquired a delayed reaction after the application of a gadolinium-based contrast agent. (Source: Magnetic Resonance Imaging)
Source: Magnetic Resonance Imaging - March 11, 2018 Category: Radiology Authors: Ingrid Boehm, Johannes T. Heverhagen Source Type: research