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Response by Feola et al to Letter Regarding Article, "Localized Optogenetic Targeting of Rotors in Atrial Cardiomyocyte Monolayers" [Letter to the Editor]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - February 8, 2018 Category: Cardiology Authors: Feola, I., Volkers, L., Majumder, R., Teplenin, A., Schalij, M. J., Panfilov, A. V., de Vries, A. A. F., Pijnappels, D. A. Tags: Electrophysiology, Atrial Fibrillation, Basic Science Research Letter to the Editor Source Type: research

Letter by Houston et al Regarding Article, "Localized Optogenetic Targeting of Rotors in Atrial Cardiomyocyte Monolayers" [Letter to the Editor]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - February 8, 2018 Category: Cardiology Authors: Houston, C., Ng, F. S., Dupont, E. Tags: Arrhythmias, Cell Biology/Structural Biology, Mechanisms Letter to the Editor Source Type: research

Right Ventricular Outflow Tract Electroanatomical Abnormalities Predict Ventricular Fibrillation Inducibility in Brugada Syndrome [Research Letter]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - February 8, 2018 Category: Cardiology Authors: Letsas, K. P., Efremidis, M., Asvestas, D., Vlachos, K., Georgopoulos, S., Tse, G., Liu, T., Bazoukis, G., Sideris, A., Baranchuk, A., Ehrlich, J. R., Brugada, P. Tags: Electrophysiology, Sudden Cardiac Death, Ventricular Fibrillation Research Letter Source Type: research

Altered Repolarization Reserve in Failing Rabbit Ventricular Myocytes: Calcium and {beta}-Adrenergic Effects on Delayed- and Inward-Rectifier Potassium Currents [Original Articles]
Conclusions: At baseline Ca2+-dependent upregulation of IKr and IKs in HF counterbalances the reduced IK1, maintaining repolarization reserve (especially at higher heart rates) in physiological conditions, unlike conditions of strong cytosolic Ca2+ buffering. However, under β-adrenergic stimulation, reduced IKs responsiveness severely limits integrated repolarizing K+ current and repolarization reserve in HF. This would increase arrhythmia propensity in HF, especially during adrenergic stress. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - February 8, 2018 Category: Cardiology Authors: Hegyi, B., Bossuyt, J., Ginsburg, K. S., Mendoza, L. M., Talken, L., Ferrier, W. T., Pogwizd, S. M., Izu, L. T., Chen-Izu, Y., Bers, D. M. Tags: Electrophysiology, Ion Channels/Membrane Transport, Heart Failure Original Articles Source Type: research

Transvenous Lead Extraction in Adults With Congenital Heart Disease: Insights From a 20-Year Single-Center Experience [Original Articles]
Conclusions: Despite complex anatomic issues, TLE can be achieved successfully in most A-CHD using advanced extraction techniques. Subpulmonary atrioventricular valve regurgitation is a prevalent complication, particularly in patients with transposition of the great arteries. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - February 8, 2018 Category: Cardiology Authors: Gourraud, J.-B., Chaix, M.-A., Shohoudi, A., Page, P., Dubuc, M., Thibault, B., Poirier, N. C., Dore, A., Marcotte, F., Mongeon, F.-P., Asgar, A. W., Ibrahim, R., Khairy, P., Mondesert, B. Tags: Catheter Ablation and Implantable Cardioverter-Defibrillator, Congenital Heart Disease, Pacemaker Original Articles Source Type: research

February 5th Question [Challenge of the Week]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - February 5, 2018 Category: Cardiology Authors: Noheria, A. Tags: Catheter Ablation and Implantable Cardioverter-Defibrillator Challenge of the Week Source Type: research

Long-Term Clinical Comparison of Procedural End Points After Pulmonary Vein Isolation in Paroxysmal Atrial Fibrillation: Elimination of Nonpulmonary Vein Triggers Versus Noninducibility [Original Articles]
Conclusions: Elimination of triggers as an end point of ablation in patients with paroxysmal atrial fibrillation decreased long-term recurrence of atrial tachyarrhythmia compared with a noninducibility approach achieved by additional empirical ablation. The post-PVI trigger test is thus a better end point of ablation for paroxysmal atrial fibrillation. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - February 5, 2018 Category: Cardiology Authors: Lee, K.-N., Roh, S.-Y., Baek, Y.-S., Park, H.-S., Ahn, J., Kim, D.-H., Lee, D. I., Shim, J., Choi, J.-I., Park, S.-W., Kim, Y.-H. Tags: Arrhythmias, Electrophysiology, Atrial Fibrillation Original Articles Source Type: research

January 29th Question [Challenge of the Week]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - January 29, 2018 Category: Cardiology Authors: Noheria, A. Tags: Challenge of the Week Source Type: research

January 22nd Question [Challenge of the Week]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - January 22, 2018 Category: Cardiology Authors: Noheria, A. Tags: Challenge of the Week Source Type: research

In This Issue: January [In This Issue: January]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - January 16, 2018 Category: Cardiology Tags: In This Issue: January Source Type: research

Circulation: Arrhythmia and Electrophysiology Editors and Editorial Board [Circulation: Arrhythmia and Electrophysiology Masthead]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - January 16, 2018 Category: Cardiology Tags: Circulation: Arrhythmia and Electrophysiology Masthead Source Type: research

January 15th Question [Challenge of the Week]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - January 15, 2018 Category: Cardiology Authors: Noheria, A. Tags: Electrocardiology (ECG), Pacemaker Challenge of the Week Source Type: research

Standard Ablation Versus Magnetic Resonance Imaging-Guided Ablation in the Treatment of Ventricular Tachycardia [Research Letter]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - January 12, 2018 Category: Cardiology Authors: Zghaib, T., Ipek, E. G., Hansford, R., Ashikaga, H., Berger, R. D., Marine, J. E., Spragg, D. D., Tandri, H., Zimmerman, S. L., Halperin, H., Brancato, S., Calkins, H., Henrikson, C., Nazarian, S. Tags: Arrhythmias, Electrophysiology, Ventricular Fibrillation, Imaging, Magnetic Resonance Imaging (MRI) Research Letter Source Type: research

Identification and Characterization of Sites Where Persistent Atrial Fibrillation Is Terminated by Localized Ablation [Original Articles]
Conclusions: Local activation mapping at sites of termination of persistent AF showed repetitive patterns of rotational or focal activity. In computer simulations, complete rotational activation sequence was observed but was sensitive to assignment of activation timing particularly in segments of slow conduction. The observed phenomena of repetitive localized activation and the mechanism by which local ablation terminates putative AF drivers require further investigation. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - January 12, 2018 Category: Cardiology Authors: Zaman, J. A. B., Sauer, W. H., Alhusseini, M. I., Baykaner, T., Borne, R. T., Kowalewski, C. A. B., Busch, S., Zei, P. C., Park, S., Viswanathan, M. N., Wang, P. J., Brachmann, J., Krummen, D. E., Miller, J. M., Rappel, W. J., Narayan, S. M., Peters, N. S Tags: Arrhythmias, Catheter Ablation and Implantable Cardioverter-Defibrillator, Electrophysiology, Atrial Fibrillation Original Articles Source Type: research

Ventricular Arrhythmias Linked to the Left Ventricular Summit Communicating Veins: A New Mapping Approach for an Old Ablation Problem [Editorial]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - January 11, 2018 Category: Cardiology Authors: Muser, D., Santangeli, P. Tags: Arrhythmias, Catheter Ablation and Implantable Cardioverter-Defibrillator Editorial Source Type: research