Limb-threatening arterial thrombosis in a patient with eosinophilic granulomatosis with polyangiitis

We report a case of a 72 year-old male with a two-year lung-biopsy proven history of EGPA who presented with retiform purpura and patchy necrosis on his bilateral shins, which progressed to sharply demarcated, stellate ulcerations with surrounding erythema within two weeks. Laboratory work up revealed elevated anti-Cardiolipin IgM, rheumatoid factor, erythrocyte sedimentation rate, and C-reactive protein, although P-neutrophil cytoplasmic antibody (P-ANCA) and C-neutrophil cytoplasmic antibody (C-ANCA) were negative.

Source: Journal of the American College of Certified Wound Specialists - March 27, 2017 Category: Dermatology Authors: Taylor Braunberger, Jessica S. Mounessa, Ryan O ’Leary, Ekama Carlson, Sabrina Newman Source Type: research