Starch nanoparticles as a bio-nanocatalyst in synthesis of diheteroaryl thioethers

Publication date: Available online 16 May 2019Source: Journal of Saudi Chemical SocietyAuthor(s): Homeyra Rostami Monjezi, Zohre Zarnegar, Javad SafariAbstractNanostarch is shown to be a highly efficient, eco-friendly and heterogenouse organocatalyst for the synthesis of the diheteroaryl thioethers via one-pot reaction of methylcarbonyls, thiourea and iodine in DMSO. This method offers significant advantages such as available starting materials, higher purity and excellent yield of products, very easy reaction conditions and absence of any tedious purification. Furthermore, because of employing eco-friendly catalyst without using transition metal catalysts, this novel method emerges as a green-approach leading to less harmful residues. Moreover, a mechanism was proposed to rationalize the reaction and the role of starch nanoparticles was also investigated in these transformations.
Source: Journal of Saudi Chemical Society - Category: Chemistry Source Type: research