Negative-pressure wound therapy for management of diabetic foot wounds: a review of the mechanism of action, clinical applications, and recent developments.
Authors: Hasan MY, Teo R, Nather A
Abstract
Negative-pressure wound therapy (NPWT) plays an important role in the treatment of complex wounds. Its effect on limb salvage in the management of the diabetic foot is well described in the literature. However, a successful outcome in this subgroup of diabetic patients requires a multidisciplinary approach with careful patient selection, appropriate surgical debridement, targeted antibiotic therapy, and optimization of healing markers. Evolving NPWT technology including instillation therapy, nanocrystalline adjuncts, and portable systems can further improve resul...
Source: Diabetic Foot and Ankle - December 20, 2015 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research
Retrograde pedal access with a 20-gauge intravenous cannula after failed antegrade recanalization of a tibialis anterior artery in a diabetic patient: a case report.
We report a retrograde puncturing technique in patients with chronic total occlusions. After failed antegrade recanalization, puncturing and cannulation of a tiny dorsalis pedis artery with a narrow bore [20-gauge (0.8 mm)] intravenous cannula is described.
PMID: 26257023 [PubMed] (Source: Diabetic Foot and Ankle)
Source: Diabetic Foot and Ankle - December 20, 2015 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research
Intralesional epidermal growth factor for diabetic foot wounds: the first cases in Turkey.
CONCLUSION: Thus, this preliminary study suggests that EGF seems to be a potential adjunctive treatment option in patients with limb-threatening diabetic foot wounds.
PMID: 26268583 [PubMed] (Source: Diabetic Foot and Ankle)
Source: Diabetic Foot and Ankle - December 20, 2015 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research
Risk factors for lower extremity amputation in patients with diabetic foot ulcers: a hospital-based case-control study.
CONCLUSIONS: Several risk factors for LEA were identified. We found that HbA1c ≥8%, PAD, hypertriglyceridemia, and hypertension have been recognized as the predictors of LEA in this study. Good glycemic control, active investigation against PAD, and management of comorbidities such as hypertriglyceridemia and hypertension are considered important to reduce amputation risk.
PMID: 26651032 [PubMed - as supplied by publisher] (Source: Diabetic Foot and Ankle)
Source: Diabetic Foot and Ankle - December 20, 2015 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research
