Estimation of perfusion properties with MR fingerprinting arterial spin labeling

In this study, the acquisition of ASL data and quantification of multiple hemodynamic parameters was explored using a Magnetic Resonance Fingerprinting (MRF) approach. A pseudo-continuous ASL labeling scheme was used with pseudo-randomized timings to acquire the MRF ASL data in a 2.5  min acquisition. A large dictionary of MRF ASL signals was generated by combining a wide range of physical and hemodynamic properties with the pseudo-random MRF ASL sequence and a two-compartment model. The acquired signals were matched to the dictionary to provide simultaneous quantification of cerebral blood flow, tissue time-to-peak, cerebral blood volume, arterial time-to-peak, B1, and T1.

Source: Magnetic Resonance Imaging - March 12, 2018 Category: Radiology Authors: Katherine L. Wright, Yun Jiang, Dan Ma, Douglas C. Noll, Mark A. Griswold, Vikas Gulani, Luis Hernandez-Garcia Tags: Original contribution Source Type: research