Differentiation of Human Induced Pluripotent Stem Cell under Flow Conditions to Mature Hepatocytes for Liver Tissue Engineering

In conclusion, the hiPSC differentiated under flow conditions towards hepatocytes express a wide spectrum of liver functions at levels comparable to hPCLS indicating excellent future perspectives for the development of a bioartificial liver system for toxicity testing or as liver support device for patients.

Source: Journal of Tissue Engineering and Regenerative Medicine - March 2, 2018 Category: Biotechnology Authors: Viktoriia Starokozhko, Mette Hemmingsen, Layla Larsen, Soumyaranjan Mohanty, Marjolijn Merema, C. Rodrigo Pimentel, Anders Wolff, Jenny Emn éus, Anders Aspegren, Geny Groothuis, Martin Dufva Tags: RESEARCH ARTICLE Source Type: research