Enriched environments for rodents and their interaction with nicotine administration.
Authors: Mesa-Gresa P, Ramos-Campos M, Redolat R Abstract An active lifestyle throughout the life cycle seems to delay cognitive aging and dementia and has also been evaluated as an intervention against addiction to cocaine and other drugs of abuse. In epidemiological studies with humans, it has proved difficult to separate the cognitive, social and physical components from other variables that influence lifestyle. Studies in animal models are useful for evaluating the impact of each of these factors and for uncovering the underlying mechanisms of the benefits of complex environments. Preclinical studies h...
Source: Current Drug Abuse Reviews - November 14, 2014 Category: Addiction Tags: Curr Drug Abuse Rev Source Type: research

Editorial: Can Hangover Immunity be Really Claimed?
Authors: Verster JC, de Klerk S, Bervoets AC, Kruisselbrink LD PMID: 25311093 [PubMed - in process] (Source: Current Drug Abuse Reviews)
Source: Current Drug Abuse Reviews - November 14, 2014 Category: Addiction Tags: Curr Drug Abuse Rev Source Type: research

Editorial: Second International Conference on Novel Psychoactive Substances (NPSs): Keynote Addresses and Conference Abstracts.
Authors: Parrott AC, Corazza O, Schifano F, Griffiths P, Sedefov R, Gallegos A, Murray RM, Demetrovics Z, Curran V, Bersani G, Singer LT PMID: 25311094 [PubMed - in process] (Source: Current Drug Abuse Reviews)
Source: Current Drug Abuse Reviews - November 14, 2014 Category: Addiction Tags: Curr Drug Abuse Rev Source Type: research

Conference Proceedings: Second International Conference on Novel Psychoactive Substances (NPS) Swansea, UK; September 12-13th, 2013.
Authors: PMID: 25311095 [PubMed - in process] (Source: Current Drug Abuse Reviews)
Source: Current Drug Abuse Reviews - November 14, 2014 Category: Addiction Tags: Curr Drug Abuse Rev Source Type: research

Treatments for Co-Occurring Depression and Substance Use in Young People: A Systematic Review.
Conclusions:There is a dearth of trials of interventions for co-occurring depression and substance use disorders in young people. The limited data available is promising regarding the overall effectiveness of a psychological counselling approach.Given the importance of early intervention, and the difficulties faced when engaging youth in treatment, there is a need for further focused effort amongst this group. This may require more innovative techniques in intervention design and implementation. Recent advances in Internet- and mobile phone-based therapies present apotential avenue for further research. PMID: 25323...
Source: Current Drug Abuse Reviews - November 14, 2014 Category: Addiction Tags: Curr Drug Abuse Rev Source Type: research

The Changing Face of Tobacco Use Among United States Youth.
Authors: Lauterstein D, Hoshino R, Gordon T, Watkins BX, Weitzman M, Zelikoff J Abstract Tobacco use, primarily in the form of cigarettes, is the leading cause of preventable morbidity and mortality in the United States (U.S.). The adverse effects of tobacco use began to be recognized in the 1940's and new hazards of active smoking and secondhand smoke (SHS) exposure from cigarettes continue to be identified to this day. This has led to a sustained and wide-ranging array of highly effective regulatory, public health, and clinical efforts that have been informed by extensive scientific data, resulting in ma...
Source: Current Drug Abuse Reviews - November 14, 2014 Category: Addiction Tags: Curr Drug Abuse Rev Source Type: research

Current Management of Alcoholic Liver Disease.
Authors: Singal AK, Jampana SC Abstract Alcoholic liver disease accounts for significant economic burden with second most common cause for liver transplantation in the US. Although alcohol abstinence is most crucial, morbidity and mortality occur amongst those with continuing alcohol intake and with established end stage liver disease due to lack of specific treatment modalities to manage this disease. Patients with severe acute alcoholic hepatitis, a distinct subset of alcoholic liver disease have a potential for mortality in about 25% within about 1 month despite treatment with available specific agents ...
Source: Current Drug Abuse Reviews - November 14, 2014 Category: Addiction Tags: Curr Drug Abuse Rev Source Type: research

Opioid Neonatal Abstinence Syndrome: controversies and implications for practice.
Authors: Wolff K, Perez-Montejano R Abstract The Opioid Neonatal Abstinence Syndrome (NAS) is a term used to describe a cluster of signs and symptoms seen in infants experiencing withdrawal from opioid drugs. Despite a substantial literature the relationship between maternal methadone dose, NAS and the method of assessment of NAS symptoms has not been agreed. The following review will address current and historical controversies surrounding these issues and will examine the evidence concerned with the evaluation of neonates exposed to methadone in utero. The key findings are as follows: A variety of NAS sc...
Source: Current Drug Abuse Reviews - November 14, 2014 Category: Addiction Tags: Curr Drug Abuse Rev Source Type: research

Validity of alcohol screening instruments in general population gender studies: an analytical review.
Authors: de Oliveira JB, Kerr-Correa F, Pereira Lima MC, Bertolote JM, Ferreira Santos JL, Oliveira J Abstract The present study is an analytical review of the methodology used in studies of efficacy of screening instruments to detect harmful use/ alcohol dependence according to the gender in population surveys. Systematic review of bibliography was done, using data from Web of Science, Pubmed and PsycInfo. Population studies were included without date range, in English, Spanish or Portuguese languages, with sample of adults, evaluating psychometric characteristics of any alcohol screening instrument, wher...
Source: Current Drug Abuse Reviews - November 14, 2014 Category: Addiction Tags: Curr Drug Abuse Rev Source Type: research