Journal of the American Society of Cytopathology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Milan Interobserver Reproducibility Study (MIRST): Milan System 2018
ConclusionsSimilar to the reproducibility studies conducted for gynecologic and urinary cytopathology, the most important factor in diagnostic reproducibility was a priori classification of image difficulty although people with higher certifications performed better. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - February 11, 2020 Category: Cytology Source Type: research

Endocervical Glandular Involvement is Associated with an Increased Detection Rate of High-Grade Squamous Intraepithelial Lesions on the Pap Test
ConclusionOverall, the diagnosis of HSIL-EGI on Pap test specimens is complicated by poor sensitivity and interobserver concordance. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - February 10, 2020 Category: Cytology Source Type: research

Infectious Disease Diagnosed by Fine Needle Aspirate Biopsy
ConclusionsOur study has shown that FNAB with high sensitivity in detecting infection and that negative cytology correlates with a negative infectious work up. Although infection in the setting of neoplasia is uncommon, it should be considered if there is clinical data to suggest infection. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - February 9, 2020 Category: Cytology Source Type: research

Utility of Claudin-4 versus BerEP4 and B72.3 in Pleural Fluids with Metastatic Lung Adenocarcinoma
ConclusionsIn this study, Claudin-4 performed superiorly compared to BerEP4 and B72.3 in distinguishing lung adenocarcinoma from RMC/MM in pleural effusions. Our results show claudin-4 is a useful marker for distinguishing RMC and MM from lung adenocarcinoma, with high sensitivity (100%) and specificity (100%), compatible with studies shown in the literature. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - February 7, 2020 Category: Cytology Source Type: research

Cytodiagnosis and Protein Typing of Amyloid from a Vitreous Washing: Initial Diagnostic Workup of Hereditary Amyloidosis
We describe a 64-year-old man with a history of heart disease and peripheral neuropathy who presented with asymmetric visual disturbances and vitreous opacities, leading to diagnostic vitrectomy. Amyloid was identified on a ThinPrep slide of the vitreous sample via Congo red stain. Creation of a cell block from the residual ThinPrep sample allowed for amyloid protein typing, identifying ATTR (transthyretin) –type amyloid and strongly suggesting hereditary amyloidosis. Subsequent sequencing of the patient’s TTR gene identified a pathogenic variant that is associated with autosomal dominant hereditary transthyretin-media...
Source: Journal of the American Society of Cytopathology - February 7, 2020 Category: Cytology Source Type: research