CuSO4/sodium ascorbate catalysed synthesis of benzosuberone and 1,2,3-triazole conjugates: Design, synthesis and in vitro anti-proliferative activity
Publication date: Available online 11 May 2019Source: Journal of Saudi Chemical SocietyAuthor(s): CH.B. Praveena Devi, K. Vijay, B. Hari Babu, Syed Farooq Adil, M. Mujahid Alam, M. Vijjulatha, Mohd. Bismillah AnsariAbstractA novel series of conjugates of benzosuberone and 1,2,3-triazole i.e. 3-(4-phenyl-1H-1,2,3-triazol-1-yl)propyl-9-chloro-2,3-dimethyl-6,7-dihydro-5H-benzo[7]annulene-8-carboxylic acids (8a-j) were synthesized in good to excellent yields catalysed by CuSO4 under milder reaction conditions and evaluated for their anti-proliferative activity. The structural elucidation of the prepared compounds was carried o...
Source: Journal of Saudi Chemical Society - May 29, 2019 Category: Chemistry Source Type: research
Starch nanoparticles as a bio-nanocatalyst in synthesis of diheteroaryl thioethers
Publication date: Available online 16 May 2019Source: Journal of Saudi Chemical SocietyAuthor(s): Homeyra Rostami Monjezi, Zohre Zarnegar, Javad SafariAbstractNanostarch is shown to be a highly efficient, eco-friendly and heterogenouse organocatalyst for the synthesis of the diheteroaryl thioethers via one-pot reaction of methylcarbonyls, thiourea and iodine in DMSO. This method offers significant advantages such as available starting materials, higher purity and excellent yield of products, very easy reaction conditions and absence of any tedious purification. Furthermore, because of employing eco-friendly catalyst withou...
Source: Journal of Saudi Chemical Society - May 16, 2019 Category: Chemistry Source Type: research
Iron-Catalyzed Synthesis of Phenanthrenes via Intramolecular Hydroarylation of Arene-Alkynes
Publication date: Available online 16 May 2019Source: Journal of Saudi Chemical SocietyAuthor(s): Yang Li, Yawei Li, Xiao Hu, Guangxing Pan, Wangsheng Liu, Yaopeng Zhang, Hao GuoAbstractAn Fe(OTf)3-catalyzed intramolecular hydroarylation of arene-alkynes with high functional-group tolerance has been reported, affording a series of phenanthrene derivatives efficiently. A low catalytic amount of Fe(OTf)3 is applied in this reaction. This transformation provides a convenient and practical method for the preparation of phenanthrenes.Graphical abstract (Source: Journal of Saudi Chemical Society)
Source: Journal of Saudi Chemical Society - May 16, 2019 Category: Chemistry Source Type: research
Synthesis and in vitro anti-proliferative capabilities of steroidal thiazole and indole derivatives
Publication date: Available online 16 May 2019Source: Journal of Saudi Chemical SocietyAuthor(s): Fariha Shamim, Kanwal, Firdos Alam Khan, Muhammad Taha, Khalid Mohammed Khan, ArshiaAbstractThe synthetic derivatives (1-15) of steroidal and indole class were synthesized by using different strategies. These compounds were characterized by 1H-NMR spectroscopy and EI-MS spectrometry, respectively. The synthetic derivatives were examined for their cytotoxic effects on human adenocarcinoma cells (HCT-116) by using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay and morphometric analysis. The cytotoxic ef...
Source: Journal of Saudi Chemical Society - May 16, 2019 Category: Chemistry Source Type: research
Synthesis of high-solid, low-viscosity hydroxy acrylic resin modified with TBCHA
Publication date: Available online 11 May 2019Source: Journal of Saudi Chemical SocietyAuthor(s): Xumeng Wang, Qunjie Xu, Haikun Yu, Jie XuAbstractHydroxyl acrylic resin using 4-tert-Butylcyclohexyl acrylate (TBCHA) as functional monomer has been synthesized via solution polymerization technique. Most critical experimental conditions have been optimized first by mixture experimental design methodology prior to real experiment operations. Afterward high-solid and low-viscosity hydroxy acrylic resin was synthesized under the optimized experimental conditions. According to a series of characterization methods including rheolo...
Source: Journal of Saudi Chemical Society - May 12, 2019 Category: Chemistry Source Type: research
CuSO4/Sodium ascorbate Catalyzed Synthesis of Benzosuberone and 1,2,3-triazole Conjugates: Design, Synthesis and in vitro Anti-Proliferative Activity
Publication date: Available online 11 May 2019Source: Journal of Saudi Chemical SocietyAuthor(s): CH.B. Praveena Devi, K. Vijay, B. Hari Babu, Syed Farooq Adil, M. Mujahid Alam, M. Vijjulatha, Mohd. Bismillah AnsariAbstractA novel series of conjugates of benzosuberone and 1,2,3-triazole i.e. 3-(4-phenyl-1H-1,2,3-triazol-1-yl)propyl-9-chloro-2,3-dimethyl-6,7-dihydro-5H-benzo[7] annulene-8-carboxylic acids (8a-j) were synthesized in good to excellent yields catalyzed by CuSO4 under milder reaction conditions and evaluated for their anti-proliferative activity. The structural elucidation of the prepared compounds was carried ...
Source: Journal of Saudi Chemical Society - May 12, 2019 Category: Chemistry Source Type: research
Mesopore-dominant porous carbon derived from bio-tars as an electrode material for high-performance supercapacitors
Publication date: Available online 6 May 2019Source: Journal of Saudi Chemical SocietyAuthor(s): Mi-Mi Wei, Wen-Ping Li, Jie Weng, Yun-Quan Liu, Shui-Rong Li, Yue-Yuan Ye, Meng Wang, Duo WangAbstractFor the first time, toxic bio-tars collected from the gasification of pine sawdust are used as the precursor for activated carbons. Various types of activation agents including KOH, K2CO3, H3PO4 and ZnCl2 were screened for obtaining superior activated carbons. When KOH was used as an activation agent, the obtained activated carbons exhibited high specific surface area and large mesopore volume. The activated carbons were furthe...
Source: Journal of Saudi Chemical Society - May 7, 2019 Category: Chemistry Source Type: research
Selective conversion of Furfuryl Alcohol to 2-methylfuran over Nanosilica supported Au:Pd bimetallic catalysts at room temperature
Publication date: Available online 6 May 2019Source: Journal of Saudi Chemical SocietyAuthor(s): Obaid Fahad Aldosari (Source: Journal of Saudi Chemical Society)
Source: Journal of Saudi Chemical Society - May 7, 2019 Category: Chemistry Source Type: research
Synthesis, spectral characterization, molecular docking studies, biological activity of (E)-2-((E)-3-(3,4,5-trimethoxyphenyl)allylidene) and (E)-N-phenyl 2-((E)-3-(3,4,5-trimethoxyphenyl)allylidene)hydrazinecarbothioamides and their Cu(II) complexes
Publication date: Available online 29 April 2019Source: Journal of Saudi Chemical SocietyAuthor(s): A. Sreenath Reddy, Jincheng Mao, S. Vanitha, Vishnu Nayak Badavath, L. Sivarama KrishnaAbstractTwo slightly distorted octahedral complexes of copper(II) with (E)-2-((E)-3-(3,4,5-trimethoxyphenyl)allylidene)hydrazinecarbothioamide (L1) common name 3,4,5-trimethoxy-cinnamaldehydethiosemicarbazone and (E)-N-phenyl-2-((E)-3-(3,4,5-trimethoxyphenyl)-allylidene)hydrazinecarbothioamide (L2) common name 3,4,5-trimethoxycinnamaldehyde-4-phenylthiosemicarbazone have been synthesized. The two free ligands and their copper(II) complexes...
Source: Journal of Saudi Chemical Society - April 30, 2019 Category: Chemistry Source Type: research
Editorial Board
Publication date: May 2019Source: Journal of Saudi Chemical Society, Volume 23, Issue 4Author(s): (Source: Journal of Saudi Chemical Society)
Source: Journal of Saudi Chemical Society - April 26, 2019 Category: Chemistry Source Type: research
Methodologies for the Synthesis of Pentacene and Its Derivatives
Publication date: Available online 13 April 2019Source: Journal of Saudi Chemical SocietyAuthor(s): Rohit Bhatia, Durgesh Wadhaw, Gargi Gurtu, Jitender Gaur, Deepak GuptaAbstractIn recent years, due to its high hole-mobility, high on/off current ratio and low threshold voltage, pentacene and its derivatives have found increasing application in the fabrication of light-emitting diodes, field-effect transistors, and photovoltaic cells. It has also emerged as an alternative to silicon due to its similar performance to inorganic semiconductors. Pentacene cannot be isolated from the petroleum fractions like other acenes such as...
Source: Journal of Saudi Chemical Society - April 14, 2019 Category: Chemistry Source Type: research
Steam reforming of toluene as model of tar compound over mo catalysts derived from hydrotalcites
This study evaluated the catalytic activity of Mo catalysts derived from hydrotalcite-like compounds for steam reforming of toluene as a model compound for tar. The catalysts with 1.5, 3 and 4.5 Mo loadings (wt %), denoted as Mo1.5MgAl, Mo3MgAl and Mo4.5MgAl respectively, were prepared by coprecipitation and characterized by BET, XRD, SEM, TEM, FT-IR and UV-VIS. The results showed that toluene conversion increased with increasing of molybdenum content. The hydrogen amount depended on two factors: the presence of molybdate species on the surface and the presence of aluminum cations in tetrahedral sites (Mo3MgAl), with molyb...
Source: Journal of Saudi Chemical Society - April 14, 2019 Category: Chemistry Source Type: research
Spectroscopic and Biological Properties of Platinum Complexes Derived From 2-Pyridyl Schiff Bases
Publication date: Available online 23 March 2019Source: Journal of Saudi Chemical SocietyAuthor(s): Nada D. Al-Khathami, Kamelah S. Al-Rashdi, Bandar A. Babgi, Mostafa A. Hussein, Muhammad Nadeem Arshad, Naser E. Eltayeb, Sobhy E. Elsilk, Jamal Lasri, Amal S. Basaleh, Mutlaq Al-JahdaliAbstractThe reactions of a range of aromatic primary amines with pyridine-2-carboxaldehyde were reported, highlighting the effect of the substituents of the amine on the outcomes of the Schiff base reactions. The variant products of the Schiff base reactions were reacted with cis-[PtCl2(DMSO)2], generating platinum(II) complexes with PtCl2(N^...
Source: Journal of Saudi Chemical Society - March 24, 2019 Category: Chemistry Source Type: research
Synthesis, structure, photophysical properties and biological activity of a cobalt(II) coordination complex with 4,4′-bipyridine and porphyrin chelating ligands
Publication date: Available online 23 March 2019Source: Journal of Saudi Chemical SocietyAuthor(s): Nesrine Amiri, Sahar Nouir, Melek Hajji, Thierry Roisnel, Taha Guerfel, Gérard Simonneaux, Habib NasriAbstractA new bioactive material of cobalt(II) with 5,10,15,20-tetrakis[4 (benzoyloxy)phenyl] porphyrin (TPBP) and bpy ligands ([CoII(TPBP)(bpy)2] 1) has been synthesised and characterized by Single-crystal X-ray diffraction (SCXRD), spectroscopic methods and quantum-chemistry calculations. In the crystalline structures of six coordinated Co(II) [CoII(TPBP)(bpy)2] 1, linear 1D polymeric chains were observed in which all the...
Source: Journal of Saudi Chemical Society - March 24, 2019 Category: Chemistry Source Type: research
Unsymmetrically substituted benzimidazolium based Silver(I)-N-Heterocyclic carbene complexes: Synthesis, Characterization and In vitro Anticancer study against Human Breast Cancer and Colon cancer
Publication date: Available online 23 March 2019Source: Journal of Saudi Chemical SocietyAuthor(s): Aqsa Habib, Mansoureh Nazrai Vishkaei, Muhammad Adnan Iqbal, Haq Nawaz Bhatti, M.B. Khadeer Ahmed, A.M.S. Abdul MajidAbstractThe promising biomedical applications of silver complexes stimulated the researchers to test these compounds against cancer. The present research work was designed to achieve this goal. In this work, a series of 5-methyl benzimidazole based N-Heterocyclic carbene ligands and respective silver(I) complexes were synthesized and tested on cancer cell lines to assess their anticancer activity. Unsymmetrica...
Source: Journal of Saudi Chemical Society - March 24, 2019 Category: Chemistry Source Type: research
