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Optimizing Antitachycardia Pacing: Back to the Roots [Editorials]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - September 8, 2017 Category: Cardiology Authors: Duncker, D., Veltmann, C. Tags: Catheter Ablation and Implantable Cardioverter-Defibrillator Editorials Source Type: research

Rotors: How Do We Know When They Are Real? [Editorials]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - September 8, 2017 Category: Cardiology Authors: Aronis, K. N., Berger, R. D., Ashikaga, H. Tags: Arrhythmias, Electrophysiology, Computational Biology Editorials Source Type: research

Resolving Bipolar Electrogram Voltages During Atrial Fibrillation Using Omnipolar Mapping [Original Articles]
Conclusions: Omnipolar EGMs can extract maximal voltages from AF signals which are not influenced by directional factors, collision or fractionation, compared with contemporary bipolar techniques. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - September 8, 2017 Category: Cardiology Authors: Haldar, S. K., Magtibay, K., Porta-Sanchez, A., Masse, S., Mitsakakis, N., Lai, P. F. H., Azam, M. A., Asta, J., Kusha, M., Dorian, P., Ha, A. C. T., Chauhan, V., Deno, D. C., Nanthakumar, K. Tags: Arrhythmias, Catheter Ablation and Implantable Cardioverter-Defibrillator, Electrophysiology Original Articles Source Type: research

Technical Considerations on Phase Mapping for Identification of Atrial Reentrant Activity in Direct- and Inverse-Computed Electrograms [Original Articles]
Conclusions: Rotor identification is accurate and sensitive and does not require additional signal processing in measured or noninvasively computed unipolar EGMs. Bipolar EGMs and body surface potential mapping do require HDF filtering to detect rotors at the expense of a decreased specificity. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - September 8, 2017 Category: Cardiology Authors: Rodrigo, M., Climent, A. M., Liberos, A., Fernandez-Aviles, F., Berenfeld, O., Atienza, F., Guillem, M. S. Tags: Catheter Ablation and Implantable Cardioverter-Defibrillator, Electrophysiology, Electrocardiology (ECG), Imaging Original Articles Source Type: research

Initial Clinical Experience With a New Automated Antitachycardia Pacing Algorithm: Feasibility and Safety in an Ambulatory Patient Cohort [Original Articles]
Conclusions: The new AATP algorithm safely generated ATP sequences and controlled therapy progression in all zones without need for individualized programing. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - September 8, 2017 Category: Cardiology Authors: Yee, R., Fisher, J. D., Birgersdotter-Green, U., Smith, T. W., Kenigsberg, D. N., Canby, R., Jackson, T., Taepke, R., DeGroot, P. Tags: Catheter Ablation and Implantable Cardioverter-Defibrillator, Electrophysiology, Sudden Cardiac Death Original Articles Source Type: research

Primum Non Nocere: The Paramount Importance of Esophageal Protection [Editorial]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - August 10, 2017 Category: Cardiology Authors: Koneru, J. N., Kaszala, K., Ellenbogen, K. A. Tags: Catheter Ablation and Implantable Cardioverter-Defibrillator, Atrial Fibrillation Editorial Source Type: research

Cancer Treatment-Induced Arrhythmias: Focus on Chemotherapy and Targeted Therapies [Advances in Arrhythmia and Electrophysiology]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - August 10, 2017 Category: Cardiology Authors: Buza, V., Rajagopalan, B., Curtis, A. B. Tags: Arrhythmias Advances in Arrhythmia and Electrophysiology Source Type: research

Progression From Esophageal Thermal Asymptomatic Lesion to Perforation Complicating Atrial Fibrillation Ablation: A Single-Center Registry [Original Articles]
Conclusions— Postablation endoscopy seems to identify patients at high risk of esophageal perforating complications only occurring in patients with category 2 EDEL. One out of 10 postablation esophageal ulcers progressed to perforation, and no patient without esophageal thermal ulcers showed the occurrence of perforating esophageal complications. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - August 10, 2017 Category: Cardiology Authors: Halbfass, P., Pavlov, B., Muller, P., Nentwich, K., Sonne, K., Barth, S., Hamm, K., Fochler, F., Mugge, A., Lusebrink, U., Kuhn, R., Deneke, T. Tags: Arrhythmias, Catheter Ablation and Implantable Cardioverter-Defibrillator, Atrial Fibrillation Original Articles Source Type: research

Unipolar Endocardial Voltage Mapping in the Right Ventricle: Optimal Cutoff Values Correcting for Computed Tomography-Derived Epicardial Fat Thickness and Their Clinical Value for Substrate Delineation [Original Article]
Conclusions— For identification of epicardial right ventricular scar, an endocardial UV cutoff value of 3.9 mV is more accurate than previously reported cutoff values. Although the majority of epicardial abnormal electrograms are associated with transmural scar with low endocardial BV, the additional use of endocardial UV at normal BV sites improves the diagnostic accuracy resulting in identification of all epicardial abnormal electrograms at sites with <1.0 mm fat. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - August 10, 2017 Category: Cardiology Authors: Venlet, J., Piers, S. R. D., Kapel, G. F. L., de Riva, M., Pauli, P. F. G., van der Geest, R. J., Zeppenfeld, K. Tags: Arrhythmias, Catheter Ablation and Implantable Cardioverter-Defibrillator, Electrophysiology, Computerized Tomography (CT) Original Article Source Type: research

Response by Rivarola and Scanavacca to Letter Regarding Article, "Targets and End Points in Cardiac Autonomic Denervation Procedures" [Correspondence]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - August 9, 2017 Category: Cardiology Authors: Rivarola, E., Scanavacca, M. Tags: Arrhythmias, Catheter Ablation and Implantable Cardioverter-Defibrillator, Electrophysiology, Pacemaker, Neurostimulation Correspondence Source Type: research

Loss-of-Function KCNE2 Variants: True Monogenic Culprits of Long-QT Syndrome or Proarrhythmic Variants Requiring Secondary Provocation? [Original Articles]
Conclusions— On the basis of clinical phenotype, the high allelic frequencies of LQT6 mutations in the Exome Aggregation Consortium database, and absence of previous documentation of genotype–phenotype segregation, our findings suggest that many KCNE2 variants, and perhaps all, have been erroneously designated as LQTS-causative mutations. Instead, KCNE2 variants may confer proarrhythmic susceptibility when provoked by additional environmental/acquired or genetic factors, or both. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - August 9, 2017 Category: Cardiology Authors: Roberts, J. D., Krahn, A. D., Ackerman, M. J., Rohatgi, R. K., Moss, A. J., Nazer, B., Tadros, R., Gerull, B., Sanatani, S., Wijeyeratne, Y. D., Baruteau, A.-E., Muir, A. R., Pang, B., Cadrin-Tourigny, J., Talajic, M., Rivard, L., Tester, D. J., Liu, T., Tags: Arrhythmias, Sudden Cardiac Death, Genetics Original Articles Source Type: research

Letter by Debruyne Regarding Article, "Targets and End Points in Cardiac Autonomic Denervation Procedures" [Correspondence]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - August 9, 2017 Category: Cardiology Authors: Debruyne, P. Tags: Catheter Ablation and Implantable Cardioverter-Defibrillator, Electrophysiology, Autonomic Nervous System, Electrocardiology (ECG), Treatment Correspondence Source Type: research

Idiopathic Ventricular Arrhythmias Originating From the Parietal Band: Electrocardiographic and Electrophysiological Characteristics and Outcome of Catheter Ablation [Original Articles]
Conclusions— Idiopathic VAs rarely originated from the parietal band. The catheter ablation of the parietal band VAs was always challenging, requiring a large amount of the radiofrequency energy delivery for a successful ablation with a relatively high recurrence rate. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - August 9, 2017 Category: Cardiology Authors: Yamada, T., Yoshida, N., Itoh, T., Litovsky, S. H., Doppalapudi, H., McElderry, H. T., Kay, G. N. Tags: Catheter Ablation and Implantable Cardioverter-Defibrillator Original Articles Source Type: research

Mechanically Induced Ectopy via Stretch-Activated Cation-Nonselective Channels Is Caused by Local Tissue Deformation and Results in Ventricular Fibrillation if Triggered on the Repolarization Wave Edge (Commotio Cordis) [Original Articles]
Conclusions— Local mechanical tissue deformation determines PVEM induction via stretch-activation of cation-nonselective channels, with VF induction requiring PVEM overlap with the trailing edge of a normal repolarization wave. This defines a narrow, subject-specific vulnerable window for commotio cordis–induced VF that exists both in time and in space. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - August 9, 2017 Category: Cardiology Authors: Quinn, T. A., Jin, H., Lee, P., Kohl, P. Tags: Arrhythmias, Electrophysiology, Sudden Cardiac Death, Ventricular Fibrillation, Mechanisms Original Articles Source Type: research

First-in-Man Analysis of the Relationship Between Electrical Rotors From Noninvasive Panoramic Mapping and Atrial Fibrosis From Magnetic Resonance Imaging in Patients With Persistent Atrial Fibrillation [Original Articles]
Conclusions— This is the first study demonstrating that the presence of rotors based on NEEES analysis is not directly associated with the extent and anatomic location of LGE signal intensity from CMR. Further studies evaluating the relationship between rotors and fibrosis in patients with persistent atrial fibrillation are mandatory and may inform strategies to improve ablation outcome. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - August 8, 2017 Category: Cardiology Authors: Sohns, C., Lemes, C., Metzner, A., Fink, T., Chmelevsky, M., Maurer, T., Budanova, M., Solntsev, V., Schulze, W. H. W., Staab, W., Mathew, S., Heeger, C., Reissmann, B., Kholmovski, E., Kivelitz, D., Ouyang, F., Kuck, K.-H. Tags: Catheter Ablation and Implantable Cardioverter-Defibrillator, Atrial Fibrillation, Magnetic Resonance Imaging (MRI) Original Articles Source Type: research