The role of Phosphatidylinositol 3 kinase (PI3K) and Cycloxygenase-2 (COX2) in carcinogenesis of colorectal polyps
ConclusionsThe greater expression of the proliferation marker and Phosphatidylinositol 3 kinase in the right colon may be related to right-sided colorectal carcinogenesis. The proliferation marker, Cycloxygenase-2 and Phosphatidylinositol 3 kinase results can be associated with progression of polyps to colorectal cancer. The higher Phosphatase and tensin homolog expression suggests its attempt to control the cell cycle.ResumoObjetivosDeterminar a expressão imuno-histoquímica de Fosfatase homóloga a tensina (PTEN), Fosfatidilinositol-3-cinase (PI3K), Ciclooxigenase-2 (COX2) e um marcador de proliferação (Ki67) em póli...
Source: Journal of Coloproctology - July 10, 2018 Category: Gastroenterology Source Type: research
Association of sociodemographic and clinical factors with self-image, self-esteem and locus of health control in patients with an intestinal stoma
ConclusionsOstomized patients presented alterations in the following variables: unemployed, retired, aged up to 50 years and unmarried. There were also alterations in individuals whose cause of the stoma was neoplasia, a temporary stoma, stoma time <4 years, and ostomized non-participants of an association or support group, and who also did not practice physical activities. We conclude from these findings that ostomized individuals who participated in the study and who were included in these variables showed negative feelings about their body and believed that only they could control their health and that the people in...
Source: Journal of Coloproctology - July 10, 2018 Category: Gastroenterology Source Type: research
Screening anal cancer in women living with HIV/AIDS
ConclusionStudies have pointed out that there is concern about high anal cancer and anal HPV infection rates. They also highlighted the importance of the screening procedure for anal cancer prevention through cytology associated, or not, with molecular HPV detection methods.ResumoObjetivoAbordar as principais metodologias que podem ser utilizadas para o rastreamento do câncer anal em mulheres vivendo com HIV/AIDS, que têm sido publicadas atualmente na literatura científica.MetodologiaTrata-se de uma revisão integrativa de literatura, realizada através de pesquisa de artigos nas bases de dados PUBMED, EBSCO e LILACS, p...
Source: Journal of Coloproctology - July 10, 2018 Category: Gastroenterology Source Type: research
Appendectomy and Crohn's Disease
ConclusionThe appendix is important for intestinal homeostasis, preventing the development of certain pathologies. Its resection, regardless of whether or not there is an inflammation after surgery, increases the risk of Crohn's Disease and worsens the prognosis of this pathology, so appendectomy should be avoided in the absence of appendicitis.ResumoIntroduçãoA Doença de Crohn é um processo inflamatório crónico e idiopático com atingimento transmural que pode afetar todo o trato gastrointestinal. A etiopatogenia desta patologia não está completamente esclarecida pelo que se tem vindo a realizar estudos para perce...
Source: Journal of Coloproctology - July 10, 2018 Category: Gastroenterology Source Type: research
Colonic phytobezoar
Publication date: Available online 28 February 2018Source: Journal of ColoproctologyAuthor(s): Cláudio Franco do Amaral Kfouri, Maria Clara Ferreira Nonato Romania, Rennan Josely Moreira Julião, André Domingos Pippa Tomazella, Guilherme Paulo Carvalho de Amorim, Cleibe Nicácio da Silva, Claudinei da Silva, Maria Cristina SartorAbstractBezoars, although rare, represent a small part of the etiologies of intestinal obstructions. They are indigestible masses formed in human beings consisting of hair, seeds, plant fibers, fruits, and even medications. The present report concerns a male patient with a complaint of interrupte...
Source: Journal of Coloproctology - July 10, 2018 Category: Gastroenterology Source Type: research
A double row epiploicoplasty for primary closure of free perforated sigmoid diverticulitis
Publication date: Available online 21 March 2018Source: Journal of ColoproctologyAuthor(s): Ali Naki YücesoyAbstractAcute free perforation of the sigmoid diverticulitis is an emergency surgical intervention required condition. Although the sigmoid resection and temporary end colostomy or abdominal lavage and drainage are the most commonly used surgical methods for its treatment, the most effective surgical method has not been established yet. We applied a different surgical method for the surgical treatment of free perforation of acute sigmoid diverticulitis outside of these surgical procedures. A double row epiploicoplas...
Source: Journal of Coloproctology - July 10, 2018 Category: Gastroenterology Source Type: research
Hemorrhoids and related complications in primigravid pregnancy
ConclusionVarious risk factors and biological explanations exist for the high frequency of hemorrhoids during pregnancy. Because participants were primigravid women without a history of perianal complaints, findings suggest a direct effect of pregnancy itself on the development of external hemorrhoids/perianal symptoms.ResumoObjetivoIdentificar o efeito da gestação sobre o desenvolvimento de hemorroidas externas e obstipação.Indivíduos e métodosEste estudo piloto envolveu 61 mulheres primigestas sem história de doenças perianais. Cada paciente foi examinada e preencheu um questionário entre a 11ª e a 14ª semanas...
Source: Journal of Coloproctology - July 10, 2018 Category: Gastroenterology Source Type: research
Intestinal preparations for colonoscopy. Comparative study: mannitol, picosulphate and macrogol
This study aimed to compare three solutions for colon preparation in patients undergoing colonoscopy. We conducted a prospective study with 61 patients divided randomly into three groups: one that received a standard dose of macrogol, another received a standard dose of 10% mannitol and another received a standard dose of sodium picosulphate. Patients and examining endoscopists responded to questionnaires for compiling data. In the results we noticed that 10% mannitol, despite being less tolerated by the patient when compared to sodium picosulphate, presents better results in colonic cleaning, being therefore superior in t...
Source: Journal of Coloproctology - July 10, 2018 Category: Gastroenterology Source Type: research
Evaluation of outcomes in fissurectomy and V–Y advancement flap for the treatment of chronic anal fissure
Publication date: April–June 2018Source: Journal of Coloproctology, Volume 38, Issue 2Author(s): Fakhrosadat Anaraki, Tahereh Foroughifar, Seyed Hossein Laleh, Omid EtemadAbstractChronic anal fissure is difficult to treat. Surgery is usually recommended in the case of drug therapeutic failure. Fecal incontinence in patients with weaker sphincters (multipara older patients with a history of pelvic surgery etc.) is a major reason for rejecting surgery. Such these patients should be underwent fissurectomy and V–Y advancement flap in which sphincterotomy is not required. In this prospective study, we determined the outcome...
Source: Journal of Coloproctology - July 10, 2018 Category: Gastroenterology Source Type: research
Surgical and oncological short-term outcomes of prone extralevator abdominoperineal excision for low rectal cancer
ConclusionProne extralevator abdominoperineal excision is comparable to standard abdominoperineal resection. It was associated to a decrease in length of hospital stay and readmission rate, although more perineal complications occurred. We cannot recommend it as a standard technique for all low rectal cancer. Notwithstanding, prone extralevator abdominoperineal excision can be considered a more radical approach when there is sphincter complex or levators muscles invasion.ResumoIntroduçãoNos últimos anos, foi proposta e adotada em muitos centros uma abordagem cirúrgica padronizada para o câncer retal baixo (CRB). A exc...
Source: Journal of Coloproctology - July 10, 2018 Category: Gastroenterology Source Type: research
Interrelation between functional constipation and domestic violence
ConclusionThe prevalence of domestic violence in women with functional constipation is high and a careful investigation of this possible interrelationship in clinical practice is suggested. Besides that, it is necessary to promote an integration of the Network of Attention to Violence, in order to offer integral care to the victims and a best utilization of the resources.ResumoIntroduçãoOs distúrbios funcionais do aparelho digestivo são frequentemente relacionados a diversas formas de abuso e a abordagem integral do problema requer uma rede multidisciplinar de cuidados. Os objetivos deste estudo foram: avaliar a preval...
Source: Journal of Coloproctology - July 10, 2018 Category: Gastroenterology Source Type: research
Lessons from the first 70 patients operated by doppler-guided haemorrhoidal artery ligation with mucopexy in a French team specialising in surgical proctology
ConclusionDoppler-guided haemorrhoidal artery ligation with mucopexy is an effective technique in the medium-term. Good tolerance in makes this treatment an attractive alternative to conventional haemorrhoidectomy.ResumoExperiênciaA ligação de artéria hemorroidária com mucopexia orientada por Doppler é técnica cirúrgica minimamente invasiva. Esse procedimento é efetivo e menos doloroso do que a hemorroidectomia convencional.MétodosReunimos os prontuários de todos os pacientes operados entre novembro de 2012 e junho de 2014. Foram calculados escores pré-operatórios e pós-operatórios durante as consultas e, em...
Source: Journal of Coloproctology - July 10, 2018 Category: Gastroenterology Source Type: research
Current management of spontaneous intra-abdominal abscess in Crohn's disease
Publication date: April–June 2018Source: Journal of Coloproctology, Volume 38, Issue 2Author(s): Ana Teresa Pugas Carvalho, Barbara Cathalá Esberard, Andre da Luz MoreiraAbstractCrohn's disease (CD) is a chronic transmural disease process with approximately 10% of patients developing spontaneous intra-abdominal abscess during the first 5 years after the diagnosis. The symptoms are often nonspecific. The treatment modalities include the use of wide-spectrum antibiotics, imaging-guided percutaneous drainage (PD) and surgical drainage with or without resection. The best initial treatment strategy has not been settled contr...
Source: Journal of Coloproctology - July 10, 2018 Category: Gastroenterology Source Type: research
Pseudomyxoma peritonei originating from appendix tumors
ConclusionDespite the great progress we have witnessed in recent years, which have led to a large increase in survival rates, more research needs to be done, on what to do when the disease is in an unresectable stage. Finding a less aggressive therapy than cytoreductive surgery + hyperthermic intraperitoneal chemotherapy will be an important step forward.ResumoIntroduçãoAs neoplasias do apêndice são bastante raras, representando atualmente cerca de 1% de todas as neoplasias gastrointestinais. O adenocarcinoma mucinoso é um dos subtipos de neoplasia do apêndice e caracteriza-se por metastizar para o peritone...
Source: Journal of Coloproctology - July 10, 2018 Category: Gastroenterology Source Type: research
Deficiency of vitamin D and its relation with clinical and laboratory activity of inflammatory bowel diseases
ConclusionAccording to the findings of this study, vitamin D deficiency is related to the clinical and laboratory activity of inflammatory bowel diseases.ResumoObjetivoAvaliar as concentrações séricas de vitamina D e sua relação com as doenças inflamatórias intestinais.MétodosEstudo quantitativo e descritivo com indivíduos assistidos pelo ambulatório interdisciplinar de Doença Inflamatória Intestinal da Unidade de Saúde Familiar e Comunitária de Itajaí/SC no período de setembro 2015 até outubro 2016. Foram coletados dados socioeconômicos, hábitos de vida, exames bioquímicos e foram plicados os índices ...
Source: Journal of Coloproctology - July 10, 2018 Category: Gastroenterology Source Type: research
