Atheroma Susceptible to Thrombosis Exhibit Impaired Endothelial Permeability In Vivo as Assessed by Nanoparticle-Based Fluorescence Molecular Imaging [Molecular Imaging]

Conclusions—
Plaques that exhibit impaired in vivo endothelial permeability in cell-rich areas are susceptible to subsequent thrombosis. Molecular imaging of nanoparticle deposition may help to identify biologically high-risk atheroma.

Source: Circulation: Cardiovascular Imaging - May 9, 2017 Category: Radiology Authors: Stein-Merlob, A. F., Hara, T., McCarthy, J. R., Mauskapf, A., Hamilton, J. A., Ntziachristos, V., Libby, P., Jaffer, F. A. Tags: Endothelium/Vascular Type/Nitric Oxide, Translational Studies, Imaging, Atherosclerosis, Thrombosis Molecular Imaging Source Type: research