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Inducibility Conundrum for Ablation of Ventricular Tachycardia: Are We Done Yet? [Editorial]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - March 15, 2018 Category: Cardiology Authors: John, R. M., Kanagasundram, A. N., Stevenson, W. G. Tags: Arrhythmias, Catheter Ablation and Implantable Cardioverter-Defibrillator, Quality and Outcomes Editorial Source Type: research

What We Know, What We Think We Know, and What We Do Not Know at All: The Contemporary Conundrum of Secondary-Prevention Implantable Cardioverter Defibrillator Therapy [Editorial]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - March 15, 2018 Category: Cardiology Authors: Patton, K. K., Poole, J. E. Tags: Arrhythmias, Catheter Ablation and Implantable Cardioverter-Defibrillator, Sudden Cardiac Death, Ventricular Fibrillation Editorial Source Type: research

Beyond Pulmonary Vein Isolation for Persistent Atrial Fibrillation: Dont Just Do Something, Stand There [Editorial]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - March 15, 2018 Category: Cardiology Authors: Frankel, D. S., Dixit, S. Tags: Catheter Ablation and Implantable Cardioverter-Defibrillator, Atrial Fibrillation Editorial Source Type: research

Implantable Defibrillator Therapy in Cardiac Arrest Survivors With a Reversible Cause [Original Articles]
Conclusions: In survivors of SCA because of a reversible and correctable cause, ICD therapy is associated with lower all-cause mortality except if the SCA was because of myocardial infarction. These data deserve further investigation in a prospective multicenter randomized controlled trial, as they may have important and immediate clinical implications. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - March 15, 2018 Category: Cardiology Authors: Ladejobi, A., Pasupula, D. K., Adhikari, S., Javed, A., Durrani, A. F., Patil, S., Qin, D., Ahmad, S., Munir, M. B., Rijal, S., Wayne, M., Adelstein, E., Jain, S., Saba, S. Tags: Sudden Cardiac Death Original Articles Source Type: research

Long-Term Outcome of Pulmonary Vein Isolation With and Without Focal Impulse and Rotor Modulation Mapping: Insights From a Meta-Analysis [Original Articles]
Conclusions: The overall pooled estimate did not show any therapeutic benefit of PVI+FIRM approach over PVI alone, which suggests the need to reevaluate the clinical use of FIRM ablation in atrial fibrillation. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - March 15, 2018 Category: Cardiology Authors: Mohanty, S., Mohanty, P., Trivedi, C., Gianni, C., Della Rocca, D. G., Di Biase, L., Natale, A. Tags: Atrial Fibrillation Original Articles Source Type: research

Defining the Outcome of Ventricular Tachycardia Ablation: Timing and Value of Programmed Ventricular Stimulation [Original Articles]
Conclusions: PVS at day 6 predicts VT recurrence more accurately allowing to identify patients who might benefit from a redo ablation and addressing implantable cardioverter defibrillator programming. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - March 15, 2018 Category: Cardiology Authors: Oloriz, T., Baratto, F., Trevisi, N., Barbaro, M., Bisceglia, C., DAngelo, G., Yamase, M., Paglino, G., Radinovic, A., Della Bella, P. Tags: Arrhythmias, Catheter Ablation and Implantable Cardioverter-Defibrillator, Electrophysiology, Ventricular Fibrillation Original Articles Source Type: research

Electrocardiographic Repolarization Abnormalities and Electroanatomic Substrate in Arrhythmogenic Right Ventricular Cardiomyopathy [Original Articles]
Conclusions: In arrhythmogenic RV cardiomyopathy, abnormal electroanatomic mapping areas are proportional to extent of T-wave inversion on 12-lead ECG. Marked voltage abnormalities can exist without repolarization change. Downsloping elevated ST-segment pattern in V1 and V2 occurs with more unipolar endocardial voltage abnormality, consistent with more advanced transmural disease. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - March 15, 2018 Category: Cardiology Authors: Kubala, M., Pathak, R. K., Xie, S., Casado Arroyo, R., Tschabrunn, C. M., Hayashi, T., Garcia, F. C., Supple, G. E., Santangeli, P., Frankel, D. S., Zado, E. S., Callans, D. J., Marchlinski, F. E. Tags: Arrhythmias, Catheter Ablation and Implantable Cardioverter-Defibrillator, Electrophysiology, Cardiomyopathy, Electrocardiology (ECG) Original Articles Source Type: research

Left Septal Slow Pathway Ablation for Atrioventricular Nodal Reentrant Tachycardia [Original Articles]
Conclusions: Left septal ablation at the anatomic site of the left inferior nodal extension is an alternative for ablation of both typical and atypical AVNRT when ablation at the right posterior septum is ineffective. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - March 14, 2018 Category: Cardiology Authors: Katritsis, D. G., John, R. M., Latchamsetty, R., Muthalaly, R. G., Zografos, T., Katritsis, G. D., Stevenson, W. G., Efimov, I. R., Morady, F. Tags: Arrhythmias, Catheter Ablation and Implantable Cardioverter-Defibrillator, Electrophysiology Original Articles Source Type: research

Atrial Infarction-Induced Spontaneous Focal Discharges and Atrial Fibrillation in Sheep: Role of Dantrolene-Sensitive Aberrant Ryanodine Receptor Calcium Release [Original Articles]
Conclusions: Atrial ischemia causes spontaneous AF episodes in sheep, caused by SFDs that initiate reentry. Nitroso–redox imbalance in the ischemic zone is associated with intense reactive oxygen species production and altered RyR2 responses to CaM. Dantrolene administration normalizes the CaM response, prevents LAMI-related SFDs, and AF initiation. These findings provide novel insights into the mechanisms underlying ischemia-related atrial arrhythmias. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - March 14, 2018 Category: Cardiology Authors: Avula, U. M. R., Hernandez, J. J., Yamazaki, M., Valdivia, C. R., Chu, A., Rojas-Pena, A., Kaur, K., Ramos-Mondragon, R., Anumonwo, J. M., Nattel, S., Valdivia, H. H., Kalifa, J. Tags: Electrophysiology, Atrial Fibrillation, Ischemia, Oxidant Stress Original Articles Source Type: research

Incidence and Clinical Significance of New-Onset Device-Detected Atrial Tachyarrhythmia: A Meta-Analysis [Original Articles]
Conclusions: New-onset DDAT is common, affecting close to one quarter of all patients with implanted pacemakers or defibrillators. Adjudication of atrial electrograms further identifies at-risk patients, even when relatively short detection thresholds are used. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - March 14, 2018 Category: Cardiology Authors: Belkin, M. N., Soria, C. E., Waldo, A. L., Borleffs, C. J. W., Hayes, D. L., Tung, R., Singh, J. P., Upadhyay, G. A. Tags: Arrhythmias, Catheter Ablation and Implantable Cardioverter-Defibrillator, Electrophysiology, Atrial Fibrillation, Pacemaker, Cerebrovascular Disease/Stroke Original Articles Source Type: research

Clinical Outcome of Electrophysiologically Guided Ablation for Nonparoxysmal Atrial Fibrillation Using a Novel Real-Time 3-Dimensional Mapping Technique: Results From a Prospective Randomized Trial [Original Articles]
Conclusions: Targeted ablation of regions showing RRa provided an adjunctive benefit in terms of arrhythmia freedom at 1-year follow-up in the treatment of persistent AF. These findings might support a patient-tailored strategy in subjects with nonparoxysmal AF and should be confirmed by additional larger, randomized, multicenter studies. Clinical Trial Registration: URL: https://www.clinicaltrials.gov. Unique identifier NCT02571218. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - March 13, 2018 Category: Cardiology Authors: Pappone, C., Ciconte, G., Vicedomini, G., Mangual, J. O., Li, W., Conti, M., Giannelli, L., Lipartiti, F., McSpadden, L., Ryu, K., Guazzi, M., Menicanti, L., Santinelli, V. Tags: Arrhythmias, Catheter Ablation and Implantable Cardioverter-Defibrillator, Electrophysiology, Atrial Fibrillation Original Articles Source Type: research

March 12th Question [Challenge of the Week]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - March 12, 2018 Category: Cardiology Authors: Noheria, A. Tags: Catheter Ablation and Implantable Cardioverter-Defibrillator Challenge of the Week Source Type: research

March 5th Question [Challenge of the Week]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - March 5, 2018 Category: Cardiology Authors: Noheria, A. Tags: Atrial Fibrillation Challenge of the Week Source Type: research

Global ECG Measures and Cardiac Structure and Function: The ARIC Study (Atherosclerosis Risk in Communities) [Original Articles]
Conclusions: GEH is a marker of subclinical abnormalities in cardiac structure and function. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - March 1, 2018 Category: Cardiology Authors: Biering-Sorensen, T., Kabir, M., Waks, J. W., Thomas, J., Post, W. S., Soliman, E. Z., Buxton, A. E., Shah, A. M., Solomon, S. D., Tereshchenko, L. G. Tags: Electrophysiology, Aging, Epidemiology, Echocardiography, Electrocardiology (ECG) Original Articles Source Type: research

February 26th Question [Challenge of the Week]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - February 26, 2018 Category: Cardiology Authors: Santangeli, P. Tags: Arrhythmias, Catheter Ablation and Implantable Cardioverter-Defibrillator, Electrophysiology Challenge of the Week Source Type: research