Modifying splice site usage with ModCon: maintaining the genetic code while changing the underlying mRNP code
Publication date: Available online 21 May 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Johannes Ptok, Lisa Müller, Philipp Niklas Ostermann, Anastasia Richie, Alexander T. Dilthey, Stephan Theiss, Heiner Schaal (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - May 22, 2021 Category: Biotechnology Source Type: research

p-Nitrophenyl Esters Provide New Insights and Applications for the Thiolase Enzyme OleA
Publication date: Available online 21 May 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Megan D. Smith, Lambros Tassoulas, Troy A. Biernath, Jack E. Richman, Kelly Aukema, Lawrence P. Wackett (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - May 22, 2021 Category: Biotechnology Source Type: research

Distinguishing between PTEN clinical phenotypes through mutation analysis
Publication date: Available online 21 May 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Stephanie Portelli, Lucy Barr, Alex G.C. de Sá, Douglas E.V. Pires, David B. Ascher (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - May 22, 2021 Category: Biotechnology Source Type: research

Metabolites as predictive biomarkers for Trypanosoma cruzi exposure in triatomine bugs
Publication date: Available online 21 May 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Fanny E. Eberhard, Sven Klimpel, Alessandra A. Guarneri, Nicholas J. Tobias (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - May 22, 2021 Category: Biotechnology Source Type: research

Endogenous modulators of neurotrophin signaling: Landscape of the transient ATP-NGF interactions
Publication date: 2021Source: Computational and Structural Biotechnology Journal, Volume 19Author(s): Francesca Paoletti, Franci Merzel, Alberto Cassetta, Iza Ogris, Sonia Covaceuszach, Jože Grdadolnik, Doriano Lamba, Simona Golič Grdadolnik (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - May 21, 2021 Category: Biotechnology Source Type: research

Machine learning applied to serum and cerebrospinal fluid metabolomes revealed altered arginine metabolism in neonatal sepsis with meningoencephalitis
Publication date: Available online 18 May 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Peng Zhang, Zhangxing Wang, Huixian Qiu, Wenhao Zhou, Mingbang Wang, Guoqiang Cheng (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - May 19, 2021 Category: Biotechnology Source Type: research

Learning from –omics strategies applied to uncover Haemophilus influenzae host-pathogen interactions: current status and perspectives
Publication date: Available online 15 May 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Nahikari López-López, Celia Gil-Campillo, Roberto Díez-Martínez, Junkal Garmendia (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - May 16, 2021 Category: Biotechnology Source Type: research

Genome-scale mechanistic modeling of signaling pathways made easy: a Bioconductor / cytoscape / web server framework for the analysis of omic data
Publication date: Available online 15 May 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Kinza Rian, Marta R. Hidalgo, Cankut Çubuk, Matias M. Falco, Carlos Loucera, Marina Esteban-Medina, Inmaculada Alamo-Alvarez, María Peña-Chilet, Joaquín Dopazo (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - May 16, 2021 Category: Biotechnology Source Type: research

Versatile control of the CDC48 segregase by the plant UBX-containing (PUX) proteins
Publication date: Available online 14 May 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Junrui Zhang, Alexandra I. Vancea, Umar F. Shahul Hameed, Stefan T. Arold (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - May 15, 2021 Category: Biotechnology Source Type: research

Image-driven classification of functioning and nonfunctioning pituitary adenoma by deep convolutional neural networks
Publication date: Available online 14 May 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Hongyu Li, Qi Zhao, Yihua Zhang, Ke Sai, Lunshan Xu, Yonggao Mou, Yubin Xie, Jian Ren, Xiaobing Jiang (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - May 15, 2021 Category: Biotechnology Source Type: research

Making fundamental scientific discoveries by combining information from literature, databases, and computational tools – An example
Publication date: Available online 14 May 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Bastian Stielow, Clara Simon, Robert Liefke (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - May 14, 2021 Category: Biotechnology Source Type: research

A combined evolutionary and structural approach to disclose the primary structural determinants essential for proneurotrophins biological functions
Publication date: Available online 13 May 2021Source: Computational and Structural Biotechnology JournalAuthor(s): S. Covaceuszach, L.Y. Peche, P.V. Konarev, D. Lamba (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - May 13, 2021 Category: Biotechnology Source Type: research

Computational optimization of angiotensin-converting enzyme 2 for SARS-CoV-2 Spike molecular recognition.
Publication date: Available online 13 May 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Lorenzo Di Rienzo, Michele Monti, Edoardo Milanetti, Mattia Miotto, Alberto Boffi, Gian Gaetano Tartaglia, Giancarlo Ruocco (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - May 13, 2021 Category: Biotechnology Source Type: research

DeepOmix: A scalable and interpretable multi-omics deep learning framework and application in cancer survival analysis
Publication date: 2021Source: Computational and Structural Biotechnology Journal, Volume 19Author(s): Lianhe Zhao, Qiongye Dong, Chunlong Luo, Yang Wu, Dechao Bu, Xiaoning Qi, Yufan Luo, Yi Zhao (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - May 12, 2021 Category: Biotechnology Source Type: research

Modelling of SHMT1 riboregulation predicts dynamic changes of serine and glycine levels across cellular compartments
Publication date: Available online 12 May 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Michele Monti, Giulia Guiducci, Alessio Paone, Serena Rinaldo, Giorgio Giardina, Francesca Romana Liberati, Francesca Cutruzzolá, Gian Gaetano Tartaglia (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - May 12, 2021 Category: Biotechnology Source Type: research