Effects of Periconception Cadmium and Mercury Co-Administration to Mice on Indices of Chronic Disease in Male Offspring at Maturity
Conclusions: Results suggest administration of cadmium and mercury to female mice during early development of their offspring (which in this study is the periconception period) was associated with anxiety-like behavior, altered glucose metabolism and insulin resistance in male offspring at adulthood. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is ava...
Source: EHP Research - November 4, 2016 Category: Environmental Health Authors: Web Admin Tags: Research Articles Source Type: research

Serum Metabolomic Profiles in Neonatal Mice following Oral Brominated Flame Retardant Exposures to Hexabromocyclododecane (HBCD) Alpha, Gamma, and Commercial Mixture
Conclusions: We demonstrate that four days following a single neonatal oral exposure to α-, γ-, and CM-HBCD results in different serum metabolomic profiles, indicating stereoisomer- and mixture-specific effects and possible mechanisms of action. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you wil...
Source: EHP Research - November 4, 2016 Category: Environmental Health Authors: Web Admin Tags: Research Articles Source Type: research

Combined Effects of in Utero and Adolescent Tobacco Smoke Exposure on Lung Function in C57Bl/6J Mice
Conclusions: Our findings suggest that prenatal and adolescent CS exposure have a synergistic effect on lung function in mice. The combined effect did not appear to be a consequence of early pulmonary senescence. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this docume...
Source: EHP Research - November 4, 2016 Category: Environmental Health Authors: Web Admin Tags: Research Articles Source Type: research

After the Research Is Done: Legal Obligations for Participants in Household Exposure Studies
Julia R. Barrett, MS, ELS, a Madison, WI–based science writer and editor, is a member of the National Association of Science Writers and the Board of Editors in the Life Sciences. About This Article open Citation: Barrett JR. 2016. After the research is done: legal obligations for participants in household exposure studies. Environ Health Perspect 124:A206; http://dx.doi.org/10.1289/124-A206 Published: 1 November 2016 PDF Version (438 KB) Related EHP Article The Legal Implications of Report Back in Household Exposure Studies Shaun A. Goho Household chemical exposure studies are essential for assessing hu...
Source: EHP Research - November 1, 2016 Category: Environmental Health Authors: Web Admin Tags: News Science Selections November 2016 Source Type: research

Montreal ’s Strategy for Hot Days: Evaluating the Effectiveness of One City’s Heat Action Plan
Nate Seltenrich covers science and the environment from Petaluma, CA. His work has appeared in High Country News, Sierra, Yale Environment 360, Earth Island Journal, and other regional and national publications. About This Article open Citation: Seltenrich N. 2016. Montreal’s strategy for hot days: evaluating the effectiveness of one city’s heat action plan. Environ Health Perspect 124:A207; http://dx.doi.org/10.1289/124-A207 Published: 1 November 2016 PDF Version (600 KB) Related EHP Article A Difference-in-Differences Approach to Assess the Effect of a Heat Action Plan on Heat-Related Mortality, and Diffe...
Source: EHP Research - November 1, 2016 Category: Environmental Health Authors: Web Admin Tags: News Science Selections November 2016 Source Type: research

Pacific Island Countries and Climate Change: Examining Associated Human Health Vulnerabilities
Nancy Averett writes about science and the environment from Cincinnati, OH. Her work has been published in Pacific Standard, Audubon, Discover, E/The Environmental Magazine, and a variety of other publications. About This Article open Citation: Averett N. 2016. Pacific island countries and climate change: examining associated human health vulnerabilities. Environ Health Perspect 124:A208; http://dx.doi.org/10.1289/124-A208 Published: 1 November 2016 PDF Version (645 KB) Related EHP Article Health Impacts of Climate Change in Pacific Island Countries: A Regional Assessment of Vulnerabilities and Adaptation Prior...
Source: EHP Research - November 1, 2016 Category: Environmental Health Authors: Web Admin Tags: News Science Selections November 2016 Source Type: research

Institutes in the Lead: Identifying Environmental Factors in Breast Cancer
Since the early 1990s the National Institute of Environmental Health Sciences and the National Cancer Institute have conducted and funded countless studies on potential environmental risk factors for breast cancer. While clear answers are still hard to come by in this highly complex field, increasingly sophisticated research questions and methods have yielded intriguing evidence.© Agence Photographique BSIP/Getty Images A suspected cluster of breast cancer cases on Long Island launched what has become a robust body of evidence on environmental risk factors for breast cancer. The hatching on this map in...
Source: EHP Research - November 1, 2016 Category: Environmental Health Authors: Web Admin Tags: News Focus November 2016 Source Type: research

Erratum: “Zika in the United States: How Are We Preparing?”
About This Article open Citation: Schmidt CW. 2016. Erratum: “Zika in the United States: How Are We Preparing?” Environ Health Perspect 124:A198; http://dx.doi.org/10.1289/EHP1096 Final Publication: 1 November 2016   PDF Version (54 KB) Related EHP Article Zika in the United States: How Are We Preparing? Charles W. Schmidt Environ Health Perspect 124(9):A157–A165 (2016), http://dx.doi.org/10.1289/ehp.124-A157 In the following sentence, the 147 cases of microcephaly reported in Brazil in 2014 were incorrectly characterized as being about 10 times higher than the average baseline rate seen in other countr...
Source: EHP Research - November 1, 2016 Category: Environmental Health Authors: Web Admin Tags: Perspectives Erratum November 2016 Source Type: research

Commemorating Toxicology at the National Institute of Environmental Health Sciences on the Occasion of Its 50th Anniversary
Author Affiliations open 1Division of the National Toxicology Program (NTP), and 2National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina USA PDF Version (3 MB) Summary About This Article In 1978, the National Toxicology Program (NTP) was established and headquartered at the National Institute of Environmental Health Sciences (NIEHS) in Research Triangle Park, North Carolina. On the occasion of the 50th Anniversary of the NIEHS, this article documents some of the historical and current NTP p...
Source: EHP Research - November 1, 2016 Category: Environmental Health Authors: Web Admin Tags: Perspectives Brief Communication November 2016 Source Type: research

Comment on “Rheumatoid Arthritis in Agricultural Health Study Spouses: Associations with Pesticides and Other Farm Exposures”
1Rheumatology Department, Royal Cornwall Hospital, Truro, Cornwall, United Kingdom; 2University of Exeter Medical School, Truro, Cornwall, United Kingdom About This Article open Citation: Murphy D, Pay J, Benham R, James B, Hutchinson D. 2016. Comment on “Rheumatoid Arthritis in Agricultural Health Study Spouses: Associations with Pesticides and Other Farm Exposures.” Environ Health Perspect 124:A196; http://dx.doi.org/10.1289/EHP730 Address correspondence to D. Murphy, Rheumatology Department, Royal Cornwall Hospital, Truro, Cornwall, TR1 3LJ United Kingdom. E-mail: daniel.murphy8@nhs.net Support for the autho...
Source: EHP Research - November 1, 2016 Category: Environmental Health Authors: Web Admin Tags: Perspectives Correspondence November 2016 Source Type: research

Response to “Comment on ‘Rheumatoid Arthritis in Agricultural Health Study Spouses: Associations with Pesticides and Other Farm Exposures’”
1Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA; 2Center for Human Health and the Environment, Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, USA; 3Department of Environmental and Occupational Health, Drexel University School of Public Health, Philadelphia, Pennsylvania, USA; 4Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA. About This Article open Citation: Parks CG, Hoppin JA, De Roos AJ...
Source: EHP Research - November 1, 2016 Category: Environmental Health Authors: Web Admin Tags: Perspectives Correspondence November 2016 Source Type: research

The Legal Implications of Report Back in Household Exposure Studies
Conclusions: Researchers should still report back to participants who want to see their results, but they should disclose the risks of obtaining the information as part of the informed consent process. Citation: Goho SA. 2016. The legal implications of report back in household exposure studies. Environ Health Perspect 124:1662–1670; http://dx.doi.org/10.1289/EHP187 Address correspondence to S.A. Goho, Suite 4119, 6 Everett St., Cambridge, MA 02138 USA. Telephone: (617) 496-5692. E-mail: sgoho@law.harvard.edu This research derives from an idea developed by J. Brody and R. Rudel. P. Brown, J. Brody, R. Rudel, and W. Jaco...
Source: EHP Research - November 1, 2016 Category: Environmental Health Authors: Web Admin Tags: Reviews November 2016 Source Type: research

Advancing Alternative Analysis: Integration of Decision Science
Conclusions: We advance four recommendations: (1) engaging the systematic development and evaluation of decision approaches and tools; (2) using case studies to advance the integration of decision analysis into alternatives analysis; (3) supporting transdisciplinary research; and (4) supporting education and outreach efforts. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted ve...
Source: EHP Research - October 28, 2016 Category: Environmental Health Authors: Web Admin Tags: Review Source Type: research

The Prevalence of Antibiotic-Resistant Staphylococcus aureus Nasal Carriage among Industrial Hog Operation Workers, Community Residents, and Children Living in Their Households: North Carolina, USA
Conclusion: Our findings support the importance of further research on the prevalence and potential sources of exposure to ABR S. aureus among children living with IHO workers. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the publication proces...
Source: EHP Research - October 18, 2016 Category: Environmental Health Authors: Web Admin Tags: Research Article Children's Health Source Type: research

Sex-Specific Associations between Particulate Matter Exposure and Gene Expression in Independent Discovery and Validation Cohorts of Middle-Aged Men and Women
Conclusions: Expression of the sex-specific candidate genes identified in the discovery population predicted PM10 exposure in an independent cohort of adults from the same area. Confirmation in other populations may further support this as a new approach for exposure assessment, and may contribute to the discovery of molecular mechanisms for PM-induced health effects. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replac...
Source: EHP Research - October 14, 2016 Category: Environmental Health Authors: Web Admin Tags: Research Article Source Type: research