A 10 year retrospective review of fine needle aspiration cytology of cystic lesions of the breast with emphasis on papillary cystic lesions
ConclusionsFNA allows accurate diagnosis of benign cystic lesions. FNA also plays a prominent role in evaluating cystic papillary lesions of the breast and helps to prevent false negative results on the simultaneous CNB. It is essential that FNA and CNB diagnoses be used in combination to make the correct diagnosis and for clinical management. (Source: Diagnostic Cytopathology)
Source: Diagnostic Cytopathology - November 23, 2018 Category: Pathology Authors: Xin He, Yihong Wang, Gahie Nam, Ana P Lourenco, Latha Pisharodi Tags: ORIGINAL ARTICLE Source Type: research

Cell block cellularity: A comparison of two fixatives and their impact on cellularity
ConclusionsCell blocks prepared using a formalin fixative yield significantly greater cellularity than those produced by the CytoLyt method. Formalin fixation appears to optimize cellularity of cell blocks useful for ancillary testing. (Source: Diagnostic Cytopathology)
Source: Diagnostic Cytopathology - November 23, 2018 Category: Pathology Authors: Lester J. Layfield, Magda Esebua, Jonathan Ang, Mohammed M. Alnijoumi, Harijyot S. Sohal, Richard D. Hammer, Nitya Prabhakaran, Robert L. Schmidt Tags: ORIGINAL ARTICLE Source Type: research

Mediastinal seminoma presenting as a neck mass falsely diagnosed as anaplastic thyroid carcinoma: A case report
Germ cell tumors can occur in the mediastinum. They account for about 20% of tumors at this location. The majority are located in the anterior mediastinum and usually occur in young adult males. Extension of mediastinal germ cell tumors into the neck with mass formation is a very rare and unusual event. Herein, we report a case of a 34 year old male who presented with a progressively enlarging neck mass. Fine Needle Aspiration (FNA) was performed as initial evaluation and showed cellular smears comprising atypical large cells with prominent irregular nucleoli and moderate amount of cytoplasm with lymphocytic infiltrate and...
Source: Diagnostic Cytopathology - November 23, 2018 Category: Pathology Authors: Khaled Murshed, Issam Al ‐Bozom, Surjith Vattoth, Mohammed Akhtar Tags: BRIEF REPORT Source Type: research

Cytomorphological features of high ‐grade intraepithelial neoplasia/carcinoma of the cervix following chemoradiotherapy
ConclusionsIn patients with CRT, the presence of specific features can help the diagnosis of H ‐SIL with excellent diagnostic performance. (Source: Diagnostic Cytopathology)
Source: Diagnostic Cytopathology - November 23, 2018 Category: Pathology Authors: M ónica L. Serrano‐Arévalo, Lorena Flores‐Hernández, Lidia F. Villegas‐González, Sandy Zamora‐Zarco, Alejandro España‐Ferrufino, Leonardo S. Lino‐Silva, Salim A. Barquet‐Muñoz Tags: ORIGINAL ARTICLE Source Type: research

Role of fine needle aspiration cytology in the management of supraclavicular lymph node metastasis: Review of our experience
ConclusionsThe origin of SLN metastasis seems to be dependent on both the frequency of tumor types in each geographic area and tumor location. Left SLN are more frequently involved by infradiaphragmatic primary tumors, while right SLN are exclusively involved by supradiaphragmatic neoplasms. (Source: Diagnostic Cytopathology)
Source: Diagnostic Cytopathology - November 23, 2018 Category: Pathology Authors: M ª Jesús Fernández Aceñero, Ana Caso Viesca, Cristina Díaz del Arco Tags: ORIGINAL ARTICLE Source Type: research

Spindle cell lipoma mimicking pleomorphic adenoma: A diagnostic challenge on cytology
We present a case of a 36 ‐year‐old female with a swelling in the left preauricular region since last 6 mo. On fine needle aspiration, a diagnosis of lipomatous pleomorphic adenoma (PA) was rendered because of the presence of benign spindle‐shaped cells, adipocytes, and abundant myxoid material. However, on histopathol ogic examination, the diagnosis was SCL which was confirmed by immunohistochemistry. Preauricular region is a rare site of occurrence of SCL. An acquaintance with its varied cytomorphologic features and a knowledge of its unusual sites of occurrence is essential to prevent its misdiagnosis as other myx...
Source: Diagnostic Cytopathology - November 23, 2018 Category: Pathology Authors: Manveen Kaur, Debajyoti Chatterjee, Reetu Kundu, Rajpal S. Punia, Vaibhav Saini Tags: BRIEF REPORT Source Type: research

Glioblastoma with primitive neuronal component: Cytologic findings in intraoperative squash preparations
Diagnostic Cytopathology, EarlyView. (Source: Diagnostic Cytopathology)
Source: Diagnostic Cytopathology - November 23, 2018 Category: Pathology Authors: Ewa Borys, Vikram C. Prabhu, Stefan E. Pambuccian Tags: IMAGES IN CYTOLOGY Source Type: research

The utility of combined mutation analysis and microRNA classification in reclassifying cancer risk of cytologically indeterminate thyroid nodules
ConclusionsMutation panels alone do not sufficiently risk stratify thyroid nodular disease. microRNA classification complements cytology and mutation analysis with the capacity to better differentiate nodules at high risk of malignancy. (Source: Diagnostic Cytopathology)
Source: Diagnostic Cytopathology - November 22, 2018 Category: Pathology Authors: Anna B. Banizs, Jan F. Silverman Tags: ORIGINAL ARTICLE Source Type: research

Galactocele of adult male breast: A cytopathologist's perspective
Galactocele, although a common cytological diagnosis in females, is not previously reported as a cause of breast enlargement in adult males. Hyperprolactinemia is the principal cause of galactocele in male breast. Besides drug induced hyperprolactinemia, other anatomical lesions of hypothalamo ‐pituitary region and different medical conditions like cirrhosis and chronic kidney disease are to be considered along with a full evaluation of features revealing hypogonadism in case of galactocele. Aspirated milk from the male breast is the primary clue for this detailed investigation process. Here we are presenting the first c...
Source: Diagnostic Cytopathology - November 21, 2018 Category: Pathology Authors: Arghya Bandyopadhyay, Kaushik Sen, Nirmalya Chakrabarti, Shantanu Datta Tags: BRIEF REPORT Source Type: research

Smear cytological features of large cell neuroendocrine carcinoma of the uterine cervix in pregnancy: A case report and review of the literature
Large ‐cell neuroendocrine carcinoma (LCNEC) of the uterine cervix is a rare aggressive tumor. The examination of a cervicovaginal smear from a 31‐year‐old patient diagnosed with LCNEC after a cervical polypectomy during the 32nd week of pregnancy was carried out. The observed atypical cells had lar ge cytoplasm, increased nucleus: cytoplasm ratio with the nucleus containing coarse, dispersed chromatin, and were arranged in a pseudorosette formation, which all confirmed the diagnosis. In addition, adenocarcinoma in situ (AIS) was determined in the histopathological examination of the subsequent hysterectomy material....
Source: Diagnostic Cytopathology - November 21, 2018 Category: Pathology Authors: Busra Ersan Erdem, Vural Çiğdem, Gezer Şener, Muezzinoglu Bahar, Yıldız Demir Kursat, Yucesoy İzzet Tags: BRIEF REPORT Source Type: research

The diagnostic value of parathyroid hormone washout in primary hyperparathyroidism patients with negative or equivocal 99 m Tc ‐MIBI results
ConclusionsFNA ‐PTH can be used to establish the nature of the lesion, discriminate parathyroid gland from thyroid lesions or cervical lymph nodes, improving the surgical outcomes. It can be used to localise parathyroid lesions preoperatively when negative or discordant ultrasound and scintigraphy findings are o btained. (Source: Diagnostic Cytopathology)
Source: Diagnostic Cytopathology - November 21, 2018 Category: Pathology Authors: Cevdet Ayd ın, Sefika Burcak Polat, Fatma Dilek Dellal, Cafer Kaya, Hayriye Tatlı Dogan, Seyda Turkolmez, Mehmet Kılıç, Reyhan Ersoy, Bekir Çakır Tags: ORIGINAL ARTICLE Source Type: research

Fine ‐needle aspiration of alveolar soft part sarcoma: Histologic correlation and aberrant CD68 expression
We report two cases of alveolar soft part sarcoma: a 24 ‐year‐old Latino man with a 10‐cm neck mass and a 56 ‐year‐old Latino woman with a recurring thigh mass. Fine‐needle aspiration and a core biopsy were performed on both, which was followed by tumor resection on the man. The smears displayed numerous loosely cohesive or single large cells with abundant granular cytoplasm, round nuclei, vesicular chromatin, and occasional prominent nucleoli. Periodic and Schiff (PAS)‐positive, diastase‐resistant rhomboid, or needle‐shaped crystals were present. Both tumors had diffuse and strong nuclear TFE3 expression...
Source: Diagnostic Cytopathology - November 20, 2018 Category: Pathology Authors: Ya Xu, Ting Zhou, Wendong Yu, Neda Zarrin ‐Khameh Tags: BRIEF REPORT Source Type: research

Vermi ‐trouble: Cytology of an arm swelling
Diagnostic Cytopathology, EarlyView. (Source: Diagnostic Cytopathology)
Source: Diagnostic Cytopathology - November 20, 2018 Category: Pathology Authors: Parikshaa Gupta, Nalini Gupta, Arvind Rajwanshi Tags: IMAGES IN CYTOLOGY Source Type: research

Advantage of Z ‐stacking for teleconsultation between the USA and Colombia
ConclusionThis study demonstrated that international telecytology for diagnostic purposes is feasible. Panoramic images had to be acquired manually, but were of suitable diagnostic quality and generated smaller image files associated with fewer technical errors. Z ‐stacking proved to be useful in the majority of cases and is thus recommended for telecytology. (Source: Diagnostic Cytopathology)
Source: Diagnostic Cytopathology - November 20, 2018 Category: Pathology Authors: Andres Mosquera ‐Zamudio, Matthew G. Hanna, Rafael Parra‐Medina, Ana C. Piedrahita, Paula A. Rodriguez‐Urrego, Liron Pantanowitz Tags: SPECIAL ISSUE ARTICLE Source Type: research

Prevalence of high ‐risk human papilloma virus in liquid‐based cervical samples from Turkish women with normal and abnormal cytology
ConclusionsThe HPV prevalence among Turkish women with normal and abnormal cytology identified in this study largely concurs with those in other studies throughout the world. HPV types 16 and/or 18 were detected significantly in normal cytology cases in our study. We also found that, as has been previously demonstrated, certain HPV genotypes (16/18) are associated with more severe pathologies. However, larger epidemiological studies in different regions of Turkey are needed to evaluate the accurate prevalence of HPV infection throughout the country. (Source: Diagnostic Cytopathology)
Source: Diagnostic Cytopathology - November 20, 2018 Category: Pathology Authors: Hatice Seneldir, Gozde Kir Tags: ORIGINAL ARTICLE Source Type: research