28Si total body irradiation injures bone marrow hematopoietic stem cells via induction of cellular apoptosis
Publication date: Available online 5 April 2017 Source:Life Sciences in Space Research Author(s): Jianhui Chang, Wei Feng, Yingying Wang, Antiño R. Allen, Jennifer Turner, Blair Stewart, Jacob Raber, Martin Hauer-Jensen, Daohong Zhou, Lijian Shao Long-term space mission exposes astronauts to a radiation environment with potential health hazards. High-energy charged particles (HZE), including 28Si nuclei in space, have deleterious effects on cells due to their characteristics with high linear energy transfer and dense ionization. The influence of 28Si ions contributes more than 10% to the radiation dose equival...
Source: Life Sciences in Space Research - April 5, 2017 Category: Biology Source Type: research
BION-M 1: First continuous blood pressure monitoring in mice during a 30-day spaceflight
Publication date: May 2017 Source:Life Sciences in Space Research, Volume 13 Author(s): Alexander Andreev-Andrievskiy, Anfisa Popova, Jean-Christophe Lloret, Patrick Aubry, Anatoliy Borovik, Daria Tsvirkun, Olga Vinogradova, Eugeniy Ilyin, Guillemette Gauquelin-Koch, Claude Gharib, Marc-Antoine Custaud Animals are an essential component of space exploration and have been used to demonstrate that weightlessness does not disrupt essential physiological functions. They can also contribute to space research as models of weightlessness-induced changes in humans. Animal research was an integral component of the 30-d...
Source: Life Sciences in Space Research - April 5, 2017 Category: Biology Source Type: research
Track structure model of microscopic energy deposition by protons and heavy ions in segments of neuronal cell dendrites represented by cylinders or spheres
Publication date: Available online 2 April 2017 Source:Life Sciences in Space Research Author(s): Murat Alp, Francis A. Cucinotta Changes to cognition, including memory, following radiation exposure are a concern for cosmic ray exposures to astronauts and in Hadron therapy with proton and heavy ion beams. The purpose of the present work is to develop computational methods to evaluate microscopic energy deposition (ED) in volumes representative of neuron cell structures, including segments of dendrites and spines, using a stochastic track structure model. A challenge for biophysical models of neuronal damage is the larg...
Source: Life Sciences in Space Research - April 2, 2017 Category: Biology Source Type: research
The radiation environment on the surface of Mars – Numerical calculations of the galactic component with GEANT4/PLANETOCOSMICS
Publication date: Available online 1 April 2017 Source:Life Sciences in Space Research Author(s): Daniel Matthiä, Thomas Berger Galactic cosmic radiation and secondary particles produced in the interaction with the atmosphere lead to a complex radiation field on the Martian surface. A workshop (“1st Mars Space Radiation Modeling Workshop”) organized by the MSL-RAD science team was held in June 2016 in Boulder with the goal to compare models capable to predict this radiation field with each other and measurements from the RAD instrument onboard the curiosity rover taken between 15 November 2015 and 15 January 2016....
Source: Life Sciences in Space Research - April 1, 2017 Category: Biology Source Type: research
BION-M1: First Continuous Blood Pressure Monitoring in Mice during a 30-day Spaceflight
Publication date: Available online 28 March 2017 Source:Life Sciences in Space Research Author(s): Alexander Andreev-Andrievskiy, Anfisa Popova, Jean-Christophe Lloret, Patrick Aubry, Anatoliy Borovik, Daria Tsvirkun, Olga Vinogradova, Eugeniy Ilyin, Guillemette Gauquelin-Koch, Claude Gharib, Marc-Antoine Custaud Animals are an essential component of space exploration and have been used to demonstrate that weightlessness does not disrupt essential physiological functions. They can also contribute to space research as models of weightlessness-induced changes in humans. Animal research was an integral component ...
Source: Life Sciences in Space Research - March 28, 2017 Category: Biology Source Type: research
