Lumbar Spine Trabecular Bone Score (TBS) Reflects Diminished Bone Quality in Patients With Diabetes Mellitus and Oral Glucocorticoid Therapy
The objective of this study was to determine whether TBS is a better clinical tool than traditionally used bone mineral density (BMD) to detect the skeletal deterioration seen in patients with diabetes (DM), patients undergoing oral glucocorticoid (GC) therapy, and patients who are both diabetic and taking steroids (GC  + DM). (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - November 1, 2017 Category: Radiology Authors: Yunfeng Xue, Andrea L. Baker, Shahla Nader, Philip Orlander, Anthony J. Sanchez, James Kellam, Nahid J. Rianon, Catherine G. Ambrose Tags: Original Article Source Type: research

Cumulative Effective Dose and Cancer Risk of Pediatric Population in Repetitive Whole-Body Scan Using Dual-Energy X-Ray Absorptiometry
This study aims to quantitatively evaluate the cumulative effective dose and associated cancer risk of pediatric patients of US and Hong Kong population undergoing repetitive whole-body scans with dual-energy X-ray absorptiometry (DXA) during their diagnosis and follow-up periods. Organ-absorbed doses of pediatric patients undergoing DXA whole-body scan have been computer simulated using patient imaging parameters input to the Monte Carlo software PCXMC. Gender- and age-specific effective doses have been calculated with the simulated organ-absorbed doses using the ICRP-103 approach. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - October 27, 2017 Category: Radiology Authors: Martin Law, Wang-Kei Ma, Eva Chan, Candy Mui, Vivian Ma, Wai-Yin Ho, Lawrance Yip, Wendy Lam Source Type: research

Bone Geometric Properties of the Femoral Neck in Underweight Eumenorrheic Women
The aim of this study was to describe femoral neck (FN) geometry among eumenorrheic underweight women around the age of peak bone mass. Proximal femur geometry and body composition were assessed in 12 underweight women and in 24 healthy controls using dual-energy X-ray absorptiometry. The Hip Structural Analysis program was used to determine bone geometry at the FN. The cross-sectional area (CSA) and the cross-sectional moment of inertia (CSMI) were significantly lower in underweight women than in controls (p   (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - October 19, 2017 Category: Radiology Authors: Nathalie Al Rassy, Joseph Matta, Fabienne Frenn, Ghassan Maalouf, Maroun Rizkallah, Falah Bachour, Amer Sebaaly, Pierre Hardouin, Christophe Chauveau, Rawad El Hage Tags: Original Article Source Type: research

The Influence of Reconstruction Kernel on Bone Mineral and Strength Estimates Using Quantitative Computed Tomography and Finite Element Analysis
We examined the influence of computed tomography convolution back-projection reconstruction kernels on the analysis of bone quantity and estimated mechanical properties in the proximal femur. Eighteen computed tomography scans of the proximal femur were reconstructed using both a standard smoothing reconstruction kernel and a bone-sharpening reconstruction kernel. Following phantom-based density calibration, we calculated typical bone quantity outcomes of integral volumetric bone mineral density, bone volume, and bone mineral content. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - October 17, 2017 Category: Radiology Authors: Andrew S. Michalski, W. Brent Edwards, Steven K. Boyd Source Type: research

Do Textiles Impact DXA Bone Density or Body Composition Results?
External artifacts can confound dual-energy X-ray absorptiometry (DXA) measurements. It is often accepted that garments free of metal do not affect DXA results; however, little data exist in this regard. It is plausible that some textiles absorb radiation and thereby alter DXA results. We hypothesized that some dense or synthetic textiles, for example, reflective materials, might alter DXA-measured bone and soft tissue mass. Hologic and GE Lunar spine phantoms and a Bioclinica prototype total body phantom were imaged on a GE Lunar iDXA and Prodigy densitometer. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - October 6, 2017 Category: Radiology Authors: E. Siglinsky, N. Binkley, D. Krueger Source Type: research

Empowering the Patient While Developing an Osteoporosis Management Strategy
The past 2 decades have witnessed the introduction of several effective medications to reduce the fracture risk of patients with osteoporosis. We also have the means of estimating the individual patient's probability of sustaining osteoporotic fractures and therefore we can identify patients at risk of sustaining fractures before they sustain these fractures. In other words, we are now able to target therapy to those who need it most because their fracture risk is elevated, and avoid treating patients whose fracture risk is not elevated. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - October 1, 2017 Category: Radiology Authors: Ronald C. Hamdy Source Type: research

Reversing the Relationship Between Dual-Energy X-ray Absorptiometry and the 4-Component Model With 1 Sign Flip
We thoroughly enjoyed reading the recent JCD article “An Investigation Into the Differences in Bone Density and Body Composition Measurements Between 2 GE Lunar Densitometers and Their Comparison with a 4-Component Model” from Watson et al (1). We commend the authors for an interesting and practical study comparing dual-energy X-ray absorptiometr y (DXA) body composition measurements to a gold-standard 4-component (4-C) model. Watson and colleagues found “a significant difference between 4-C-derived fat mass (FM) and [all DXA FM measurements]” ranging from −0.936 to −2.157 kg. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - September 28, 2017 Category: Radiology Authors: Bennett K. Ng, Markus J. Sommer, John A. Shepherd Tags: Letter to the Editor Source Type: research

Evaluation of Different Screening Tools for Predicting Femoral Neck Osteoporosis in Rural South Indian Postmenopausal Women
This study was done to assess the diagnostic performance of 6 internationally validated tools (Simple Calculated Osteoporosis Risk Estimation [SCORE], age, bulk, one or never estrogen [ABONE ], Osteoporosis Risk Assessment Instrument [ORAI] and Osteoporosis Self-Assessment Tool for Asians [OSTA], Fracture Risk Assessment Tool [FRAX®], and calcaneal quantitative ultrasound [QUS]) for the diagnosis of osteoporosis at the femoral neck (FN). (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - September 25, 2017 Category: Radiology Authors: Kripa Elizabeth Cherian, Nitin Kapoor, Sahana Shetty, Dukhabandhu Naik, Nihal Thomas, Thomas V. Paul Tags: Original Article Source Type: research

Quantitative Ultrasound of the Mandible as a Novel Screening Approach for Osteoporosis
This study used an axial transmission quantitative ultrasound (QUS) device to assess mandibular bone strength. The aim of the study was first to establish the precision and repeatability of the axial transmission QUS measurement for a range of mandibular anatomic sites, and second to investigate the ability of the modality to differentiate between osteoporotic subjects and a control group. Three groups of adult Caucasian women were recruited: (1) healthy premenopausal women (n  = 26), (2) healthy postmenopausal women (n = 48), and (3) women with osteoporosis (n = 53). (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - September 21, 2017 Category: Radiology Authors: Anna Beattie, Se án Cournane, Ciarán Finucane, J. Bernard Walsh, Leo F.A. Stassen Tags: Original Article Source Type: research

Bone Remodeling of the Distal Femur After Uncemented Total Knee Arthroplasty —A 2-Year Prospective DXA Study
This study investigates the adaptive bone remodeling of the distal femur after uncemented total knee arthroplasty. We performed a 2-year follow-up of 53 patients (mean age 61.5 [38 –70] years, F/M = 27/26, body mass index 29.5) who because of osteoarthritis received an uncemented total knee arthroplasty. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - September 13, 2017 Category: Radiology Authors: Mikkel Rathsach Andersen, Nikolaj S. Winther, Thomas Lind, Henrik M. Schr øder, Michael Mørk Petersen Source Type: research