Rol genes enhance content of artemisinin and other secondary metabolites in Shennong hybrid of Artemisia annua
Conclusion: rolB and rolC genes were effective for developing A. annua plants with an enhanced level of phytochemicals. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - January 4, 2019 Category: Complementary Medicine Source Type: research
Traditional Chinese medicines treating macrophage: A particular strategy for atherosclerosis
Publication date: Available online 7 December 2018Source: Chinese Herbal MedicinesAuthor(s): Shan Lu, Yun Luo, Gui-bo Sun, Xiao-bo SunAbstractAtherosclerosis is a major cause of cardiovascular disease and one of the most deadly diseases in the world. Macrophages are the main contributors in the development of atherosclerosis, a target that drugs inhibit the inflammation and regulate lipid metabolism. In this review, we summarized the effects and mechanisms of traditional Chinese medicines and their bioactive compounds on atherosclerosis. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - December 8, 2018 Category: Complementary Medicine Source Type: research
Neuroprotective effect of Sanqi Tongshuan Tablets on sequelae post-stroke in rats
Conclusion: SQTS showed therapeutic benefits on sequelae post-stroke in rats, which might be through the pathway of regeneration or neuroplasticity. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - December 7, 2018 Category: Complementary Medicine Source Type: research
Typha angustifolia extract reduces diet-induced hyperlipidemia in rats
ConclusionThese results suggest that TAE is capable of effectively decreasing the circulating lipids levels and enhancing the protective effects of artery. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - December 7, 2018 Category: Complementary Medicine Source Type: research
Therapeutic effects of traditional Chinese herbal prescriptions for primary dysmenorrhea
Publication date: Available online 22 November 2018Source: Chinese Herbal MedicinesAuthor(s): Dorjbat Sosorburam, Zengguang Wu, Sichao Zhang, Peng Hu, Haiyan Zhang, Tong Jiang, Joshua Ahiasi-Mensah, Xin HeAbstractPrimary dysmenorrhea is a common disease among females in their reproductive age and adolescents. The main complaint is lower abdominal pain during menstruation. Females, who suffer from dysmenorrhea, widely use nonsteroidal anti-inflammatory drugs that reduce muscle spasm by inhibiting prostaglandin synthesis and vasopressin secretion. However, there are side effects when patients take them for a long time. It is...
Source: Chinese Herbal Medicines - November 23, 2018 Category: Complementary Medicine Source Type: research
Neuroprotective effect of Paeoniae Radix Rubra on hippocampal CA1 region of mice induced by transient focal cerebral ischemia via anti-gliosis and anti-oxidant activity
ConclusionPRR improved neuronal injuries that were induced by transient cerebral ischemia via inhibiting gliosis and elevating antioxidants. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - November 15, 2018 Category: Complementary Medicine Source Type: research
Synergistic interactions of catalpol and stachyose in STZ-HFD induced diabetic mice: synergism in regulation of blood glucose, lipids, and hepatic and renal function
ConclusionThus, we concluded that there were synergistic therapeutic effects between CAT and STA on STZ/HFD-induced type 2 diabetes. This project provided insights and technical supports for the innovation of discovering bioactive constituents in Rehmannia Radix and studying its integrative mechanism in curing diabetes. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - November 14, 2018 Category: Complementary Medicine Source Type: research
Potential mechanism of cholagogic effect about Gardenia Jasminoides Ellis (Zhizi)-mediated increase of bile acids urinary excretion in normal rats
ConclusionThe findings indicate that Zhizi reduces hepatic total BAs level by increasing urinary excretion rather than the biliary excretion of BAs, which, in turn ascribed to elevated protein expression of Mrp2 at apical membrane of renal tubular epithelial cells. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - November 2, 2018 Category: Complementary Medicine Source Type: research
Understanding ``medicine and food homology'', developing utilization in medicine functions
Publication date: October 2018Source: Chinese Herbal Medicines, Volume 10, Issue 4Author(s): Changxiao Liu (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - November 2, 2018 Category: Complementary Medicine Source Type: research
Neuroprotective effect of Paeoniae Radix Rubra on hippocampal CA1: region of mice induced by transient focal cerebral ischemia via anti-gliosis and anti-oxidant activity
Conclusion: PRR improved neuronal injuries that were induced by transient cerebral ischemia via inhibiting gliosis and elevating antioxidants. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - October 29, 2018 Category: Complementary Medicine Source Type: research
Anti-inflammatory activities of gentiopicroside against iNOS and COX-2 targets
ConclusionThese results suggested that the mechanism of anti-inflammatory activity of gentiopicroside was associated with the downregulation of inflammatory cytokines, such as NO, PGE2, and IL-6, and the suppression of iNOS and COX-2. Therefore, gentiopicroside is a potential and selective iNOS and COX-2 inhibitor. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - October 29, 2018 Category: Complementary Medicine Source Type: research
Monitoring unbound warfarin in drug combination therapy by pharmacokinetics and fluorospectrometry
ConclusionCombination therapy of DHI with warfarin could enhance the release profile of warfarin from serum protein. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - October 24, 2018 Category: Complementary Medicine Source Type: research
Positive effects of low dose IMPX977 on Rett syndrome related MeCP2 targeted-genes
ConclusionLow-dose treatment of IMPX977 (10 mg/kg) showed a positive effect on MeCP2 targeted-genes and it may serve as a drug candidate for Rett syndrome therapy with proper dosage. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - October 24, 2018 Category: Complementary Medicine Source Type: research
Pharmacokinetic and NMR metabolomics approach to evaluate therapeutic effect of berberine and Coptidis Rhizoma for sepsis
ConclusionBerberine exhibited an equivalent and even better therapeutic effect than Coptidis Rhizoma. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - October 18, 2018 Category: Complementary Medicine Source Type: research
Screening potential α-glucosidase inhibitors from Anemarrhena asphodeloides using response surface methodology coupled with grey relational analysis
ConclusionThe fraction eluted by 80% ethanol showed the best inhibitory activity. After analyzing the data of UPLC-Q-TOF-MS, 25 steroid saponins were tentatively identified in this fraction. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - October 14, 2018 Category: Complementary Medicine Source Type: research
