Early Detection and Treatment of the Vulnerable Coronary Plaque: Can We Prevent Acute Coronary Syndromes? [Advances in Cardiovascular Imaging]
Early identification and treatment of the vulnerable plaque, that is, a coronary artery lesion with a high likelihood of rupture leading to an acute coronary syndrome, have gained great interest in the cardiovascular research field. Postmortem studies have identified clear morphological characteristics associated with plaque rupture. Recent advances in invasive and noninvasive coronary imaging techniques have empowered the clinician to identify suspected vulnerable plaques in vivo and paved the way for the evaluation of therapeutic agents targeted at reducing plaque vulnerability. Local treatment of vulnerable plaques by p...
Source: Circulation: Cardiovascular Imaging - May 8, 2017 Category: Radiology Authors: Bom, M. J., van der Heijden, D. J., Kedhi, E., van der Heyden, J., Meuwissen, M., Knaapen, P., Timmer, S. A. J., van Royen, N. Tags: Computerized Tomography (CT), Imaging, Magnetic Resonance Imaging (MRI), Nuclear Cardiology and PET, Optical Coherence Tomography (OCT) Advances in Cardiovascular Imaging Source Type: research

A Good Heart Is Hard to Find: Even Early in Hypertrophic Cardiomyopathy [Editorial]
(Source: Circulation: Cardiovascular Imaging)
Source: Circulation: Cardiovascular Imaging - May 5, 2017 Category: Radiology Authors: Lu, D.-Y., Abraham, T. P. Tags: Cardiomyopathy Editorial Source Type: research

Disease Stage-Dependent Changes in Cardiac Contractile Performance and Oxygen Utilization Underlie Reduced Myocardial Efficiency in Human Inherited Hypertrophic Cardiomyopathy [Cardiomyopathies]
Conclusions— Different mechanisms underlie reduced MEE at the early and advanced stage of hypertrophic cardiomyopathy. The initial increase and subsequent reduction in myocardial oxygen consumption during disease progression indicates that energy deficiency is a primary mutation-related event, whereas mechanisms secondary to disease remodeling underlie low MEE in HOCM. Our data highlight that the benefit of therapies to improve energetic status of the heart may vary depending on the disease stage and that treatment should be initiated before cardiac remodeling. (Source: Circulation: Cardiovascular Imaging)
Source: Circulation: Cardiovascular Imaging - May 5, 2017 Category: Radiology Authors: Guclu, A., Knaapen, P., Harms, H. J., Parbhudayal, R. Y., Michels, M., Lammertsma, A. A., van Rossum, A. C., Germans, T., van der Velden, J. Tags: Cardiomyopathy, Heart Failure, Hypertrophy, Remodeling, Valvular Heart Disease Cardiomyopathies Source Type: research

Revisiting Coronary Artery Calcium and Incident Dementia [Editorials]
(Source: Circulation: Cardiovascular Imaging)
Source: Circulation: Cardiovascular Imaging - May 2, 2017 Category: Radiology Authors: Lu, M. T. Tags: Aging, Cardiovascular Disease, Risk Factors Editorials Source Type: research

Coronary Artery Calcium and Risk of Dementia in MESA (Multi-Ethnic Study of Atherosclerosis) [Epidemiology]
Conclusions— Higher baseline CAC was significantly associated with increased risk of dementia independent of vascular risk factor, APOE-4, and incident stroke. This is consistent with a hypothesis that vascular injuries play a role in the development of dementia. (Source: Circulation: Cardiovascular Imaging)
Source: Circulation: Cardiovascular Imaging - May 2, 2017 Category: Radiology Authors: Fujiyoshi, A., Jacobs, D. R., Fitzpatrick, A. L., Alonso, A., Duprez, D. A., Sharrett, A. R., Seeman, T., Blaha, M. J., Luchsinger, J. A., Rapp, S. R. Tags: Epidemiology Source Type: research

Imaging to Diagnose and Manage Patients in Heart Failure With Reduced Ejection Fraction [How to Use Imaging]
(Source: Circulation: Cardiovascular Imaging)
Source: Circulation: Cardiovascular Imaging - April 11, 2017 Category: Radiology Authors: Nagueh, S. F., Chang, S. M., Nabi, F., Shah, D. J., Estep, J. D. Tags: Diagnostic Testing, Echocardiography, Imaging, Magnetic Resonance Imaging (MRI), Nuclear Cardiology and PET How to Use Imaging Source Type: research

Chronic Total Occlusion Percutaneous Coronary Intervention: Preparation Is the Key to Success [Editorials]
(Source: Circulation: Cardiovascular Imaging)
Source: Circulation: Cardiovascular Imaging - April 7, 2017 Category: Radiology Authors: Sawlani, N., Bhatt, D. L. Tags: Catheter-Based Coronary and Valvular Interventions Editorials Source Type: research

Stress Computed Tomographic Perfusion: Are We Ready for the Green Light? [Editorials]
(Source: Circulation: Cardiovascular Imaging)
Source: Circulation: Cardiovascular Imaging - April 7, 2017 Category: Radiology Authors: Pontone, G., Rabbat, M. G., Guaricci, A. I. Tags: Computerized Tomography (CT), Imaging Editorials Source Type: research

Coronary Computed Tomography Angiography Predicts Guidewire Crossing and Success of Percutaneous Intervention for Chronic Total Occlusion: Korean Multicenter CTO CT Registry Score as a Tool for Assessing Difficulty in Chronic Total Occlusion Percutaneous Coronary Intervention [Coronary Artery Disease]
Conclusions— KCCT scoring could predict successful guidewire crossing ≤30 minutes and also procedural success. KCCT scoring may enable noninvasive grading difficulty of CTO percutaneous coronary intervention. (Source: Circulation: Cardiovascular Imaging)
Source: Circulation: Cardiovascular Imaging - April 7, 2017 Category: Radiology Authors: Yu, C.-W., Lee, H.-J., Suh, J., Lee, N.-H., Park, S.-M., Park, T. K., Yang, J. H., Song, Y. B., Hahn, J.-Y., Choi, S. H., Gwon, H.-C., Lee, S.-H., Choe, Y. H., Kim, S. M., Choi, J.-H. Tags: Computerized Tomography (CT), Percutaneous Coronary Intervention Coronary Artery Disease Source Type: research

Dynamic Computed Tomography Myocardial Perfusion Imaging: Comparison of Clinical Analysis Methods for the Detection of Vessel-Specific Ischemia [Ischemic Heart Disease]
Conclusions— Endocardial perfusion parameters obtained by semiautomatic analysis of dynamic computed tomography myocardial perfusion imaging may permit robust discrimination between coronary vessels causing ischemia versus not causing ischemia. (Source: Circulation: Cardiovascular Imaging)
Source: Circulation: Cardiovascular Imaging - April 7, 2017 Category: Radiology Authors: Rossi, A., Wragg, A., Klotz, E., Pirro, F., Moon, J. C., Nieman, K., Pugliese, F. Tags: Computerized Tomography (CT), Diagnostic Testing, Imaging Ischemic Heart Disease Source Type: research

18F-Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography in Cardiac Implantable Electronic Devices Infection: Ready for Routine Care! [Editorials]
(Source: Circulation: Cardiovascular Imaging)
Source: Circulation: Cardiovascular Imaging - April 4, 2017 Category: Radiology Authors: Rouzet, F., Le Guludec, D. Tags: Infectious Endocarditis, Nuclear Cardiology and PET Editorials Source Type: research

Positron Emission Tomography and Single-Photon Emission Computed Tomography Imaging in the Diagnosis of Cardiac Implantable Electronic Device Infection: A Systematic Review and Meta-Analysis [Molecular Imaging]
Conclusions— Both 18F-FDG PET-CT and LS yield high sensitivity, specificity, and accuracy, and thus seem to be useful for the diagnosis of CIED infection, based on robust data for 18F-FDG PET-CT but limited data for LS. When available,18F-FDG PET-CT may be preferred. (Source: Circulation: Cardiovascular Imaging)
Source: Circulation: Cardiovascular Imaging - April 4, 2017 Category: Radiology Authors: Juneau, D., Golfam, M., Hazra, S., Zuckier, L. S., Garas, S., Redpath, C., Bernick, J., Leung, E., Chih, S., Wells, G., Beanlands, R. S. B., Chow, B. J. W. Tags: Diagnostic Testing, Nuclear Cardiology and PET Molecular Imaging Source Type: research

Safety With Echocardiographic Contrast Agents [Advances in Cardiovascular Imaging]
In October 2007, the Food and Drug Administration mandated significant revisions to product labeling for the commercially available echocardiographic contrast agents (ECA) Definity and Optison after spontaneous healthcare provider reports of 4 patient deaths and 190 severe cardiopulmonary reactions occurring in close temporal relationship to ECA administration. Since then, multiple large ECA safety studies have been published and have included outpatients, hospitalized patients (including the critically ill), patients undergoing stress echocardiography, and patients with pulmonary hypertension. In addition, the Food and Dr...
Source: Circulation: Cardiovascular Imaging - April 4, 2017 Category: Radiology Authors: Muskula, P. R., Main, M. L. Tags: Echocardiography, Ultrasound Advances in Cardiovascular Imaging Source Type: research

Pulmonary Vascular Function During Exercise: Progressing Toward Routine Clinical Use [Editorial]
(Source: Circulation: Cardiovascular Imaging)
Source: Circulation: Cardiovascular Imaging - March 30, 2017 Category: Radiology Authors: Claessen, G., La Gerche, A. Tags: Pulmonary Hypertension, Echocardiography, Exercise Testing, Imaging Editorial Source Type: research

Changing the Paradigm in Type B Acute Aortic Dissection: Combining Clinical and Imaging Markers of Risk [Editorial]
(Source: Circulation: Cardiovascular Imaging)
Source: Circulation: Cardiovascular Imaging - March 30, 2017 Category: Radiology Authors: LaBounty, T. M., Eagle, K. A. Tags: Aortic Dissection Editorial Source Type: research