The modified Pirogoff's amputation in treating diabetic foot infections: surgical technique and case series.
CONCLUSIONS: The modified Pirogoff's amputation has been found to show good results in carefully selected patients with diabetic foot infections. The selection criteria included a palpable posterior tibial pulse, distal infections not extending proximally beyond the midfoot level, ABI of more than 0.7, hemoglobin level of more than 10 g/dL, and serum albumin level of more than 30 g/L. PMID: 24711887 [PubMed] (Source: Diabetic Foot and Ankle)
Source: Diabetic Foot and Ankle - December 20, 2015 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research

A study of prognostic factors in Chinese patients with diabetic foot ulcers.
CONCLUSION: In this retrospective study, we conclude that the DFU prognosis may be related to age, gender, wound location (heel), Wagner wound classification, ABI, and TcPO2 levels in the Chinese population. PMID: 24765244 [PubMed] (Source: Diabetic Foot and Ankle)
Source: Diabetic Foot and Ankle - December 20, 2015 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research

Vacuum-assisted closure versus conventional dressings in the management of diabetic foot ulcers: a prospective case-control study.
CONCLUSION: VAC appears to be more effective, safe, and patient satisfactory compared to conventional dressings for the treatment of DFUs. PMID: 24765245 [PubMed] (Source: Diabetic Foot and Ankle)
Source: Diabetic Foot and Ankle - December 20, 2015 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research

Risk factors for methicillin-resistant Staphylococcus aureus in diabetic foot infections.
CONCLUSION: Positive nasal swabs are not predictive of the infecting agent; however, a negative nasal swab rules out MRSA as the infecting agent in foot wounds with 90% accuracy. PMID: 24765246 [PubMed] (Source: Diabetic Foot and Ankle)
Source: Diabetic Foot and Ankle - December 20, 2015 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research

Complication rates in diabetics with first metatarsophalangeal joint arthrodesis.
CONCLUSION: In conclusion, first MTPJ arthrodesis is overall an effective and beneficial procedure in patients with diabetes mellitus. Diabetic patients with peripheral neuropathy have an increased risk for mild and moderate complications. PMID: 24987496 [PubMed] (Source: Diabetic Foot and Ankle)
Source: Diabetic Foot and Ankle - December 20, 2015 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research

Osteomyelitis in the diabetic foot.
Authors: Malhotra R, Chan CS, Nather A Abstract Osteomyelitis (OM) is a common complication of diabetic foot ulcers and/or diabetic foot infections. This review article discusses the clinical presentation, diagnosis, and treatment of OM in the diabetic foot. Clinical features that point to the possibility of OM include the presence of exposed bone in the depth of a diabetic foot ulcer. Medical imaging studies include plain radiographs, magnetic resonance imaging, and bone scintigraphy. A high index of suspicion is also required to make the diagnosis of OM in the diabetic foot combined with clinical and rad...
Source: Diabetic Foot and Ankle - December 20, 2015 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research

Effect of painless diabetic neuropathy on pressure pain hypersensitivity (hyperalgesia) after acute foot trauma.
CONCLUSION: Physiological nociception and post-traumatic hyperalgesia to pressure are diminished at the foot with severe painless (diabetic) neuropathy. A degree of post-traumatic hypersensitivity required to 'pull away' from any one, even innocuous, mechanical impact in order to avoid additional damage is, therefore, lacking. PMID: 25397867 [PubMed] (Source: Diabetic Foot and Ankle)
Source: Diabetic Foot and Ankle - December 20, 2015 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research

The role of Renasys-GO™ in the treatment of diabetic lower limb ulcers: a case series.
CONCLUSIONS: Renasys-GO™ therapy may be beneficial in the treatment of diabetic lower limb ulcers and wounds. In this study, which included wounds presenting as post-surgery ray amputation, metatarsal excision wounds, post-debridement abscesses and ulcers, the Renasys-GO™ therapy prepared all wounds for closure via split-thickness skin grafting or secondary healing by promoting granulation tissue and reducing bacterial infection in approximately 2 weeks. PMID: 25406680 [PubMed] (Source: Diabetic Foot and Ankle)
Source: Diabetic Foot and Ankle - December 20, 2015 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research

The lateral lesser toe fillet flap for diabetic foot soft tissue closure: surgical technique and case report.
Authors: Chung SR, Wong KL, Cheah AE Abstract Wound closure for the diabetic foot can be challenging and often involves amputation or reconstruction. The authors describe a surgical technique and a case report of lateral lesser toe fillet flap in the management of a diabetic foot wound. The lateral lesser toe fillet flap reconstruction is a reproducible technique that incurs comparatively minimal technical complexity and provides a favorable option in the management of diabetic foot wounds where soft tissue coverage is required. PMID: 25527137 [PubMed] (Source: Diabetic Foot and Ankle)
Source: Diabetic Foot and Ankle - December 20, 2015 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research

Reduction of pain via platelet-rich plasma in split-thickness skin graft donor sites: a series of matched pairs.
Authors: Miller JD, Rankin TM, Hua NT, Ontiveros T, Giovinco NA, Mills JL, Armstrong DG Abstract In the past decade, autologous platelet-rich plasma (PRP) therapy has seen increasingly widespread integration into medical specialties. PRP application is known to accelerate wound epithelialization rates, and may also reduce postoperative wound site pain. Recently, we observed an increase in patient satisfaction following PRP gel (Angel, Cytomedix, Rockville, MD) application to split-thickness skin graft (STSG) donor sites. We assessed all patients known to our university-based hospital service who underwent ...
Source: Diabetic Foot and Ankle - December 20, 2015 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research

Use of collagenase ointment in conjunction with negative pressure wound therapy in the care of diabetic wounds: a case series of six patients.
CONCLUSION: In our experience, we have noticed a specific subgroup of patients who benefit greatly when collagenase enzymatic debridement therapy is combined with NPWT. It is our belief that this combination therapy combines the molecular clearing of non-viable collagen with the wound granulation necessary to advance complex wounds to the next step in healing despite the current paucity in literature discussing this specific pairing. PMID: 25630362 [PubMed] (Source: Diabetic Foot and Ankle)
Source: Diabetic Foot and Ankle - December 20, 2015 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research

Staphylococcus aureus small colony variants in diabetic foot infections.
Conclusions : The antibiotic therapy commonly used in diabetic patients with infected diabetic foot ulcers fails in the case of MRSA-SCVs because the intracellular location protects S. aureus-SCVs from the host's defenses and also helps them resist antibiotics. The cases studied in this article add to the spectrum of persistent and relapsing infections attributed to MRSA-SCVs and emphasizes that these variants may also play a relevant role in diabetic foot infections. PMID: 25787018 [PubMed] (Source: Diabetic Foot and Ankle)
Source: Diabetic Foot and Ankle - December 20, 2015 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research

A literature-based guide to the conservative and surgical management of the acute Charcot foot and ankle.
Authors: Schade VL, Andersen CA Abstract Acute Charcot neuroarthropathy of the foot and ankle presents with the insidious onset of a unilateral acutely edematous, erythematous, and warm lower extremity. The acute stages are typically defined as Eichenholtz Stage 1, or Stage 0, which was first described by Shibata et al. in 1990. The ultimate goal of treatment is maintenance of a stable, plantigrade foot which can be easily shod, minimizing the risk of callus, ulceration, infection, and amputation. The gold standard of treatment is non-weight-bearing immobilization in a total contact cast. Surgical interven...
Source: Diabetic Foot and Ankle - December 20, 2015 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research

A prospective audit of the impact of additional staff on the care of diabetic patients in a community podiatry service.
DISCUSSION: During the life cycle of this audit, increased numbers of patients were treated and waiting times for patients with diabetes were reduced. An internal re-organisation of the services coincided with the commencement of the additional staff. The improvements observed were due to the effects of a combination of additional staff and service re-organisation. Efficient organisation of services is key to optimal performance. Continued efforts to improve services are required to reach the standards outlined in the NICE guidelines. PMID: 26048860 [PubMed] (Source: Diabetic Foot and Ankle)
Source: Diabetic Foot and Ankle - December 20, 2015 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research

Foot deformities, function in the lower extremities, and plantar pressure in patients with diabetes at high risk to develop foot ulcers.
CONCLUSIONS: This study identified several potential risk factors for the onset of diabetic foot ulcers (DFU). Hallux valgus and hallux rigidus appeared to increase the PP under the medial forefoot and a high BMI appeared to increase the PP under the lateral forefoot. There is a need to construct a simple, valid, and reliable assessment routine to detect potential risk factors for the onset of DFU. PMID: 26087865 [PubMed] (Source: Diabetic Foot and Ankle)
Source: Diabetic Foot and Ankle - December 20, 2015 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research