Journal of Tissue Engineering and Regenerative Medicine This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Issue Information
No abstract is available for this article. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - March 12, 2018 Category: Biotechnology Tags: ISSUE INFORMATION Source Type: research

Cover Image, Volume 12, Issue 3
The cover image, by James E. Dennis et al., is based on the Research Article Tissue engineering of a composite trachea construct using autologous rabbit chondrocytes, DOI: 10.1002/term.2523. Illustration Credit: Kathleen Wagner and Jordan Peitz. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - March 12, 2018 Category: Biotechnology Authors: James E. Dennis, Kristina G. Bernardi, Thomas J. Kean, Nelson E. Liou, Tanya K. Meyer Tags: COVER IMAGE Source Type: research

An endochondral ossification approach to early stage bone repair: Use of tissue ‐engineered hypertrophic cartilage constructs as primordial templates for weight‐bearing bone repair
Journal of Tissue Engineering and Regenerative Medicine, EarlyView. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - March 8, 2018 Category: Biotechnology Source Type: research

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Journal of Tissue Engineering and Regenerative Medicine, Ahead of Print. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - March 8, 2018 Category: Biotechnology Source Type: research

An endochondral ossification approach to early stage bone repair: Use of tissue ‐engineered hypertrophic cartilage constructs as primordial templates for weight‐bearing bone repair
This study demonstrates the value of combining knowledge of development biology and tissue engineering in a developmental engineering inspired approach to tissue repair. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - March 8, 2018 Category: Biotechnology Authors: Amos Matsiko, Emmet M. Thompson, Cai Lloyd ‐Griffith, Gráinne M. Cunniffe, Tatiana Vinardell, John P. Gleeson, Daniel J. Kelly, Fergal J. O'Brien Tags: SHORT COMMUNICATION Source Type: research

In Vitro 3D Regeneration ‐like Growth of Human Patient Brain Tissue
Abstract In vitro culture of primary neurons are widely adapted with embryonic but not mature brain tissue. Here, we extended a previously developed bioengineered 3D embryonic brain tissue model to resected normal patient brain tissue in an attempt to regenerate human neurons in vitro. Single cells and small sized (diameter < 100 μm) spheroids from dissociated brain tissue were seeded into 3D silk fibroin‐based scaffolds, with or without collagen or Matrigel, and compared with 2D cultures and scaffold‐free suspension cultures. Changes of cell phenotypes (neuronal, astroglial, neural progenitor and neuroepithelial) ...
Source: Journal of Tissue Engineering and Regenerative Medicine - March 6, 2018 Category: Biotechnology Authors: M.D. Tang ‐Schomer, W.B. Wu, D.L. Kaplan, M.J. Bookland Tags: RESEARCH ARTICLE Source Type: research

Therapeutic effects of a recombinant human collagen peptide bioscaffold with human adipose ‐derived stem cells on impaired wound healing after radiotherapy
Journal of Tissue Engineering and Regenerative Medicine, EarlyView. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - March 4, 2018 Category: Biotechnology Source Type: research

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Journal of Tissue Engineering and Regenerative Medicine, Ahead of Print. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - March 4, 2018 Category: Biotechnology Source Type: research

Decellularized pancreas as a native extracellular matrix scaffold for pancreatic islet seeding and culture
In this study, mouse pancreata were decellularized by perfusion using 0.5% sodium dodecyl sulphate (SDS). Different characterizations revealed that the resulting matrix was free of cells and retained part of the pancreas ECM including the vasculature and its internal elastic basal lamina, the ducts with their basal membrane as well as the glycosaminoglycan and collagen structures. Islets were infused into the ductal system of decellularized pancreata and glucose‐stimulated insulin secretion (GSIS) results confirmed their functionality after 48h. Also, re‐cellularizing the decellularized pancreas with GFP‐tagged INS�...
Source: Journal of Tissue Engineering and Regenerative Medicine - March 2, 2018 Category: Biotechnology Authors: Rajesh Guruswamy Damodaran, Patrick Vermette Tags: RESEARCH ARTICLE Source Type: research

Differentiation of Human Induced Pluripotent Stem Cell under Flow Conditions to Mature Hepatocytes for Liver Tissue Engineering
In conclusion, the hiPSC differentiated under flow conditions towards hepatocytes express a wide spectrum of liver functions at levels comparable to hPCLS indicating excellent future perspectives for the development of a bioartificial liver system for toxicity testing or as liver support device for patients. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - March 2, 2018 Category: Biotechnology Authors: Viktoriia Starokozhko, Mette Hemmingsen, Layla Larsen, Soumyaranjan Mohanty, Marjolijn Merema, C. Rodrigo Pimentel, Anders Wolff, Jenny Emn éus, Anders Aspegren, Geny Groothuis, Martin Dufva Tags: RESEARCH ARTICLE Source Type: research

Novel Cellulose/Hydroxyapatite Scaffolds for Bone Tissue Regeneration: in vitro and in vivo study
Abstract Cellulose scaffolds containing nano‐ or micro‐hydroxyapatite (nHA or μHA) were prepared by the regeneration of cellulose from its acetylated derivative and the mechanical immobilization of inorganic particles, followed by freeze‐drying. Microtomographic (μCT) evaluation revealed that both scaffolds presented a highly interconnected porous structure, with a mean pore diameter of 490±94 μm and 540±132 μm for cellulose/nHA and cellulose/μHA, respectively. In vitro and in vivo characterizations of the developed scaffolds were investigated. Commercially available bone allograft was used as a control materi...
Source: Journal of Tissue Engineering and Regenerative Medicine - March 2, 2018 Category: Biotechnology Authors: Povilas Daugela, Mindaugas Pranskunas, Gintaras Juodzbalys, Jolanta Liesiene, Odeta Baniukaitiene, Am érico Afonso, Pedro Sousa Gomes Tags: RESEARCH ARTICLE Source Type: research

Novel injectable gellan gum hydrogel composites incorporating Zn ‐ and Sr‐enriched bioactive glass microparticles: high‐resolution X‐Ray micro‐computed tomography, antibacterial and in vitro testing
In this study, gellan gum (GG) hydrogels were formed by simple mixing of GG solution with bioactive glass microparticles of 45S5 composition, leading to hydrogel formation by ion release from the amorphous bioactive glass microparticles. This resulted in novel injectable, self‐gelling composites of GG hydrogels containing 20% bioactive glass. Gelation occurred within 20 minutes. Composites containing the standard 45S5 bioactive glass preparation were markedly less stiff. X‐ray μCT proved to be a highly sensitive technique capable of detecting microparticles of diameter approximately 8 μm, i.e. individual microparticl...
Source: Journal of Tissue Engineering and Regenerative Medicine - February 28, 2018 Category: Biotechnology Authors: Timothy E.L. Douglas, Michal Dziadek, Svetlana Gorodzha, Jana Li šková, Gilles Brackman, Valérie Vanhoorne, Chris Vervaet, Lieve Balcaen, Maria Rosario Florez Garcia, Aldo R. Boccaccini, Venera Weinhardt, Tilo Baumbach, Frank Vanhaecke, Tom Coenye, Luc Tags: RESEARCH ARTICLE Source Type: research

Biomimetic scaffolds and dynamic compression enhance the properties of chondrocyte ‐ and MSC‐based tissue‐engineered cartilage
In conclusion, the microenvironment provided by SF‐GCH scaffolds and dynamic compression enhances chondrocyte biosynthesis and matrix accumulation, indicating their potential for cartilage tissue engineering applications. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - February 28, 2018 Category: Biotechnology Authors: Nopporn Sawatjui, Temduang Limpaiboon, Karsten Schrobback, Travis Klein Tags: RESEARCH ARTICLE Source Type: research

Assessing glucose and oxygen diffusion in hydrogels for the rational design of 3D stem cell scaffolds in regenerative medicine
Abstract Hydrogels are attractive biomaterials for replicating cellular microenvironments, but attention needs to be given to hydrogels diffusion properties. A large body of literature shows the promise of hydrogels as 3D culture models, cell expansion systems, cell delivery vehicles and tissue constructs. Surprisingly, literature seems to have overlooked the important effects of nutrient diffusion on the viability of hydrogel‐encapsulated cells. In this paper, we present the methods and results of an investigation into glucose and oxygen diffusion into a silated‐hydroxypropylmethylcellulose (Si‐HPMC) hydrogel. Using...
Source: Journal of Tissue Engineering and Regenerative Medicine - February 28, 2018 Category: Biotechnology Authors: L. Figueiredo, R. Pace, C. d ’Arros, G. Réthoré, J. Guicheux, C. Le Visage, P. Weiss Tags: RESEARCH ARTICLE Source Type: research