α-Glucosidase inhibitor produced by an endophytic fungus, Xylariaceae sp. QGS 01 from Quercus gilva Blume
Publication date: Available online 10 May 2017 Source:Food Science and Human Wellness Author(s): Anastasia Wheni Indrianingsih, Sanro Tachibana Xylariaceae sp. QGS 01, an endophytic fungus isolated from the stem of Quercus gilva Blume showed high α-glucosidase inhibitory activity. α-Glucosidase inhibitor have the role as one of carbohydrate-hydrolyzing enzymes to postpone absorption of glucose in the digestive organs. The α-glucosidase inhibitor constituents were isolated from the ethyl acetate extract of the mycellium of endophytic fungi Xylariaceae sp. QGS 01 using a bioassay-guided fractionation technique. Furthe...
Source: Food Science and Human Wellness - May 11, 2017 Category: Food Science Source Type: research
Potential antioxidant and cytoprotective effects of essential oil extracted from Cymbopogon citratus on OxLDL and H2O2 LDL induced Human Peripheral Blood Mononuclear Cells (PBMC)
This study has been designed to explore the protective effect of C. citratus (lemon grass) against modified LDL (OxLDL and H2O2 LDL) induced cytotoxicity in Peripheral Blood Mononuclear Cells (PBMC). The essential oil extracted from C. citratus (EOC) was subjected to FT-IR spectroscopic analysis for the identification of functional groups. In vitro antioxidant assays were carried out to assess the electron donating capability of EOC as compared with a known standard L-ascorbic acid. The cytoprotective effects of EOC were determined in PBMC induced with modified LDL. Spectra obtained from FT-IR analysis showed the presence ...
Source: Food Science and Human Wellness - May 8, 2017 Category: Food Science Source Type: research
Dietary fenugreek (Trigonella foenum-graecum) seeds and garlic (Allium sativum) alleviates oxidative stress in experimental myocardial infarction
Publication date: Available online 24 April 2017 Source:Food Science and Human Wellness Author(s): P. Mukthamba, K. Srinivasan Soluble fibre-rich fenugreek seeds (Trigonella foenum- graecum) and garlic (Allium sativum) are understood to exert cholesterol-lowering and antioxidant effects. The cardioprotective influence of a combination of fenugreek seeds and garlic by their antioxidant influence was evaluated in hypercholesterolemic rats administered isoproterenol. Wistar rats were maintained on high-cholesterol diet for 8 weeks along with dietary interventions of fenugreek (10%), garlic (2%) and their combination. Myoc...
Source: Food Science and Human Wellness - April 24, 2017 Category: Food Science Source Type: research
PCR-based Methodologies for Detection and Characterization of Listeria monocytogenes and Listeria ivanovii in Foods and Environmental Sources
Publication date: Available online 2 April 2017 Source:Food Science and Human Wellness Author(s): Jin-Qiang Chen, Stephanie Healey, Patrick Regan, Pongpan Laksanalamai, Zonglin Hu Listeria monocytogenes is an important foodborne pathogen responsible for listeriosis, a fatal disease. It is widely distributed in various foods and environmental sources. In this review, we focused on addressing PCR-based technologies, including conventional PCR, qPCR and droplet digital PCR (ddPCR). Specifically, we described (a) conventional PCR and mono-, duplex- and multiplex-qPCR methodologies; (b) development and applications of ge...
Source: Food Science and Human Wellness - April 2, 2017 Category: Food Science Source Type: research
Toxicological studies of Caesalpinia sappan wood derived dye in Wister albino rats
Publication date: Available online 23 December 2016 Source:Food Science and Human Wellness Author(s): Athinarayanana G., Ranjitsingh A.J.A., Usha Raja Nanthini A., C. Padmalatha Natural dyes taken from the barks of the tree Caesalpinia sappan has been used in many consumer products. Hence it is imperative to test the toxicity of this dye. In the present study an investigation was conducted to find out the toxic effect of aqueous extract of the dye C. sappan in test animal Wister albino rats. Acute oral toxicity showed no clinical signs of toxicity and no mortality even at a dose level of 100–2000mg/kg in 14days obs...
Source: Food Science and Human Wellness - March 26, 2017 Category: Food Science Source Type: research
Phenolic Extract from Ocimum basilicum Restores Lipid Metabolism in Triton WR-1339-induced Hyperlipidemic Mice and Prevents Lipoprotein-rich plasma Oxidation
In this study we investigated the hypolipidemic and anti-lipoprotein-oxidation activities of phenolic extract from sweet basil a popular culinary herb. The hypolipidemic activity was studied in mice model injected intraperitoneally with Triton WR-1339 at a dose of 200mg/kg body weight. The animals were grouped as follows: normolipidemic control group (n=8), hyperlipidemic control group (n=8) and phenolic extract-treated group (n=8) at a dose of 200mg/kg body weight. After 7h and 24h treatment, the oral administration of the phenolic extract exerts a significant reduction of plasma total cholesterol, triglycerides and LDL-c...
Source: Food Science and Human Wellness - March 4, 2017 Category: Food Science Source Type: research
Potential antioxidant and cytoprotective effects of essential oil extracted from Cymbopogan citratus on OxLDL and H2O2 LDL induced Human Peripheral Blood Mononuclear Cells (PBMC)
This study has been designed to explore the protective effect of Cymbopogon citratus (lemon grass) against modified LDL (OxLDL and H2O2 LDL) induced cytotoxicity in Peripheral blood mononuclear cells (PBMC). The essential oil extracted from Cymbopogon citratus (EOC) was subjected to FT-IR spectroscopic analysis for the identification of functional groups. In vitro antioxidant assays were carried out to assess the electron donating capability of EOC as compared with a known standard L-ascorbic acid. The cytoprotective effects of EOC were determined in PBMC induced with modified LDL. Spectra obtained from FT-IR analysis show...
Source: Food Science and Human Wellness - February 23, 2017 Category: Food Science Source Type: research
Toxicological studies of caesalpinia sappanwood derived dye in wister albino rats
Publication date: Available online 23 December 2016 Source:Food Science and Human Wellness Author(s): G. Athinarayanana, A.J.A. Ranjitsingh, A. Usha Raja Nanthini, C. Padmalatha Natural dyes taken from the barks of the tree Caesalpinia sappanhas been used in many consumer products. Hence it is imperative to test the toxicity of this dye. In the present study an investigation was conducted to find out the toxic effect of aqueous extract of the dye C.sappanin test animal wister albino rats. Acute oral toxicity showed no clinical signs of toxicity and no mortality even at a dose level of 100–2000mg/kg in 14days observ...
Source: Food Science and Human Wellness - December 22, 2016 Category: Food Science Source Type: research
Reversal of acetaminophen-generated oxidative stress and concomitant hepatotoxicity by a phytopharmaceutical product
In this study, Trévo™, a nutraceutical and phytopharmaceutical product, was evaluated for beneficial effects in acetaminophen-induced hepatic toxicity in Wistar rats. Animals received Trévo™ (1.5ml/kg, 3.0ml/kg or 4.5ml/kg) orally for 14 days. Hepatotoxicity was induced by the oral administration of acetaminophen (2g/kg), 24h prior to sacrifice. Biochemical liver function tests, oxidative stress indicators and histoarchitectural changes were evaluated. Acetaminophen administration occasioned significant increase (P<0.05) in serum bilirubin level and activities of the aminotransferases, alkaline phosphatase, γ...
Source: Food Science and Human Wellness - December 6, 2016 Category: Food Science Source Type: research
Quantification of phenolic compounds and antioxidant capacity of an underutilized Indian fruit: Rayan [Manilkara hexandra (Roxb.) Dubard]
Publication date: Available online 6 December 2016 Source:Food Science and Human Wellness Author(s): Bhumi Parikh, V.H. Patel The fruit of Manilkara hexandra (Roxb.) Dubard is one of the most underutilized fruits of India and in Gujarat state it is popularly known as ‘Rayan’. The fruit and seed of Rayan were analysed for their total phenolic and flavonoid content, phenolic compounds and total antioxidant capacity with six different assay methods. The results of these analyses indicated that the methanolic extract of Rayan fruit proved to be a good source of phenolic (811.3mg GAE/100g fw) and flavonoid (485.56mg RE/...
Source: Food Science and Human Wellness - December 6, 2016 Category: Food Science Source Type: research
Reducing oxidative stress and hepatoprotective effect of water extracts from Pu-erh tea on rats with high-fat diet
Publication date: Available online 18 October 2016 Source:Food Science and Human Wellness Author(s): Jing Jing Su, Xue Qing Wang, Wen Jun Song, Xiao Li Bai, Chang Wen Li Reducing oxidative stress and hepatoprotective effect of Pu-erh tea water extracts on rats fed with high-fat diet were researched for explaining health care of Pu-erh tea. Fifty SD rats were divided into five groups. The body weight was measured once a day. The malondialdehyde (MDA) and glucose (Glu) levels and the activities of alanine aminotransferase (ALT), aspartate aminotransferase (AST), nitric oxide synthase (NOS), and pyruvate kinase (PK) in...
Source: Food Science and Human Wellness - November 30, 2016 Category: Food Science Source Type: research
Ketogenic diets and Alzheimer ’s disease
Publication date: Available online 24 November 2016 Source:Food Science and Human Wellness Author(s): Klaus W. Lange, Katharina M. Lange, Ewelina Makulska-Gertruda, Yukiko Nakamura, Andreas Reissmann, Shigehiko Kanaya, Joachim Hauser Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by decline in cognitive functions and associated with the neuropathological hallmarks of amyloid β-peptide plaques and neurofibrillary tangles. Cerebral glucose uptake and metabolism deteriorate in AD and this hypometabolism precedes the onset of clinical signs in AD. The early decline in brain gluco...
Source: Food Science and Human Wellness - November 24, 2016 Category: Food Science Source Type: research
Thermo-mechanical and Micro-structural Properties of Xylanase Containing Whole Wheat Bread
In this study, influence of xylanase on the physicochemical properties and sensory qualities of the whole wheat bread during storage was investigated. Microstructure, textural, thermal, Scanning Electron Microscopic (SEM), X-Ray Diffraction (XRD) studies of whole wheat bread were conducted at ambient temperature of 25 and 4°C. During storage at different temperatures, bread containing xylanase exhibited less firmness but larger volume with whiter crumb color and longer shelf life as compared to control bread. Results of firmness, enthalpy, Fourier Transformation Infra Red (FTIR) and X-Ray Diffraction (XRD) studies suggest...
Source: Food Science and Human Wellness - October 26, 2016 Category: Food Science Source Type: research
Biological activities of silver nanoparticles from Nothapodytes nimmoniana (Graham) Mabb. Fruit extracts.
Publication date: Available online 17 October 2016 Source:Food Science and Human Wellness Author(s): G. Mahendran, B.D.Ranjitha Kumari In the present investigation, we have described the green biosynthesis of silver nanoparticles (AgNPs) using ripened fruit aqueous extract of Nothapodytes nimmoniana (Graham) Mabb. as capping agent and its antioxidant, anticancer and antimicrobial activities. UV analysis revealed that AgNPs had a sharp peak at 416nm. X-ray Diffraction (XRD) result confirmed the characteristic peaks indicated at 111, 200, 220 and 311 for the crystalline of the face centered cubic silver. The Scanning Ele...
Source: Food Science and Human Wellness - October 24, 2016 Category: Food Science Source Type: research
Reducing oxidative stress and hepatoprotective effect of the water extracts from Pu-erh tea on rats fed with high-fat diet
Publication date: Available online 18 October 2016 Source:Food Science and Human Wellness Author(s): Jing Jing Su, Xue Qing Wang, Wen Jun Song, Xiao Li Bai, Chang Wen Li Reducing oxidative stress and hepatoprotective effect of Pu-erh tea water extracts on rats fed with high-fat diet were researched for explaining health care of Pu-erh tea. Fifty SD rats were divided into five groups. The body weight was measured once a day. The malondialdehyde (MDA) and glucose (Glu) levels and the activities of alanine aminotransferase (ALT), aspartate aminotransferase (AST), nitric oxide synthase (NOS), and pyruvate kinase (PK) in...
Source: Food Science and Human Wellness - October 24, 2016 Category: Food Science Source Type: research
