Coronary Artery Calcium and Risk of Dementia in MESA (Multi-Ethnic Study of Atherosclerosis) [Epidemiology]

Conclusions—
Higher baseline CAC was significantly associated with increased risk of dementia independent of vascular risk factor, APOE-4, and incident stroke. This is consistent with a hypothesis that vascular injuries play a role in the development of dementia.

Source: Circulation: Cardiovascular Imaging - May 2, 2017 Category: Radiology Authors: Fujiyoshi, A., Jacobs, D. R., Fitzpatrick, A. L., Alonso, A., Duprez, D. A., Sharrett, A. R., Seeman, T., Blaha, M. J., Luchsinger, J. A., Rapp, S. R. Tags: Epidemiology Source Type: research