Diabetes/Metabolism Research and Reviews This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Decline in the Acute Insulin Response in Relationship to Plasma Glucose Concentrations
ConclusionsWith worsening insulin action, the decline in insulin secretion occurred prior to current diagnostic guidelines for impaired glucose regulation. However, the relationship between AIR and increasing PG varies, and was not always non‐linear. Understanding the dynamics of this relationship may determine when to initiate preventive pharmacotherapy directed at the preservation of β‐cell failure. (Source: Diabetes/Metabolism Research and Reviews)
Source: Diabetes/Metabolism Research and Reviews - September 1, 2017 Category: Endocrinology Authors: Sascha Heinitz, Paolo Piaggi, Clifton Bogardus, Jonathan Krakoff Tags: RESEARCH ARTICLE Source Type: research

Temporal trends in quality of primary care for patients with type 2 diabetes mellitus: a population ‐based retrospective cohort study after implementation of a quality improvement initiative
ConclusionsCoinciding with implementation of quality improvement initiative, quality of diabetes care improved significantly in the past 5 years, in part attributable to benefits of integrated multidisciplinary diabetes management. (Source: Diabetes/Metabolism Research and Reviews)
Source: Diabetes/Metabolism Research and Reviews - September 1, 2017 Category: Endocrinology Authors: Carlos K.H. Wong, Colman S.C. Fung, Esther Y.T. Yu, Eric Y.F. Wan, Anca K.C. Chan, Cindy L.K. Lam Tags: RESEARCH ARTICLE Source Type: research

Coronary artery bypass grafting versus percutaneous coronary intervention in patients with non ‐insulin treated type 2 diabetes mellitus: a meta‐analysis of randomized controlled trials
ConclusionsIn NITDM patients, our study suggests that CABG surgery is associated with reduced risk of mortality and morbidity, though with increased incidence of stroke compared with PCI. The decision if to have PCI or CABG surgery should factor the risk for stroke of the patients when considering CABG over PCI. Adequately‐powered randomized controlled trials are needed to confirm the results of this meta‐analysis. (Source: Diabetes/Metabolism Research and Reviews)
Source: Diabetes/Metabolism Research and Reviews - September 1, 2017 Category: Endocrinology Authors: Yushu Wang, Meiqin Wen, Junteng Zhou, Yucheng Chen, Qing Zhang Tags: RESEARCH ARTICLE Source Type: research

Association of change in waist circumference and dyslipidemia risk: The Rural Chinese Cohort Study
ConclusionsDynamic change in WC was closely related to the incidence of dyslipidemia in a rural Chinese population. WC reduction could decrease dyslipidemia risk, whereas WC increase may increase the risk. Interventions to control or reduce WC to within the normal range are important for early prevention of dyslipidemia. (Source: Diabetes/Metabolism Research and Reviews)
Source: Diabetes/Metabolism Research and Reviews - September 1, 2017 Category: Endocrinology Authors: Junmei Zhou, Yongcheng Ren, Chongjian Wang, Linlin Li, Lu Zhang, Bingyuan Wang, Yang Zhao, Chengyi Han, Hongyan Zhang, Xiangyu Yang, Xinping Luo, Chao Pang, Lei Yin, Tianping Feng, Jingzhi Zhao, Dongsheng Hu, Ming Zhang Tags: RESEARCH ARTICLE Source Type: research

High genetic risk scores for impaired insulin secretory capacity doubles the risk for type 2 diabetes in Asians and is exacerbated by Western ‐type diets
ConclusionSeventy‐two percent of the Korean population had either medium or high genetic risk scores for impaired insulin secretion, which approximately doubled their risk of type 2 diabetes, and the risk was exacerbated by consuming a low carbohydrate Western‐style diets. (Source: Diabetes/Metabolism Research and Reviews)
Source: Diabetes/Metabolism Research and Reviews - September 1, 2017 Category: Endocrinology Authors: Da Sol Kim, Byoung Chul Kim, James W. Daily, Sunmin Park Tags: RESEARCH ARTICLE Source Type: research

New onset diabetes after kidney transplantation is associated with increased mortality —A retrospective cohort study
ConclusionsNew onset diabetes in kidney transplanted patients is associated with increased mortality compared with kidney transplanted patients without NODAT. (Source: Diabetes/Metabolism Research and Reviews)
Source: Diabetes/Metabolism Research and Reviews - August 30, 2017 Category: Endocrinology Authors: L. Cooper, N. Oz, G. Fishman, T. Shohat, R. Rahamimov, E. Mor, H. Green, A. Grossman Tags: RESEARCH ARTICLE Source Type: research

TNF, TNF Inducers and TNFR2 Agonists: A New Path to Type 1 Diabetes Treatment
ConclusionsThe advancing global clinical trials using BCG combined with mechanistic data on BCGs induction of Tregs suggests value in this generic drug and possible immune reversal of the type 1 diabetic autoimmune process. (Source: Diabetes/Metabolism Research and Reviews)
Source: Diabetes/Metabolism Research and Reviews - August 26, 2017 Category: Endocrinology Authors: Denise L. Faustman Tags: REVIEW ARTICLE Source Type: research

Changing psychosocial determinants of physical activity and diet in women with a history of gestational diabetes mellitus
ConclusionThis lifestyle intervention influenced psychosocial determinants relevant for overweight women with a history of GDM in prevention of T2DM.s (Source: Diabetes/Metabolism Research and Reviews)
Source: Diabetes/Metabolism Research and Reviews - August 26, 2017 Category: Endocrinology Authors: Judith G.M. Jelsma, Mireille N.M. Poppel, Ben J. Smith, Nancy Cinnadaio, Adrian Bauman, Linda Tapsell, N. Wah Cheung, Hidde P. Ploeg Tags: RESEARCH ARTICLE Source Type: research

Recent Findings on Fulminant Type 1 Diabetes
Abstract Fulminant type 1 diabetes (fT1D) is a new subtype of type 1 diabetes proposed by Imagawa in 2000. It is a clinical syndrome characterized by a markedly rapid and almost complete destruction of pancreatic β cells. Metabolic derangement is more severe in this subtype than in autoimmune type 1 diabetes. The incidence of fT1D is associated with HLA DRB1*04:05DQB1*04:01, both innate and acquired immune disorders might contribute to the development of fT1D. The presence of specific innate immune responses to enterovirus infection connected with enhanced adoptive immune pathways responsible for aggressive β cell toxici...
Source: Diabetes/Metabolism Research and Reviews - August 17, 2017 Category: Endocrinology Authors: Lan Liu, Ling Zeng, Dan Sang, Zeyuan Lu, Jie Shen Tags: REVIEW ARTICLE Source Type: research

The association between dysregulated adipocytokines in early pregnancy and development of Gestational Diabetes
ConclusionsDecreased HMW adiponectin and omentin‐1 and increased IL‐6 may enhance sensitivity of early risk prediction tools for women at high risk of GDM. This may allow early identification and opportunities for prevention of GDM and adverse outcomes. Further research is required in large validation studies to confirm these results. (Source: Diabetes/Metabolism Research and Reviews)
Source: Diabetes/Metabolism Research and Reviews - August 14, 2017 Category: Endocrinology Authors: Sally K. Abell, Soulmaz Shorakae, Cheryce L. Harrison, Danielle Hiam, Alba Moreno ‐Asso, Nigel K. Stepto, Barbora De Courten, Helena J. Teede Tags: RESEARCH ARTICLE Source Type: research

Autoantibodies Against PFDN2 Are Associated With An Increased Risk of Type 2 Diabetes: A Case ‐Control Study
ConclusionsAnti‐PFDN2 antibodies are associated with T2DM and might be a useful biomarker. These findings indicate that autoimmunity may play a role in T2DM in SAIs, especially among adults presenting with young onset of disease. (Source: Diabetes/Metabolism Research and Reviews)
Source: Diabetes/Metabolism Research and Reviews - July 21, 2017 Category: Endocrinology Authors: Douglas C. Chang, Paolo Piaggi, Robert L. Hanson, William C. Knowler, Clifton Bogardus, Jonathan Krakoff Tags: RESEARCH ARTICLE Source Type: research

Glycaemic control and the risk of hospitalisation for infection in patients with type 2 diabetes: Hong Kong Diabetes Registry
ConclusionsBurden of serious infection is high in diabetic population and a U‐shape relationship between glycaemia and infection‐related hospitalisation was detected in patients with type 2 diabetes. (Source: Diabetes/Metabolism Research and Reviews)
Source: Diabetes/Metabolism Research and Reviews - July 21, 2017 Category: Endocrinology Authors: Andrea O.Y. Luk, Eric S.H. Lau, Kitty K.T. Cheung, Alice P. Kong, Ronald C.W. Ma, Risa Ozaki, Francis C.C. Chow, Wing ‐Yee So, Juliana C.N. Chan Tags: RESEARCH ARTICLE Source Type: research

Marker of coxsackievirus ‐B4 infection in saliva of patients with type 1 diabetes
ConclusionThere is an anti‐CV‐B4 activity in saliva of patients with type 1 diabetes which may be a useful marker to study the role of CV‐Bs in the pathogenesis of the disease. (Source: Diabetes/Metabolism Research and Reviews)
Source: Diabetes/Metabolism Research and Reviews - July 18, 2017 Category: Endocrinology Authors: F. Badia ‐Boungou, F. Sane, E.K. Alidjinou, M. Ternois, P.A. Opoko, J. Haddad, C. Stukens, C. Lefevre, I. Gueorguieva, M. Hamze, M. Ismail, J. Weill, H.G. Monabéka, E. Bouenizabila, D. Moukassa, A.A. Abena, D. Hober Tags: RESEARCH ARTICLE Source Type: research

Comparative evaluation of probiotics effects on plasma glucose, lipid, and insulin levels in streptozotocin ‐induced diabetic rats
ConclusionThe results of this experiment showed that daily consumption of probiotics can be effective in control of STZ‐induced diabetes and its complications. (Source: Diabetes/Metabolism Research and Reviews)
Source: Diabetes/Metabolism Research and Reviews - July 13, 2017 Category: Endocrinology Authors: Faeghe Memarrast, Soudeh Ghafouri ‐Fard, Sedighe Kolivand, Saeedeh Jafary‐Nodooshan, Nadia Neyazi, Esmaeil Sadroddiny, Elahe Motevaseli Tags: RESEARCH ARTICLE Source Type: research

Intensive insulin therapy combined with metformin is associated with reduction in both glucose variability and nocturnal hypoglycaemia in patients with type 2 diabetes
ConclusionMetformin added to initial CSII or MDI therapy is associated with a reduction in both glucose fluctuation and nocturnal hypoglycaemic risk in patients with type 2 diabetes. (Source: Diabetes/Metabolism Research and Reviews)
Source: Diabetes/Metabolism Research and Reviews - July 13, 2017 Category: Endocrinology Authors: Yifei Zhang, Zhiyun Zhao, Shujie Wang, Wei Zhu, Yiran Jiang, Shouyue Sun, Chen Chen, Kai Wang, Liangshan Mu, Jinyi Cao, Yingxia Zhou, Weiqiong Gu, Jie Hong, Weiqing Wang, Guang Ning Tags: RESEARCH ARTICLE Source Type: research