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Comparison of the Protective Effects of Melatonin and Silymarin Against Gentamicin-Induced Nephrotoxicity in Rats
This study compared the possible protective effects of silymarin and melatonin against gentamicin (GEN)-induced nephrotoxicity in rats. Rats were allocated to 6 groups: Group I, control group; Groups II and III, administered with silymarin or melatonin; Group IV, injected with GEN; and Groups V and VI, administered with silymarin or melatonin, and then injected with GEN. Compared with the rats in the control group, all rats injected with GEN significantly presented elevated levels of serum creatinine and urea that was accompanied by an increase in relative kidney weight, increase in renal reactive oxygen species (ROS) and ...
Source: Complementary Health Practice Review - September 27, 2016 Category: Complementary Medicine Authors: Ghaznavi, H., Mehrzadi, S., Dormanesh, B., Tabatabaei, S. M. T. H., Vahedi, H., Hosseinzadeh, A., Pazoki-Toroudi, H., Rashidian, A. Tags: E-only Articles Source Type: research

A Member of Complementary Medicinal Food: Anatolian Royal Jellies, Their Chemical Compositions, and Antioxidant Properties
This study investigated various chemical and antioxidant properties of Anatolian royal jelly samples. Moisture, pH, total protein, 10-hydroxy-2-decenoic acid (10-HDA) and sugars were analyzed from 18 samples. Total phenolic contents, ferric reducing antioxidant capacity and 2,2-diphenyl-1-picryhydrazyl (DPPH) free radical scavenging activity were measured as antioxidant determinants. 10-HDA contents and total protein content of fresh weight ranged between 1.0% and 3.9%, and 11.4% and 15.8%, respectively. The main sugars detected were glucose and fructose. Maltose, trehalose, and melibiose were detected at less than 1.0% in...
Source: Complementary Health Practice Review - September 27, 2016 Category: Complementary Medicine Authors: Kolayli, S., Sahin, H., Can, Z., Yildiz, O., Malkoc, M., Asadov, A. Tags: E-only Articles Source Type: research

Protective Effect of Ocimum basilicum Essential Oil Against Acetic Acid-Induced Colitis in Rats
This study investigates the ameliorative effect of Ocimum basilicum essential oil on an acetic acid–induced colitis model in rats. Ocimum basilicum essential oil with 2 doses (200 and 400 μL/kg) significantly ameliorated wet weight/length ratio of colonic tissue compared to the control group. Higher doses of essential oil (200 and 400 μL/kg) significantly reduced ulcer severity, ulcer area, and ulcer index. On the other hand, histological examination revealed the diminution of total colitis index as a marker for inflammatory cell infiltration in the colonic segments of rats treated with Ocimum basilicum essenti...
Source: Complementary Health Practice Review - September 27, 2016 Category: Complementary Medicine Authors: Rashidian, A., Roohi, P., Mehrzadi, S., Ghannadi, A. R., Minaiyan, M. Tags: E-only Articles Source Type: research

Anticonvulsant Activity of Hydroalcoholic Extract of Citrullus colocynthis Fruit: Involvement of Benzodiazepine and Opioid Receptors
This study investigated the anticonvulsant activity of Citrullus colocynthis fruit extract used traditionally in the treatment of convulsion. Albino mice were pretreated with extract in different doses (10, 25, 50, and 100 mg/kg), prior to injection of pentylenetetrazole. Animals received pretreatments with naloxone and flumazenil to further clarify the mechanisms of anticonvulsant action. The total flavonoid content of Citrullus colocynthis extract was also determined. Citrullus colocynthis hydroalcoholic extract with doses 25 and 50 mg/kg prolonged the onset of seizures and decreased the duration compared with control gr...
Source: Complementary Health Practice Review - September 27, 2016 Category: Complementary Medicine Authors: Mehrzadi, S., Shojaii, A., Pur, S. A., Motevalian, M. Tags: E-only Articles Source Type: research

Antidiabetic and Antihyperlipidemic Effects of Ethanol Extract of Rosa canina L. fruit on Diabetic Rats: An Experimental Study With Histopathological Evaluations
This study was undertaken to evaluate the antidiabetic and antihyperlipidemic effects of Rosa canina fruit extract in streptozotocin induced diabetic rats. The results showed oral administration of Rosa canina fruit extract significantly ameliorated the high levels of blood glucose compared with the control group. Serum triglyceride levels significantly decreased by the administration of Rosa canina extract compared with control. Histopathological examinations showed that the Rosa canina extract improved islets necrotic and regenerated pancreatic islet cells. Rosa canina extract has the antihyperglycemic and antihyperlipid...
Source: Complementary Health Practice Review - September 27, 2016 Category: Complementary Medicine Authors: Taghizadeh, M., Rashidi, A. A., Taherian, A. A., Vakili, Z., Sajad Sajadian, M., Ghardashi, M. Tags: E-only Articles Source Type: research

Immunomodulatory Effects of Psyllium Extract on Helicobacter pylori Interaction With Gastric Epithelial Cells
Natural plant product Psyllium has anti-inflammatory activity that can modulate the function of cytokines. We determined the effect of Psyllium husk extract on interleukin (IL)-8 and NF-B secretion by gastric epithelial cells in response to Helicobacter pylori. Human gastric adenocarcinoma cell line (AGS) cells were pretreated with Psyllium extract in different concentrations before H pylori infection. Cell culture supernatant was analyzed for IL-8 and NF-B by ELISA. RNA from cells was used for real-time polymerase chain reaction for messenger RNA expression of IL-8. Psyllium extract 5 and 10 μg/mL markedly (P < .001...
Source: Complementary Health Practice Review - September 27, 2016 Category: Complementary Medicine Authors: Yakoob, J., Jafri, W., Mehmood, M. H., Abbas, Z., Tariq, K. Tags: E-only Articles Source Type: research

Antioxidative Properties and Effect of Quercetin and Its Glycosylated Form (Rutin) on Acetylcholinesterase and Butyrylcholinesterase Activities
This study sought to investigate the anticholinesterase and antioxidative properties of quercetin and its glycosylated conjugate, rutin. The in vitro inhibition of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) activities, inhibition of Fe2+-induced lipid peroxidation in rat’s brain homogenates, radicals scavenging, and Fe2+-chelating abilities of the flavonoids were investigated in vitro with concentrations of the samples ranging from 0.06 to 0.6 mM. Quercetin had significantly higher AChE and BChE inhibitory abilities than rutin. Quercetin also had stronger inhibition of Fe2+-induced lipid peroxidatio...
Source: Complementary Health Practice Review - September 27, 2016 Category: Complementary Medicine Authors: Ademosun, A. O., Oboh, G., Bello, F., Ayeni, P. O. Tags: E-only Articles Source Type: research

Shemamruthaa, a Herbal Formulation Induces Apoptosis in Breast Cancer Cells and Inhibits Tumor Progression in Rats
This study investigates the anticancer activity of Shemamruthaa in breast cancer (MDA-MB 231) cell lines and its cancer therapeutic potential in 7,12-dimethylbenz[a]anthracene induced breast cancer rats. Results of MTT, trypan blue, and apoptotic marker assays suggested that Shemamruthaa can induce cytotoxicity in cancer cells, in a concentration- and time-dependent manner. Oral administration of Shemamruthaa effectively suppressed the tumor progression as evidenced by decrease in tumor volume and modulation of oxidant-antioxidant status and resulted in extended life span. Gas chromatography–mass spectrometry and hig...
Source: Complementary Health Practice Review - September 27, 2016 Category: Complementary Medicine Authors: Purushothaman, A., Nandhakumar, E., Shanthi, P., Sachidanandam, T. P. Tags: E-only Articles Source Type: research

Lifestyle Methods for Prevention of Alzheimers Disease From the Perspective of Traditional Persian Medicine
Alzheimer’s disease is considered as a major problem for society health since it affects interpersonal and social relationships. With regard to the global attention toward complementary medicine, search for preventive, diagnostic, and treatment strategies in complementary medicine schools such as the old dynamic doctrine of traditional Persian medicine seems to be necessary. In this type of medicine, description and analysis of the disease and preventive and treatment methods have great importance. The present study provides a useful classification of recommendations for prevention and control of Alzheimer’s di...
Source: Complementary Health Practice Review - May 25, 2016 Category: Complementary Medicine Authors: Tajadini, H., Choopani, R., Saifadini, R. Tags: Topical Review Articles Source Type: research

Scientific Evaluation of Pharmacological Treatment of Osteoarthritis in the Canon of Medicine
Osteoarthritis is the most common articular disease worldwide. Nonetheless, common osteoarthritis treatments are either not effective or associated with side effects. Now the materials derived from plants have found a relevant place in drug discovery. Until the mid-18th century, osteoarthritis in all medical schools worldwide had been managed as general arthritis. Avicenna, the famous scholar of Iranian traditional medicine has provided a long list of herbs that have been used traditionally to treat arthritis. To gain this worthy list, we searched his most famous medical masterpiece: Canon of Medicine. Some of these materi...
Source: Complementary Health Practice Review - May 25, 2016 Category: Complementary Medicine Authors: Choopani, R., Ghourchian, A., Hajimehdipoor, H., Kamalinejad, M. Tags: Topical Review Articles Source Type: research

Obesity Phytotherapy: Review of Native Herbs Used in Traditional Medicine for Obesity
Obesity is an important disorders due to which 25 million deaths occur annually worldwide. Synthetic drugs for weight loss have low efficacy and high side effects. Apart from synthetic drugs in modern medicine, various other methods including the use of herbal medications are used to induce weight loss. Cambodia hoodia, green tea, Citrus aurantium, white beans, fenugreek, caffeine, ephedrine, capsaicin, yohimbine, chitosan, fitostreols, and guar gum have been studied in clinical trials and their effects have been confirmed. It seems necessary to study more to determine the effectiveness and safety of medicinal plants and h...
Source: Complementary Health Practice Review - May 25, 2016 Category: Complementary Medicine Authors: Bahmani, M., Eftekhari, Z., Saki, K., Fazeli-Moghadam, E., Jelodari, M., Rafieian-Kopaei, M. Tags: Topical Review Articles Source Type: research

A Review Study on Punica granatum L
Punica granatum L (pomegranate) is a deciduous shrub, native to Iran. Nowadays, besides its use as a fruit, its medicinal properties have attracted the interest of researchers of many countries. Pomegranate fruit has medicinal properties such as anti-inflammatory and antibacterial activities. The pomegranate seed oil has inhibitory effect on skin and breast cancers. The pomegranate seed oil has phytoestrogenic compounds and the fruit is rich in phenolic compounds with strong antioxidant activity. Ellagic acid is one of the main components of pomegranate with phenolic structure and antioxidant activity. This review article ...
Source: Complementary Health Practice Review - May 25, 2016 Category: Complementary Medicine Authors: Shaygannia, E., Bahmani, M., Zamanzad, B., Rafieian-Kopaei, M. Tags: Topical Review Articles Source Type: research

Assessment of Quality of Life in Patients With Skin Disorders Undergoing Ayurvedic Panchakarma (Biopurification) as Management
Conclusion. Study concludes that there is improvement in quality of life among patients with skin disease after undergoing Ayurveda purification therapies. (Source: Complementary Health Practice Review)
Source: Complementary Health Practice Review - May 25, 2016 Category: Complementary Medicine Authors: Deshpande, H., Shivakumar, , Kavita, M. B., Tripathy, T. B., Chaturvedi, A. Tags: Original Articles Source Type: research

The Evaluation of Curative Effect of Acupuncture: A Review of Systematic and Meta-Analysis Studies
The present study attempts to critically evaluate previously published research articles on the efficiency of acupuncture in the treatment of diseases. First, 35 systematic reviews or meta-analysis were found in the Cochrane database. Second, 54 related articles were selected by searching important scientific databases. Based on the results obtained regarding the efficacy of acupuncture for the treatment of various diseases, the articles were divided into 3 groups. The first group of articles confirmed the efficacy of treatment by acupuncture. In the second group of articles, the therapeutic effect of acupuncture was shown...
Source: Complementary Health Practice Review - May 25, 2016 Category: Complementary Medicine Authors: Salehi, A., Marzban, M., Imanieh, M. H. Tags: Original Articles Source Type: research

Effect and Mechanism of Virechana Karma (Therapeutic Purgation) Over Fructose-Induced Metabolic Syndrome: An Experimental Study
Conclusion. Experimental evaluation showed decrease in fatty acid in the storage like liver, kidney, heart, and muscle adipose tissue can indirectly increase the insulin sensitivity in insulin receptor present at skeletal muscles. (Source: Complementary Health Practice Review)
Source: Complementary Health Practice Review - May 25, 2016 Category: Complementary Medicine Authors: Chaturvedi, A., Rao, P. N., Kumar, M. A., Ravishankar, B., Rao, N., Ravi, M. Tags: Original Articles Source Type: research