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Employing Extracellular Volume Cardiovascular Magnetic Resonance Measures of Myocardial Fibrosis to Foster Novel Therapeutics [Advances in Cardiovascular Imaging]
Quantifying myocardial fibrosis (MF) with myocardial extracellular volume measures acquired during cardiovascular magnetic resonance promises to transform clinical care by advancing pathophysiologic understanding and fostering novel therapeutics. Extracellular volume quantifies MF by measuring the extracellular compartment depicted by the myocardial uptake of contrast relative to plasma. MF is a key domain of dysfunctional but viable myocardium among others (eg, microvascular dysfunction and cardiomyocyte/mitochondrial dysfunction). Although anatomically distinct, these domains may functionally interact. MF represents path...
Source: Circulation: Cardiovascular Imaging - May 16, 2017 Category: Radiology Authors: Schelbert, E. B., Sabbah, H. N., Butler, J., Gheorghiade, M. Tags: Heart Failure, Hypertrophy, Remodeling, Magnetic Resonance Imaging (MRI), Treatment Advances in Cardiovascular Imaging Source Type: research

Congenital Heart Disease: Multimodal Imaging Is Every Days Routine [Editor's Note]
(Source: Circulation: Cardiovascular Imaging)
Source: Circulation: Cardiovascular Imaging - May 11, 2017 Category: Radiology Authors: Beerbaum, P. B. J. Tags: Imaging Editor ' s Note Source Type: research

How to Image the Dilated Right Ventricle [How to Use Imaging]
(Source: Circulation: Cardiovascular Imaging)
Source: Circulation: Cardiovascular Imaging - May 11, 2017 Category: Radiology Authors: Partington, S. L., Kilner, P. J. Tags: Congenital Heart Disease, Myocardial Infarction, Valvular Heart Disease, Echocardiography, Magnetic Resonance Imaging (MRI) How to Use Imaging Source Type: research

How to Image the Adult Patient With Fontan Circulation [How to Use Imaging]
(Source: Circulation: Cardiovascular Imaging)
Source: Circulation: Cardiovascular Imaging - May 11, 2017 Category: Radiology Authors: Hauser, J. A., Taylor, A. M., Pandya, B. Tags: Computerized Tomography (CT), Diagnostic Testing, Echocardiography, Imaging, Magnetic Resonance Imaging (MRI) How to Use Imaging Source Type: research

How to Image Congenital Left Heart Obstruction in Adults [How to Use Imaging]
(Source: Circulation: Cardiovascular Imaging)
Source: Circulation: Cardiovascular Imaging - May 11, 2017 Category: Radiology Authors: Krieger, E. V., Stout, K. K., Grosse-Wortmann, L. Tags: Congenital Heart Disease, Computerized Tomography (CT), Echocardiography, Imaging, Magnetic Resonance Imaging (MRI) How to Use Imaging Source Type: research

How to Image Repaired Tetralogy of Fallot [How to Use Imaging]
(Source: Circulation: Cardiovascular Imaging)
Source: Circulation: Cardiovascular Imaging - May 11, 2017 Category: Radiology Authors: Valente, A. M., Geva, T. Tags: Congenital Heart Disease, Computerized Tomography (CT), Echocardiography, Electrocardiology (ECG), Magnetic Resonance Imaging (MRI) How to Use Imaging Source Type: research

Calcium Imaging in the Emergency Department: Between a Rock and a Hard Place [Editorial]
(Source: Circulation: Cardiovascular Imaging)
Source: Circulation: Cardiovascular Imaging - May 9, 2017 Category: Radiology Authors: Nieman, K. Tags: Computerized Tomography (CT) Editorial Source Type: research

Intraplaque and Cellular Distribution of Dextran-Coated Iron Oxide Fluorescently Labeled Nanoparticles: Insights Into Atherothrombosis and Plaque Rupture [Editorial]
(Source: Circulation: Cardiovascular Imaging)
Source: Circulation: Cardiovascular Imaging - May 9, 2017 Category: Radiology Authors: Calcagno, C., Fayad, Z. A. Tags: Atherosclerosis, Coronary Artery Disease, Thrombosis, Vascular Disease Editorial Source Type: research

Multitarget Vulnerable Plaque Imaging [Editorial]
(Source: Circulation: Cardiovascular Imaging)
Source: Circulation: Cardiovascular Imaging - May 9, 2017 Category: Radiology Authors: Dweck, M. R., Fayad, Z. A. Tags: Nuclear Cardiology and PET, Ultrasound, Atherosclerosis Editorial Source Type: research

Round Valve in an Oval Hole: Right-Sizing Prosthetic Aortic Valves With Preoperative Computed Tomography [Editorial]
(Source: Circulation: Cardiovascular Imaging)
Source: Circulation: Cardiovascular Imaging - May 9, 2017 Category: Radiology Authors: Benton, S. M., Litwin, S. E. Tags: Computerized Tomography (CT), Prognosis, Aortic Valve Replacement/Transcatheter Aortic Valve Implantation Editorial Source Type: research

Aortic Valve Annular Sizing: Intraoperative Assessment Versus Preoperative Multidetector Computed Tomography [Valvular Heart Disease]
Conclusions— Preoperative MDCT measurements differ substantially from direct intraoperative assessment of the aortic annulus. Implanted surgical aortic valve replacement valves were smaller relative to MDCT-based sizing in 41% of patients, and the potential GOA was between 25% and 40.6% larger if patients had undergone transcatheter aortic valve replacement. (Source: Circulation: Cardiovascular Imaging)
Source: Circulation: Cardiovascular Imaging - May 9, 2017 Category: Radiology Authors: George, I., Guglielmetti, L. C., Bettinger, N., Moss, A., Wang, C., Kheysin, N., Hahn, R., Kodali, S., Leon, M., Bapat, V., Borger, M. A., Williams, M., Smith, C., Khalique, O. K. Tags: Computerized Tomography (CT), Imaging, Aortic Valve Replacement/Transcatheter Aortic Valve Implantation, Catheter-Based Coronary and Valvular Interventions Valvular Heart Disease Source Type: research

Rare Solitary Fibrous Tumor in the Pulmonary Artery Mimicking Pulmonary Embolism [Cardiovascular Images]
(Source: Circulation: Cardiovascular Imaging)
Source: Circulation: Cardiovascular Imaging - May 9, 2017 Category: Radiology Authors: Luo, R., Xu, H., Zhang, P., Ye, F., Wang, F. Tags: Imaging, Nuclear Cardiology and PET, Embolism, Thrombosis, Vascular Disease Cardiovascular Images Source Type: research

Impact of Coronary Calcification on Clinical Management in Patients With Acute Chest Pain [Coronary Artery Disease]
Conclusions— Downstream testing, total, and diagnostic cost increased with increasing CAC, but were found to be appropriate because obstructive coronary artery disease and ACS were more prevalent in patients with high CAC. In patients with acute chest pain undergoing coronary CTA, cost-efficient testing and excellent diagnostic yield can be achieved even with high CAC burden. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifiers: NCT01084239 and NCT00933400. (Source: Circulation: Cardiovascular Imaging)
Source: Circulation: Cardiovascular Imaging - May 9, 2017 Category: Radiology Authors: Bittner, D. O., Mayrhofer, T., Bamberg, F., Hallett, T. R., Janjua, S., Addison, D., Nagurney, J. T., Udelson, J. E., Lu, M. T., Truong, Q. A., Woodard, P. K., Hollander, J. E., Miller, C., Chang, A. M., Singh, H., Litt, H., Hoffmann, U., Ferencik, M. Tags: Computerized Tomography (CT), Cost-Effectiveness, Acute Coronary Syndromes, Coronary Artery Disease Source Type: research

Head-to-Head Comparison of Inflammation and Neovascularization in Human Carotid Plaques: Implications for the Imaging of Vulnerable Plaques [Molecular Imaging]
Conclusions— Inflammation and intraplaque neovascularization are not systematically associated in carotid plaques, suggesting a temporal separation between the 2 processes. Inflammation seems more pronounced when symptoms are present. These data highlight the challenges that face any imaging strategy designed to assess plaque vulnerability. (Source: Circulation: Cardiovascular Imaging)
Source: Circulation: Cardiovascular Imaging - May 9, 2017 Category: Radiology Authors: Demeure, F., Bouzin, C., Roelants, V., Bol, A., Verhelst, R., Astarci, P., Gerber, B. L., Pouleur, A.-C., Pasquet, A., de Meester, C., Vanoverschelde, J.-L. J., Vancraeynest, D. Tags: Pathophysiology, Imaging, Nuclear Cardiology and PET, Ultrasound, Atherosclerosis Molecular Imaging Source Type: research

Atheroma Susceptible to Thrombosis Exhibit Impaired Endothelial Permeability In Vivo as Assessed by Nanoparticle-Based Fluorescence Molecular Imaging [Molecular Imaging]
Conclusions— Plaques that exhibit impaired in vivo endothelial permeability in cell-rich areas are susceptible to subsequent thrombosis. Molecular imaging of nanoparticle deposition may help to identify biologically high-risk atheroma. (Source: Circulation: Cardiovascular Imaging)
Source: Circulation: Cardiovascular Imaging - May 9, 2017 Category: Radiology Authors: Stein-Merlob, A. F., Hara, T., McCarthy, J. R., Mauskapf, A., Hamilton, J. A., Ntziachristos, V., Libby, P., Jaffer, F. A. Tags: Endothelium/Vascular Type/Nitric Oxide, Translational Studies, Imaging, Atherosclerosis, Thrombosis Molecular Imaging Source Type: research