Hematology Oncology and Stem Cell Therapy This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Phenotypic Characterization of Malignant Progenitor Cells in Patients with Idiopathic Myelofibrosis
ConclusionThese data indicate that IL-3Rαhigh CD34+ cells from IM enriched for the malignant progenitor cells and IL-3Rα/CD123 may be a potential biomarker and therapeutic target for IM. Our findings will be further validated in future studies with a larger sample size and serial transplant in murine models. (Source: Hematology Oncology and Stem Cell Therapy)
Source: Hematology Oncology and Stem Cell Therapy - February 21, 2019 Category: Cancer & Oncology Source Type: research

Graft-Versus-Host Disease of the Kidney
Publication date: Available online 20 February 2019Source: Hematology/Oncology and Stem Cell TherapyAuthor(s): Abhilash Koratala, Mark S Segal, Nosha Farhadfar, Xu Zeng (Source: Hematology Oncology and Stem Cell Therapy)
Source: Hematology Oncology and Stem Cell Therapy - February 21, 2019 Category: Cancer & Oncology Source Type: research

Prediction of Oncotype Dx Recurrence Score Using Clinical Parameters: A Comparison of Available Tools and a Simple Predictor Based on Grade and Progesterone Receptor
ConclusionThe simple GR-PR predictor proposed in this study seems to be at least as accurate as more complex tools and should be the preferred tool for the prediction of Oncotype Dx RS from clinicopathologic parameters when the Oncotype Dx test is not available. (Source: Hematology Oncology and Stem Cell Therapy)
Source: Hematology Oncology and Stem Cell Therapy - February 20, 2019 Category: Cancer & Oncology Source Type: research

Physical therapy pathway and protocol for patients undergoing hematopoietic stem cell transplantation: Recommendations from The Eastern Mediterranean Blood and Marrow Transplantation (EMBMT) Group
Publication date: Available online 11 January 2019Source: Hematology/Oncology and Stem Cell TherapyAuthor(s): Jaleel Mohammed, Mahmoud Aljurf, Abdulaziz Althumayri, Muntaha Almansour, Ahmed Alghamdi, Amir Ali Hamidieh, Alaa ElHaddad, Tarek Ben Othman, Ali Bazarbachi, Fahad Almohareb, Mohsen Alzahrani, Salam S. Alkindi, Fahad Alsharif, Waleed Da'na, Hani Alhashmi, Mohamed A. Bekadja, Salem H. Al-Shammari, Asma El Quessar, Tariq M. Satti, Naif AljohaniAbstractPatients undergoing hematopoietic stem cell transplantation (HSCT) are often referred for physical therapy (PT) to help improve their quality of life. However, to our k...
Source: Hematology Oncology and Stem Cell Therapy - January 15, 2019 Category: Cancer & Oncology Source Type: research

“Physical Therapy Pathway and Protocol for patients undergoing hematopoietic stem cell transplantation: Recommendations from The Eastern Mediterranean Blood and Marrow Transplantation (EMBMT) Group”
Publication date: Available online 11 January 2019Source: Hematology/Oncology and Stem Cell TherapyAuthor(s): Jaleel Mohammed, Mahmoud Aljurf, Abdulaziz Althumayri, Muntaha Almansour, Ahmed Alghamdi, Amir Ali Hamidieh, Alaa ElHaddad, Tarek Ben Othman, Ali Bazarbachi, Fahad Almohareb, Mohsen Alzahrani, Salam S. Alkindi, Fahad Alsharif, Waleed Da'na, Hani Alhashmi, Mohamed A. Bekadja, Salem H. Al-Shammari, Asma El Quessar, Tariq M. Satti, Naif AljohaniAbstractPatients undergoing HSCT are often referred for physical therapy (PT) to help improve their quality of life. However, to our knowledge there is no clear PT pathway to g...
Source: Hematology Oncology and Stem Cell Therapy - January 11, 2019 Category: Cancer & Oncology Source Type: research

The Strange Case of Dr. Hashmi and Mr. Hyde
Publication date: Available online 9 January 2019Source: Hematology/Oncology and Stem Cell TherapyAuthor(s): Shahrukh K. Hashmi (Source: Hematology Oncology and Stem Cell Therapy)
Source: Hematology Oncology and Stem Cell Therapy - January 10, 2019 Category: Cancer & Oncology Source Type: research

Low-dose Radiotherapy for Extranodal Marginal Zone B Lymphoma of the Lip: Case Report and Literature Review
We present a case report of a patient with extranodal NHL of the lip treated with chemotherapy and low-dose radiation treatment (RT). The patient was affected by B-cell NHL of the marginal zone, Stage IAE. After a few months of observation with this progressive disease, the patient was submitted to two cycles of chemotherapy with no response. Therefore, he was treated with very low-dose RT consisting of two fractions of 2 Gy. Complete response was observed and after 1-year follow-up, persistent complete response was recorded. In cases of localized disease, especially in patients with comorbidities of poor performance statu...
Source: Hematology Oncology and Stem Cell Therapy - January 1, 2019 Category: Cancer & Oncology Source Type: research

A Single-institution Experience of Performing Bloodless Transplant in Jehovah's Witness Patients
Publication date: Available online 27 December 2018Source: Hematology/Oncology and Stem Cell TherapyAuthor(s): Alexander Coltoff, Aditya Shreenivas, Solmaz Afshar, Amir SteinbergAbstractAutologous stem cell transplant has been shown to prolong survival in multiple myeloma (MM). A common complication of the pre-transplant conditioning chemotherapy is severe multi-lineage cytopenias, resulting in significant transfusion requirements. Jehovah's Witnesses are members of a religious group that do not accept the transfusion of blood products. Many large transplant centers refuse to perform transplantation in Jehovah's Witnesses ...
Source: Hematology Oncology and Stem Cell Therapy - December 28, 2018 Category: Cancer & Oncology Source Type: research

Epstein-Barr Viremia and Post-Transplant Lymphoproliferative Disorders in patients undergoing Haploidentical Stem Cell Transplantation with Post-Transplant Cyclophosphamide
Publication date: Available online 9 December 2018Source: Hematology/Oncology and Stem Cell TherapyAuthor(s): Ghulam Rehman Mohyuddin, John Roller, Leyla Shune, Tara Lin, Ajoy Dias, Siddhartha Ganguly, Sunil Abhyankar, Joseph McGuirk, Anurag Singh (Source: Hematology Oncology and Stem Cell Therapy)
Source: Hematology Oncology and Stem Cell Therapy - December 10, 2018 Category: Cancer & Oncology Source Type: research

Haploidentical Related Donor Allogeneic Hematopoietic Stem Cell Transplantation for Patient Aged Older Than 76 Years with Refractory Acute Myeloid Leukemia
Publication date: Available online 9 December 2018Source: Hematology/Oncology and Stem Cell TherapyAuthor(s): Jean El-Cheikh, Rana Salem, Radwan Massoud, Charelle Salem, Nohra Ghaoui, Souha S. Kanj, Rami Mahfouz, Ali Bazarbachi (Source: Hematology Oncology and Stem Cell Therapy)
Source: Hematology Oncology and Stem Cell Therapy - December 10, 2018 Category: Cancer & Oncology Source Type: research

Impact of Hospital Hospitality House Programs on Quality of Life and Mood of Patients and Caregivers after Hematopoietic Stem Cell Transplant
ConclusionEfforts to improve QOL30 of HSCT patients and caregivers in the confined environment of an HHH should focus on patients with low baseline QOL and older patients. (Source: Hematology Oncology and Stem Cell Therapy)
Source: Hematology Oncology and Stem Cell Therapy - December 10, 2018 Category: Cancer & Oncology Source Type: research

Ki-67 Labeling Index in Glioblastoma; Does it Really Matter?
ConclusionThe difference between the survival curves of patients with Ki-67 labeling index of ≤ 27%, and Ki-67 of> 27% was statistically insignificant (p = .130). Therefore, Ki-67 labeling index alone cannot predict survival in glioblastoma patients. (Source: Hematology Oncology and Stem Cell Therapy)
Source: Hematology Oncology and Stem Cell Therapy - December 8, 2018 Category: Cancer & Oncology Source Type: research

Impact of CD39 Expression on CD4+ T Lymphocytes and 6q Deletion on Outcome of Patients With Chronic Lymphocytic Leukemia
ConclusionCD39 expression on CD4+Tcells and del 6q act as prognostic markers in CLL. Blocking or inhibition of CD39 may be a target for new immune therapy for CLL. (Source: Hematology Oncology and Stem Cell Therapy)
Source: Hematology Oncology and Stem Cell Therapy - October 12, 2018 Category: Cancer & Oncology Source Type: research

Cutaneous light chain amyloidosis with multiple myeloma: A concise review
ConclusionsWe reviewed the constellation of the cutaneous manifestations of AL amyloidosis with concurrent MM. We found a female predominance, and more than half presented as hemorrhagic bullous lesions. There is a preponderance of λ light chains over kappa (κ) light chains, both as a free light chain (15% vs. 4%) and as an intact Ig (38% vs. 24%; absolute number of 14 vs. 7 patients, respectively). In the subgroup of patients with bullous skin lesions, λ light chain was present in eight cases and κ light chain in seven cases. All κ light chain subtypes presented with bullous lesions and no other cutaneous types of le...
Source: Hematology Oncology and Stem Cell Therapy - October 4, 2018 Category: Cancer & Oncology Source Type: research

Early posttraumatic changes in coagulation and fibrinolysis systems in isolated severe traumatic brain injury patients and its influence on immediate outcome
ConclusionIncidence of TIC in iSTBI is 41.6%, with 4.7 times odds for mortality. Traumatic brain injury causes enhanced coagulation activation, inadequate inhibition, exacerbation of thrombin generation, and subsequent increased fibrinolysis. ROC curve analysis revealed a cut-off of PS ≤ 74 with specificity 63.8%, sensitivity 72.7% for development of TIC. (Source: Hematology Oncology and Stem Cell Therapy)
Source: Hematology Oncology and Stem Cell Therapy - October 4, 2018 Category: Cancer & Oncology Source Type: research