Plasma Oxidative Stress in Patients With Chronic Vascular Cutaneous Ulcers

Oxidative stress is hypothesized to be one of the main causes of the pathophysiologic alterations observed during impaired healing of wounds. In the present study, we aimed to measure systemic levels of free radicals in blood and anti-oxidant (AO) activity in the plasma of patients with chronic ulcers (venous stasis ulcers and arterial insufficiency ulcers) of lower extremities (CULEs). Oxidants and AO activity were measured in eighty-five consecutive patients with CVSUs of the lower extremities as they arrived randomly for routine visits to our ambulatory clinic.

Source: Journal of the American College of Certified Wound Specialists - February 28, 2017 Category: Dermatology Authors: Edoardo Raposio, Francesco Simonacci, Davide Gorni, Michele P. Grieco Tags: Research Paper Source Type: research