Utility of Claudin-4 versus BerEP4 and B72.3 in Pleural Fluids with Metastatic Lung Adenocarcinoma

ConclusionsIn this study, Claudin-4 performed superiorly compared to BerEP4 and B72.3 in distinguishing lung adenocarcinoma from RMC/MM in pleural effusions. Our results show claudin-4 is a useful marker for distinguishing RMC and MM from lung adenocarcinoma, with high sensitivity (100%) and specificity (100%), compatible with studies shown in the literature.
Source: Journal of the American Society of Cytopathology - Category: Cytology Source Type: research