Depression and stress levels increase risk of liver cancer through epigenetic downregulation of hypocretin
Publication date: Available online 2 December 2020Source: Genes & DiseasesAuthor(s): Chunyun Pu, Shaorong Tian, Sanxiu He, Weihong Chen, Yuanyuan He, Hongyan Ren, Jing Zhu, Jun Tang, Xiaolan Huang, Ying Xiang, Yixiao Fu, Tingxiu Xiang (Source: Genes and Diseases)
Source: Genes and Diseases - December 3, 2020 Category: Genetics & Stem Cells Source Type: research

Development of a multicellular 3D-bioprinted microtissue model of human periodontal ligament-alveolar bone biointerface: Towards a pre-clinical model of periodontal diseases and personalized periodontal tissue engineering
Publication date: Available online 28 November 2020Source: Genes & DiseasesAuthor(s): Murat Taner Vurat, Şükran Şeker, Özge Lalegül-Ülker, Mahmut Parmaksiz, Ayşe Eser Elçin, Yaşar Murat Elçin (Source: Genes and Diseases)
Source: Genes and Diseases - November 30, 2020 Category: Genetics & Stem Cells Source Type: research

Lack of endothelial DLC1 does not compromise liver and kidney function in mice
Publication date: Available online 28 November 2020Source: Genes & DiseasesAuthor(s): Ying Tan, Su Hao Lo (Source: Genes and Diseases)
Source: Genes and Diseases - November 30, 2020 Category: Genetics & Stem Cells Source Type: research

NADPH debt drives redox bankruptcy: SLC7A11/xCT-mediated cystine uptake as a double-edge sword in cellular redox regulation
Publication date: Available online 25 November 2020Source: Genes & DiseasesAuthor(s): Xiaoguang Liu, Yilei Zhang, Li Zhuang, Kellen Olszewski, Boyi Gan (Source: Genes and Diseases)
Source: Genes and Diseases - November 25, 2020 Category: Genetics & Stem Cells Source Type: research

The mevalonate pathway promotes the metastasis of osteosarcoma by regulating YAP1 activity via RhoA
Publication date: Available online 21 November 2020Source: Genes & DiseasesAuthor(s): Xing Du, Yunsheng Ou, Muzi Zhang, Kai Li, Wei Huang, Dianming Jiang (Source: Genes and Diseases)
Source: Genes and Diseases - November 22, 2020 Category: Genetics & Stem Cells Source Type: research

Sulfuretin exerts diversified functions in the processing of amyloid precursor protein
Publication date: Available online 21 November 2020Source: Genes & DiseasesAuthor(s): Jian Chen, Biao Luo, Bi-Rou Zhong, Kun-Yi Li, Qi-Xin Wen, Li Song, Xiao-Jiao Xiang, Gui-Feng Zhou, Li-Tian Hu, Xiao-Juan Deng, Yuan-Lin Ma, Guo-Jun Chen (Source: Genes and Diseases)
Source: Genes and Diseases - November 22, 2020 Category: Genetics & Stem Cells Source Type: research

Ubiquitin ligase DTX3 empowers mutant p53 to promote ovarian cancer development
Publication date: Available online 21 November 2020Source: Genes & DiseasesAuthor(s): Shanshan Wang, Qian Hao, Jiajia Li, Yajie Chen, Hua Lu, Xiaohua Wu, Xiang Zhou (Source: Genes and Diseases)
Source: Genes and Diseases - November 21, 2020 Category: Genetics & Stem Cells Source Type: research

Patients with SARS-CoV-2 and HBV co-infection are at risk of greater liver injury
Publication date: Available online 18 November 2020Source: Genes & DiseasesAuthor(s): Yong Lin, Jun Yuan, Quanxin Long, Jieli Hu, Haijun Deng, Zhenyu Zhao, Juan Chen, Mengji Lu, Ailong Huang (Source: Genes and Diseases)
Source: Genes and Diseases - November 18, 2020 Category: Genetics & Stem Cells Source Type: research

Cyclin G2, a novel target of sulindac to inhibit cell cycle progression in colorectal cancer
Publication date: Available online 16 November 2020Source: Genes & DiseasesAuthor(s): Hongyou Zhao, Bin Yi, Zhipin Liang, Ches’Nique Phillips, Hui-Yi Lin, Adam I. Riker, Yaguang Xi (Source: Genes and Diseases)
Source: Genes and Diseases - November 17, 2020 Category: Genetics & Stem Cells Source Type: research

Bone Morphogenetic Protein 4 (BMP4) promotes hepatic glycogen accumulation and reduces glucose level in hepatocytes through mTORC2 signaling pathway
Publication date: Available online 13 November 2020Source: Genes & DiseasesAuthor(s): Liqin An, Qiong Shi, Ying Zhu, Hao Wang, Qi Peng, Jinghong Wu, Yu Cheng, Wei Zhang, Yanyu Yi, Zihao Bao, Hui Zhang, Yetao Luo, Jiaming Fan (Source: Genes and Diseases)
Source: Genes and Diseases - November 13, 2020 Category: Genetics & Stem Cells Source Type: research

Liver-Specific Mettl3 Ablation Delays Liver Regeneration in Mice
Publication date: Available online 13 November 2020Source: Genes & DiseasesAuthor(s): Jiaxiang Meng, Zhicong Zhao, Zhifeng Xi, Qiang Xia (Source: Genes and Diseases)
Source: Genes and Diseases - November 13, 2020 Category: Genetics & Stem Cells Source Type: research

Pathogenesis of Premature Coronary Artery Disease: Focus on Risk Factors and Genetic Variants
Publication date: Available online 10 November 2020Source: Genes & DiseasesAuthor(s): Haiming Wang, Zifan Liu, Junjie Shao, Min Jiang, Xuechun Lu, Lejian Lin, Lin Wang, Qiang Xu, Haomin Zhang, Xin Li, Jingjing Zhou, Yundai Chen, Ran Zhang (Source: Genes and Diseases)
Source: Genes and Diseases - November 10, 2020 Category: Genetics & Stem Cells Source Type: research

Transient expression of inactive RB in mesenchymal stem cells impairs their adipogenic potential and is associated with hypermethylation of the PPARγ2 promoter
Publication date: Available online 7 November 2020Source: Genes & DiseasesAuthor(s): Mikhail Baryshev, Nikolai Petrov, Vladimir Ryabov, Boris Popov (Source: Genes and Diseases)
Source: Genes and Diseases - November 8, 2020 Category: Genetics & Stem Cells Source Type: research

Characteristics and regulation of mesenchymal stem cell plasticity by the microenvironment —Specific factors involved in the regulation of MSC plasticity
Publication date: Available online 27 October 2020Source: Genes & DiseasesAuthor(s): Liping Tan, Xuan Liu, Huan Dou, Yayi Hou (Source: Genes and Diseases)
Source: Genes and Diseases - October 28, 2020 Category: Genetics & Stem Cells Source Type: research

MicroRNA-9 as a paradoxical but critical regulator of cancer metastasis: Implications in personalized medicine
Publication date: Available online 23 October 2020Source: Genes & DiseasesAuthor(s): Yichen Liu, Qiong Zhao, Tao Xi, Lufeng Zheng, Xiaoman Li (Source: Genes and Diseases)
Source: Genes and Diseases - October 23, 2020 Category: Genetics & Stem Cells Source Type: research