Role of a High Risk Osteoporosis Consult (HiROC) Service in Patients with Hip Fractures in the Inpatient and Post-Discharge Setting
Introduction: Osteoporosis and associated fractures are medical conditions with substantial morbidity and mortality. Because these are highly preventable conditions, the widespread adoption and implementation of quality metrics have created pressures on hospitals to improve delivery and quality of care. Several healthcare systems in the USA have developed promising programs to address these metrics. However there have been few studies that look at the role of a fracture liaison inpatient service as a bridge to continued therapy in the post-discharge setting. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - January 1, 2018 Category: Radiology Authors: M. Ismaily, U. Gruntmanis Source Type: research
Relationship between DXA-Based Visceral Fat and Other Total Body and Regional Fat Assessments
Studies have suggested that how fat is distributed –especially fat distribution within the abdomen– in the body may aid is assessing individual risk to subjects. The current study evaluates the utility of applying the DXA study to this purpose by examining the relationship between regional and total DXA-based fat content and anthropometrically o r MRI assessed total body or abdominal fat content. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - January 1, 2018 Category: Radiology Authors: Jingmei Wang, Yun Sun, Chad Dudzek, Tom Sanchez Source Type: research
Validation of In Vivo Vertebral Fracture Assessment Using the Norland Illuminatus Software
A semiquantitative evaluation of the T9-L4 vertebral column by DXA evaluation of vertebral fracture has been proposed, alongside traditional DXA, as a complimentary reflector of osteoporotic risk that may be useful in bringing some subjects to treatment. The current study seeks to document the performance of the Norland Vertebral Fracture Assessment Module by comparison to a radiographically determined vertebral fracture assessment and by assessing repeatability of the DXA assessed vertebral fracture assessment. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - January 1, 2018 Category: Radiology Authors: Yun Sun, Jingmei Wang, Thomas Thuring, Tom Sanchez Source Type: research
Feasibility Study of Quality Control Methodology for TBS
Objective: The aim of this study is to develop a TBS Quality Control (QC) methodology using the new TBS phantom. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - January 1, 2018 Category: Radiology Authors: F. Michelet, D. Krueger, N. Binkley Source Type: research
TBS Association with Biomechanical Properties of Human Vertebrae, Ex-Vivo
Objective: The clinical utility of Trabecular Bone Score (TBS) to evaluate the risk for osteoporotic fracture has been widely recognized by the scientific community. To date only one study presented data on the relation between TBS and bone mechanical properties, with a relatively small sample size. The aim of this study was to evaluate the relationship between TBS, BMD and mechanical properties of on a larger sample of human vertebra ex vivo. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - January 1, 2018 Category: Radiology Authors: D. Tran, F. Michelet, C. Lelong, D. Hans Source Type: research
Quantification of the Effects of Soft Tissues on the Experimental Variogram, the Basic Algorithm of TBS
Purposes: TBS is derived from the initial slope of the log-log experimental variogram of the DXA bone image, and the TBS computation process includes a soft tissue compensation. The aim of this study is to quantify the influence of soft tissues on the variogram, and provide background information on how tissues could influence TBS, to better implement corrective adjustments if necessary. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - January 1, 2018 Category: Radiology Authors: F. Michelet, D. Hans Source Type: research
Tracking of Spine BMD (Bone Mineral Density) in Infants Exposed to TDF (Tenofovir Disproxil Fumarate) Medication in Utero and/or during Breast Feeding
Background: Tracking bone mineral density (BMD) over time can is useful to monitor bone development in growing bones. Dual-energy X-ray absorptiometry (DXA) is an ideal method for children because of its low radiation dose. However, movement during scans is a problem. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - January 1, 2018 Category: Radiology Authors: L. Kazemi, B. Fan, M. Sommer, K. George, L. Stranix-Chibanda, J. Shepherd Source Type: research
Validation of Body Composition Measures From Forearm and Lateral Distal Femur Scans of Children
Background: Measuring body composition by dual-energy x-ray absorptiometry (DXA) at regional locations is feasible and may be useful in very young children when whole body scans are impractical. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - January 1, 2018 Category: Radiology Authors: N. Din, B. Fan, L. Kazemi, B. Ng, A.P. Mahmoudzadeh, B.S. Zemel, H.J. Kalkwarf, J. Shepherd Source Type: research
Professional Athletes with Fractures May Have a “Degraded” Trabecular Bone Score (TBS)
Since the 2000 NIH Consensus Conference, the relationship that Bone Strength = Bone Quality + Bone Density has been utilized in understanding skeletal resistance to fracture. Many elite athletes suffer fractures, predominantly acute traumatic or stress; many suffer recurrences. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - January 1, 2018 Category: Radiology Authors: Clinten P. Edmondson, Christelle Domantay, Patricia E. Schwartz, Elliott N. Schwartz Source Type: research
Appendicular Intracellular Water Index Measured by Bioelectric Impedance Spectroscopy (BIS) as a Potential Surrogate for DXA-Measured Appendicular Lean Mass
Introduction: Proposed consensus definitions of sarcopenia include lean mass measurement; thus generally requiring a whole body DXA. As this is not available everywhere and is not portable, there are situations where sarcopenia assessment is impractical. Consequently, we evaluated the potential of a mobile tool, bioelectric impedance spectroscopy (BIS), to assess muscle mass for sarcopenia determination. We hypothesized that BIS-measured appendicular intracellular water index (as a surrogate for muscle mass) corrected by height (aICW/ht2) would correlate well with ALM/ht2 and potentially allow establishment of a sarcopenia...
Source: Journal of Clinical Densitometry - January 1, 2018 Category: Radiology Authors: E. Siglinsky, B. Buehring, D. Krueger, N. Binkley, Y. Yamada Source Type: research
Hologic Horizon Spine, Forearm and Lateral Distal Femur Precision in Young Children
Purpose: Precision characterization is vital to determine when significant changes in bone mineral density (BMD) and bone mineral content (BMC) have occurred as an individual is monitored over time. Precision can vary due to bone density, body size, system make and model, and technologist skill. We have previously presented that DXA precision estimates for infants and children ages 6 years to 16 years old. The purpose of this study was to evaluate the DXA precision error from multiple measurement sites of young children, from 1 to 3 years old. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - January 1, 2018 Category: Radiology Authors: Bo Fan, Natasha Din, Leila Kazemi, Heidi Kalkwarf, Babette Zemel, John A. Shepherd Source Type: research
3D Optical Models for Predicting Osteopenia, Sarcopenia, and Obesity Status in Women
Background: Sarcopenic obesity (OB-S) is a category of obesity in the elderly defined as excess adiposity with reduced muscle mass. OB-S increases the risk of fractures and falls in older individuals. However, three DXA scans are needed to determine muscle and bone status (whole body, hip, and spine). Furthermore, many obese patients are presumed to have high bone density due to the influence of high weight and may not be identified for any DXA scan. Whole body, three-dimensional optical (3DO) scanning is an automated, highly accessible technology shown to accurately predict fat and lean mass status. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - January 1, 2018 Category: Radiology Authors: E.Y. Liu, M. Sommer, B. Fan, B. Ng, J. Mastick, J.A. Shepherd Source Type: research
Impact of Very Dense Artifacts on Hologic and GE Lunar Densitometers
Introduction: Black hole-type artifacts have been described on Hologic densitometers from materials such as tantalum clips and lead bullets. Whether such artifacts occur on GE Healthcare scanners has not been reported. We hypothesized that black hole-type artifacts are specific to Hologic instruments. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - January 1, 2018 Category: Radiology Authors: S. Morgan, D. Krueger, L. Burroughs, N. Binkley Source Type: research
Osteoporosis: Heading Towards the Perfect Storm
Dark clouds are gathering on the horizon, gale force winds, soon to become hurricane level winds, are battering our shores. It is getting dark. We have no running water, no electricity and floods have blocked our escape route. We are heading towards the perfect storm. This nightmarish scenario is gradually but surely unfolding. We are heading, full speed ahead, in the wrong direction. Of course I am not talking about the weather, I am referring to osteoporosis, its detection, diagnosis, management and potential impact. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - January 1, 2018 Category: Radiology Authors: Ronald C. Hamdy Source Type: research
Bone Mineral Density of the Radius Predicts All-Cause Mortality in Patients With Type 2 Diabetes: Diabetes Heart Study
This study aimed to determine the association between areal and volumetric bone mineral density (BMD) with all-cause mortality in patients with type 2 diabetes (T2D). Associations between BMD and all-cause mortality were examined in 576 women and 517 men with T2D in the Diabetes Heart Study. Volumetric BMD in the thoracic and lumbar spine was measured with quantitative computed tomography. Areal BMD (aBMD) in the lumbar spine, total hip, femoral neck, ultradistal radius, mid radius, and whole body was measured using dual X-ray absorptiometry. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - December 25, 2017 Category: Radiology Authors: Leon Lenchik, Thomas C. Register, Fang-Chi Hsu, Jianzhao Xu, S. Carrie Smith, J. Jeffrey Carr, Barry I. Freedman, Donald W. Bowden Source Type: research
