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Cytotoxic, Antimutagenic, and Antioxidant Activities of Methanolic Extract and Chalcone Dimers (Lophirones B and C) Derived From Lophira alata (Van Tiegh. Ex Keay) Stem Bark
The cytotoxic, antimutagenic, and antioxidant activities of methanolic extract and lophirones B and C derived from Lophira alata stem bark were evaluated. The extract and lophirones B and C significantly (P < .05) reduced the viability of Ehrlich ascites carcinoma cells. There were concentration-dependent reduction in 4-nitro-o-aminophenylenediamine and benzo[a]pyrene–induced frame shift mutation as well as aflatoxin B1–induced base pair substitution by the extract and lophirones B and C. The extract and lophirones B and C concentration dependently scavenged DPPH radical, superoxide anion radical, hydrogen p...
Source: Complementary Health Practice Review - December 20, 2013 Category: Complementary Medicine Authors: Ajiboye, T. O., Yakubu, M. T., Oladiji, A. T. Tags: Original Articles Source Type: research

Clinical and Structural Effects of Traditional Chinese Medicine and the Herbal Preparation, Iberogast, in a Rat Model of Ulcerative Colitis
Plant-sourced formulations such as Iberogast and the traditional Chinese medicine formulation, Cmed, purportedly possess anti-inflammatory and radical scavenging properties. We investigated Iberogast and Cmed, independently, for their potential to decrease the severity of the large bowel inflammatory disorder, ulcerative colitis. Sprague Dawley rats (n = 8/group) received daily 1 mL gavages (days 0-13) of water, Iberogast (100 μL/200 μL), or Cmed (10 mg/20 mg). Rats ingested 2% dextran sulfate sodium or water ad libitum for 7 days commencing on day 5. Dextran sulfate sodium administration increased disease activity i...
Source: Complementary Health Practice Review - December 20, 2013 Category: Complementary Medicine Authors: Mashtoub, S., Hoang, B. V., Vu, M., Lymn, K. A., Feinle-Bisset, C., Howarth, G. S. Tags: Original Articles Source Type: research

Retrospective Case Analyses of Two People With Cancer Who Followed the Bill Henderson Protocol
Conclusions: The 2 cases provide a preliminary, detailed description of Bill Henderson Protocol adherence. They do not provide clear evidence of the protocol’s effectiveness but do suggest further research be undertaken to assess the extent to which the Bill Henderson Protocol is followed in real-world settings, including consideration of adherence, side effects, and outcomes. (Source: Complementary Health Practice Review)
Source: Complementary Health Practice Review - December 20, 2013 Category: Complementary Medicine Authors: Page, S. A., Bell, L. H., Mannion, C., Verhoef, M. J. Tags: Original Articles Source Type: research

Green Coffee for Pharmacological Weight Loss
This review article evaluates if clinical data support the use of green coffee for weight loss. A literature search was conducted that yielded 5 clinical trials and 1 meta-analysis. Studies were evaluated for quality in accordance to clinical practice and US Food and Drug Administration guidelines. The amount of weight loss ranged from approximately 1 to 8 kg, with the meta-analysis finding a statistically significant difference in body weight, with a mean difference of –2.47 kg between green coffee and placebo (95% confidence interval = –4.23 to –0.72). The duration of trials varied between 4 and 12...
Source: Complementary Health Practice Review - September 13, 2013 Category: Complementary Medicine Authors: Buchanan, R., Beckett, R. D. Tags: Topical Review Articles Source Type: research

Oxygen Consumption Changes With Yoga Practices: A Systematic Review
Oxygen consumption varies with physical and mental activity as well as pathological conditions. Although there is a strong relationship between yoga and metabolic parameters, the relationship between yoga and oxygen consumption has not yet been formally reviewed. This systematic review attempted to include all studies of yoga that also measured oxygen consumption or metabolic rate as an outcome. A total of 58 studies were located involving between 1 and 104 subjects (average 21). The studies were generally of poor methodological quality and demonstrated great heterogeneity with different experimental designs, yoga practice...
Source: Complementary Health Practice Review - September 13, 2013 Category: Complementary Medicine Authors: Tyagi, A., Cohen, M. Tags: Topical Review Articles Source Type: research

The Role of Essential Fatty Acids in Human Health
Fatty acid research began about 90 years ago but intensified in recent years. Essential fatty acids (linoleic and α-linolenic) must come from diet. Other fatty acids may come from diet or may be synthesized. Fatty acids are major components of cell membrane structure, modulate gene transcription, function as cytokine precursors, and serve as energy sources in complex, interconnected systems. It is increasingly apparent that dietary fatty acids influence these vital functions and affect human health. While the strongest evidence for influence is found in cardiovascular disease and mental health, many additional condit...
Source: Complementary Health Practice Review - September 13, 2013 Category: Complementary Medicine Authors: Glick, N. R., Fischer, M. H. Tags: Topical Review Articles Source Type: research

The Effect of Hawthorn Extract on Coronary Flow
Hawthorn extract has been used for heart failure and may decrease cardiac cell injury and improve cardiac function. One proposed mechanism for hawthorn action is vasodilation. We hypothesized that hawthorn extract would increase coronary blood flow in isolated perfused rat hearts. Coronary flow was measured in nonworking perfused rat hearts (Langendorff, constant pressure) using a flow probe; data were collected electronically in real time. Hawthorn extract showed an early (30-120 seconds) vasodilation, followed by a later (3-5 minutes) decrease in coronary flow. Maximum vasodilation occurred with 240 μg/mL hawthorn ext...
Source: Complementary Health Practice Review - September 13, 2013 Category: Complementary Medicine Authors: Dood, K. P., Frey, A. D., Geisbuhler, T. P. Tags: Original Articles Source Type: research

Hypolipidemic Effects of a Proprietary Commiphora Mukul Gum Resin Extract and Medium-Chain Triglyceride Preparation (GU-MCT810)
The hypolipidemic effects of the poorly soluble ayurvedic resin guggul, especially the molecular targets and mechanism, have not been well investigated to date. In the present study, we have formulated a liquid product, GU-MCT810, composed of a proprietary Commiphora mukul gum resin extract and medium-chain triglyceride and investigated its hypolipidemic effects in vitro. Treatment of HepG2 cells significantly reduced low-density lipoprotein cholesterol and increased the high-density lipoprotein/low-density lipoprotein ratio. GU-MCT810 showed direct inhibition of HMG-CoA reductase activity in a dose-dependent manner and co...
Source: Complementary Health Practice Review - September 13, 2013 Category: Complementary Medicine Authors: Ramachandran, C., Nair, S. M., Quirrin, K.-W., Melnick, S. J. Tags: Original Articles Source Type: research

Mindfulness-Based Stress Reduction and Change in Health-Related Behaviors
In conclusion, mindfulness training promotes favorable changes in selected health-related behaviors deserving further study through randomized controlled trials. (Source: Complementary Health Practice Review)
Source: Complementary Health Practice Review - September 13, 2013 Category: Complementary Medicine Authors: Salmoirago-Blotcher, E., Hunsinger, M., Morgan, L., Fischer, D., Carmody, J. Tags: Original Articles Source Type: research

Anthocyanin-Rich Purple Corn Extract and Its Effects on the Blood Pressure of Adults
This small-scale pilot study studied the potential benefit of taking a concentrated dose of anthocyanin 300 mg once a day for 3 weeks (purple corn extract) on blood pressure among untreated Peruvian adults with mild-to-moderate hypertension. A double-blind placebo-controlled randomized crossover trial using intention-to-treat analysis was conducted on 30 healthy men and women who received care at the Dos de Mayo Hospital (Lima, Peru) between September 2010 and August 2011. The 4-phase study compared blood pressure readings on placebo and on purple corn extract. Blood pressure readings decreased from baseline levels to end ...
Source: Complementary Health Practice Review - September 13, 2013 Category: Complementary Medicine Authors: Finkel, M. L., Sanchez, S., Mak, T., Granstein, J., Lefkowitz, A. Tags: Original Articles Source Type: research

Book/Media Review of Transcending Dementia Through the TTAP Method: A New Psychology of Art, Brain, and Cognition by Linda Levine Madori
(Source: Complementary Health Practice Review)
Source: Complementary Health Practice Review - June 21, 2013 Category: Complementary Medicine Authors: Rolli, M. L. Tags: Book/Media Review Source Type: research

Are the Current Complementary and Alternative Therapies Available for the Treatment of Low Back Pain and Chronic Fatigue Syndrome Reliable Clinically? A Review of the Literature
This article assesses the clinical reliability of complementary and alternative therapies in the treatment of low back pain and chronic fatigue syndrome using the existing accessible literature. Multiple bibliographic databases that include medical, general health care, and natural medicine literature were searched for relevant terms and conclusions. The authors examined all abstracts obtained through the search and reviewed the full text of the relevant articles along with the additional supporting articles that resulted from the search. It is observed from the literature that most of the complementary and alternative tre...
Source: Complementary Health Practice Review - June 21, 2013 Category: Complementary Medicine Authors: Yee, C. W., Chellappan, D. K. Tags: Topical Review Articles Source Type: research

Tai Chi as an Alternative and Complementary Therapy for Patients With Asthma and Chronic Obstructive Pulmonary Disease: A Systematic Review
Chronic obstructive pulmonary disease and asthma are the third ranking cause of death worldwide. A systematic review was conducted to determine the efficacy of tai chi as a therapy to relieve symptoms of chronic obstructive pulmonary disease and/or asthma. Inclusion criteria were (a) published in the English language, (b) between the period January 2008 and July 2012, (c) included tai chi or any form of modified tai chi as a therapy in an intervention, (d) used any quantitative study design, and (e) measured chronic obstructive pulmonary disease and/or asthma as an outcome. A total of 5 interventions from 6 studies met the...
Source: Complementary Health Practice Review - June 21, 2013 Category: Complementary Medicine Authors: Sharma, M., Haider, T. Tags: Topical Review Articles Source Type: research

Newly Developed Synbiotics and the Chemotherapy-Damaged Gut
Mucositis is a common side-effect of cancer chemotherapy and radiotherapy. Features of mucositis include erythema, ulceration, and inflammation of the gastrointestinal tract accompanied by clinical symptoms of abdominal pain and digestive disturbances. New treatment strategies are required. Experimental evidence is accumulating showing therapeutic promise for new nutraceutical agents including probiotic bacteria, probiotic-derived factors, prebiotics, and plant extracts. However, the targeted development of new combinations of these agents (synbiotics) to combat mucositis remains largely unexplored. The current review addr...
Source: Complementary Health Practice Review - June 21, 2013 Category: Complementary Medicine Authors: Wang, H., Bastian, S. E. P., Howarth, G. S. Tags: Topical Review Articles Source Type: research

Usage of Complementary and Alternative Medicine among Severe Hemophilia A Patients in India
Documented evidence of the usage of complementary and alternative medicine among patients with rare disease such as hemophilia is limited. Therefore, we explored the types of complementary and alternative medicines used, the associated sociodemographic and clinical factors, and the cost and reasons for usage among severe hemophilia A patients in India. Our study demonstrates an increased usage of complementary and alternative medicine (42.3%) among hemophiliacs. Significant factors associated with usage of these therapies were economic status, comorbidity status, and education of head of households. Among users of compleme...
Source: Complementary Health Practice Review - June 21, 2013 Category: Complementary Medicine Authors: Jadhav, U., Mukherjee, K., Thakur, H. Tags: Original Articles Source Type: research