Summary article on Advanced Ulcer Treatments used in the Operating Room
Debridement is important throughout the process. There ’s a lot of discussion in the medical literature about the factors that contribute to chronic wounds or nonhealing wounds, high inflammatory cytokine burden, high bacterial content in the wounds, senescent wound cells, high MMPs (Source: Journal of the American College of Certified Wound Specialists)
Source: Journal of the American College of Certified Wound Specialists - January 17, 2018 Category: Dermatology Authors: Christopher L. Winters Source Type: research

Impact of Renal Failure on Wounds Healing
Population of patients with the impaired kidney function grows around the world. With the advances of the contemporary medicine people live to the older age, survive cardiac and cerebrovascular events, recover from the complex surgeries, overcome malignancies, infections and autoimmune diseases. That all frequently leads to the development of variable degree of chronic kidney impairment in form of interstitial and/or glomerular injury. Patients with chronic kidney disease (CKD) often share risk factors of hypertension, poorly controlled diabetes mellitus, arterial and venous vascular disease, obesity, malnutrition and chro...
Source: Journal of the American College of Certified Wound Specialists - January 17, 2018 Category: Dermatology Authors: Natallia Maroz Source Type: research

Editorial: Hyperbaric Oxygen Therapy Side Effects – Where Do We Stand?
I recently had the opportunity to present this topic at the ACCWS 7th Annual Symposium. The following is a synopsis of that presentation. We use hyperbaric oxygen therapy (HBOT) for a variety of both elective and emergent indications. It is always important to weight risk and benefit when considering patients for therapies such as HBOT. In addition to an understanding of the benefits, we must also be able to discuss the potential side effects with our patients. (Source: Journal of the American College of Certified Wound Specialists)
Source: Journal of the American College of Certified Wound Specialists - January 17, 2018 Category: Dermatology Authors: Marvin Heyboer Source Type: research

Quantitative Monitoring Wound Healing Status Through Three-dimensional Imaging on Mobile Platforms
We present a mobile platform based wound 3D imaging app. (Source: Journal of the American College of Certified Wound Specialists)
Source: Journal of the American College of Certified Wound Specialists - December 13, 2017 Category: Dermatology Authors: Adam Yee, John Harmon, Steven Yi Tags: Research Paper Source Type: research

The Death of the Kennedy Terminal Ulcer
The concept of the Kennedy Terminal Ulcer (KTU) has been ubiquitous in attempting to explain the development of pressure based tissue injuries in patients with actual or presumed terminal conditions. The concept is problematic in that it uses factors other than pressure to explain the development and progression of pressure based tissue injuries, specifically the presence of a terminal condition. Based on the most current understanding of how pressure based tissue injuries develop and progress, the concept of The Kennedy Terminal Ulcer appears to be without physiologic basis and based solely on observation. (Source: Journa...
Source: Journal of the American College of Certified Wound Specialists - December 13, 2017 Category: Dermatology Authors: Michael S. Miller Tags: Review Article Source Type: research

Quantitative monitoring wound healing status through three-dimensional imaging on mobile platforms
We present a mobile platform based wound 3D imaging app. (Source: Journal of the American College of Certified Wound Specialists)
Source: Journal of the American College of Certified Wound Specialists - December 13, 2017 Category: Dermatology Authors: Adam Yee, John Harmon, Steven Yi Source Type: research

The Death of The Kennedy Terminal Ulcer
The concept of the Kennedy Terminal Ulcer (KTU) has been ubiquitous in attempting to explain the development of pressure based tissue injuries in patients with actual or presumed terminal conditions. The concept is problematic in that it uses factors other than pressure to explain the development and progression of pressure based tissue injuries, specifically the presence of a terminal condition. Based on the most current understanding of how pressure based tissue injuries develop and progress, the concept of The Kennedy Terminal Ulcer appears to be without physiologic basis and based solely on observation. (Source: Journa...
Source: Journal of the American College of Certified Wound Specialists - December 13, 2017 Category: Dermatology Authors: Michael S. Miller Source Type: research

Placental Membranes for Management of Refractory Cutaneous Sinus Tracts of Surgical Origin: A Pilot Study
Despite advances in surgical technique, postoperative complications may lead to refractory cutaneous sinus tracts or tunnels. Negative pressure wound therapy is difficult to apply in longer tracts with a narrow diameter opening and conservative treatment failures ultimately necessitate surgical revisions. The aim of this pilot study was a clinical utility assessment of two different commercial placental membrane products for refractory cutaneous sinus tracts of surgical origin. Patients were treated with viable cryopreserved placental membrane (vCPM, n  = 6) or devitalized dehydrated amnion/chorion membrane (dHACM, n =Â...
Source: Journal of the American College of Certified Wound Specialists - September 26, 2017 Category: Dermatology Authors: Eric L. Johnson, Georgina M. Michael, Yeabsera G. Tamire Source Type: research

Placental Membranes for Management of Refractory Cutaneous Sinus Tracts of Surgical Origin: A Pilot Study
Despite advances in surgical technique, postoperative complications may lead to refractory cutaneous sinus tracts or tunnels. Negative pressure wound therapy is difficult to apply in longer tracts with a narrow diameter opening and conservative treatment failures ultimately necessitate surgical revisions. The aim of this pilot study was a clinical utility assessment of two different commercial placental membrane products for refractory cutaneous sinus tracts of surgical origin. Patients were treated with viable cryopreserved placental membrane (vCPM, n=6) or devitalized dehydrated amnion/chorion membrane (dHACM, n=6). (Sou...
Source: Journal of the American College of Certified Wound Specialists - September 26, 2017 Category: Dermatology Authors: Eric L. Johnson, Georgina M. Michael, Yeabsera G. Tamire Source Type: research

Management of a Recurrent Pyogenic Granuloma of the Inferior Lip with Pulsed Dye Laser: A Case Report
This article presents the unique and successful pulsed dye laser treatment of a labial PG on a 60-year-old patient. (Source: Journal of the American College of Certified Wound Specialists)
Source: Journal of the American College of Certified Wound Specialists - September 4, 2017 Category: Dermatology Authors: Serkan Demirkan Source Type: research

Limb-Threatening Arterial Thrombosis in a Patient with Eosinophilic Granulomatosis with Polyangiitis
We report a case of a 72 year-old male with a two-year lung-biopsy proven history of EGPA who presented with retiform purpura and patchy necrosis on his bilateral shins, which progressed to sharply demarcated, stellate ulcerations with surrounding erythema within two weeks. Laboratory work up revealed elevated anti-Cardiolipin IgM, rheumatoid factor, erythrocyte sedimentation rate, and C-reactive protein, although P-neutrophil cytoplasmic antibody (P-ANCA) and C-neutrophil cytoplasmic antibody (C-ANCA) were negative. (Source: Journal of the American College of Certified Wound Specialists)
Source: Journal of the American College of Certified Wound Specialists - March 27, 2017 Category: Dermatology Authors: Taylor Braunberger, Jessica S. Mounessa, Ryan O'Leary, Ekama Carlson, Sabrina Newman Source Type: research

Limb-threatening arterial thrombosis in a patient with eosinophilic granulomatosis with polyangiitis
We report a case of a 72 year-old male with a two-year lung-biopsy proven history of EGPA who presented with retiform purpura and patchy necrosis on his bilateral shins, which progressed to sharply demarcated, stellate ulcerations with surrounding erythema within two weeks. Laboratory work up revealed elevated anti-Cardiolipin IgM, rheumatoid factor, erythrocyte sedimentation rate, and C-reactive protein, although P-neutrophil cytoplasmic antibody (P-ANCA) and C-neutrophil cytoplasmic antibody (C-ANCA) were negative. (Source: Journal of the American College of Certified Wound Specialists)
Source: Journal of the American College of Certified Wound Specialists - March 27, 2017 Category: Dermatology Authors: Taylor Braunberger, Jessica S. Mounessa, Ryan O ’Leary, Ekama Carlson, Sabrina Newman Source Type: research

Plasma Oxidative Stress in Patients With Chronic Vascular Cutaneous Ulcers
Oxidative stress is hypothesized to be one of the main causes of the pathophysiologic alterations observed during impaired healing of wounds. In the present study, we aimed to measure systemic levels of free radicals in blood and anti-oxidant (AO) activity in the plasma of patients with chronic ulcers (venous stasis ulcers and arterial insufficiency ulcers) of lower extremities (CULEs). Oxidants and AO activity were measured in eighty-five consecutive patients with CVSUs of the lower extremities as they arrived randomly for routine visits to our ambulatory clinic. (Source: Journal of the American College of Certified Wound Specialists)
Source: Journal of the American College of Certified Wound Specialists - February 28, 2017 Category: Dermatology Authors: Edoardo Raposio, Francesco Simonacci, Davide Gorni, Michele P. Grieco Tags: Research Paper Source Type: research

Plasma Oxidative stress in patients with chronic vascular Cutaneous Ulcers
Oxidative stress is hypothesized to be one of the main causes of the pathophysiologic alterations observed during impaired healing of wounds. In the present study, we aimed to measure systemic levels of free radicals in blood and anti-oxidant (AO) activity in the plasma of patients with chronic ulcers (venous stasis ulcers and arterial insufficiency ulcers) of lower extremities (CULEs). (Source: Journal of the American College of Certified Wound Specialists)
Source: Journal of the American College of Certified Wound Specialists - February 27, 2017 Category: Dermatology Authors: Edoardo Raposio, Francesco Simonacci, Davide Gorni, Michele P. Grieco Source Type: research