Research and application of Alpinia officinarum in medicinal field
In this study, we summarized the current knowledge about its botanical resources, ethanopharmacological function, chemical constituents, pharmacologies and pharmacokinetics, safety and toxicity, and clinical application. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - April 6, 2019 Category: Complementary Medicine Source Type: research

Metabolic profiling of icaritin in rats using UHPLC-Q/TOF-MS
ConclusionThe main metabolite types of icaritin in rats were glucuronide conjugation, methylation, hydroxylation, reduction, and acetylation. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - March 21, 2019 Category: Complementary Medicine Source Type: research

Discrimination of toxic ingredient between raw and processed Pinellia ternata by UPLC/Q-TOF-MS/MS with principal component analysis and T-test
ConclusionAn approach to explain the mechanisms of reducing the toxicity in medicinal plants by processing was proposed. Moreover, the chemical markers of toxicity could be used to differentiate the raw material from processed herbs for the quality control and safety application in clinical practice. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - March 21, 2019 Category: Complementary Medicine Source Type: research

Fumigant toxicity and sublethal effects of Teucrium polium essential oil on Aphis fabae scopoli A
ConclusionThe results of this study revealed that EO of T. polium could be used as a potential control agent for the aphid. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - March 14, 2019 Category: Complementary Medicine Source Type: research

Ginsenoside Rd improves behavioral impairment of rats with acute plateau status by modulating synaptic plasticity
ConclusionLow pressure and low oxygen environment of plateau damages the plasticity changes of the synaptic structure and function. And to a certain extent, ginsenoside Rd reverses Gray I synaptic interface structure parameters, so as to improve the behavior performance of model rats at high altitude condition. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - March 12, 2019 Category: Complementary Medicine Source Type: research

A guinea pig model of Ciwujia Injection-induced anaphylaxis for allergic substance screening
ConclusionThis guinea pig model may provide a powerful tool to study the mechanism in CWJI induced anaphylaxis and screen the allergic source of CWJI. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - March 10, 2019 Category: Complementary Medicine Source Type: research

Effects and mechanism of total phenols of Magnolia officinalis combined with Maijunan Tablets on blood pressure of spontaneous hypertensive rats
ConclusionThese results indicated that M-MJA could regulate the renin-angiotensin-aldosterone system, improve endothelial function, and inhibit CYP4A activity to reduce the production of 20-HETE, alleviate the oxidative stress disorder of the visceral organs, and eventually exert antihypertensive effect. Additionally, the anti-oxidant ability, regulating the renin-angiotensin-aldosterone system and improving endothelial function of M-MJA are more powerful than that of MJA, suggesting that M-MJA may have a better anti-hypertensive effect than MJA. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - March 10, 2019 Category: Complementary Medicine Source Type: research

Effect of Marsdenia tenacissima extract on G2/M cell cycle arrest by upregulating 14-3-3σ and downregulating c-myc in vitro and in vivo
ConclusionG2/M cell cycle arrest occurred by the action of MTE, mediated by the upregulation of 14-3-3σ as well as downregulation of c-myc in MDA-MB-231 and MCF-7 cell lines. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - March 5, 2019 Category: Complementary Medicine Source Type: research

Over-expressing root-specific β-amyrin synthase gene increases glycyrrhizic acid content in hairy roots of Glycyrrhiza uralensis
ConclusionOver-expressing GuBAS root-specifically in hairy roots of G. uralensis enhanced GA accumulation. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - March 5, 2019 Category: Complementary Medicine Source Type: research

Fumigant toxicity and sublethal effects of Teucrium polium (Lamiaceae) essential oil on Aphis fabae Scopoli (Hemiptera: Aphididae)
ConclusionThe results of this study revealed that EO of T. polium could be used as a potential control agent for the aphid. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - March 5, 2019 Category: Complementary Medicine Source Type: research

Tsc1/Tsc2 complex: A molecular target of capsaicin for protection against testicular torsion induced injury in rats
ConclusionCollectively, our findings demonstrate the validity of cap as a therapeutic agent against TT through targeting Tsc1/Tsc2 in a dose-dependent manner. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - March 5, 2019 Category: Complementary Medicine Source Type: research

Scutellarin protects human cardiac microvascular endothelial cells with hypoxia-reoxygenation injury via JAK2/STAT3 signal pathway
ConclusionSCU took a protective effect on HR-treated HCMECs, and the molecular mechanism may be associated with the inhibition of JAK2/STAT3 signal transduction pathway. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - January 31, 2019 Category: Complementary Medicine Source Type: research

After a decade of persistent endeavor, Chinese Herbal Medicine is on the rise
Publication date: January 2019Source: Chinese Herbal Medicines, Volume 11, Issue 1Author(s): De-An Guo, Chang-xiao Liu (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - January 31, 2019 Category: Complementary Medicine Source Type: research

Combination therapy of tripterygium glycosides plus valsartan in diabetic nephropathy treatment: A systematic review and meta-analysis
ConclusionCombination therapy of tripterygium glycosides plus valsartan may be effective for the treatment of DN. However, the safety of the combination therapy need to be further confirmed. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - January 20, 2019 Category: Complementary Medicine Source Type: research

Quantitative and HPLC fingerprint analysis combined with chemometrics for quality evaluation of Codonopsis Radix processed with different methods
Conclusions: Our findings demonstrated that processing method had a big impact on the quality of Codonopsis Radix. Based on the results, the appropriate processing methods directed at different requirements were recommended. The study could lay a foundation for the reasonable processing of Codonopsis Radix in producing areas. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - January 4, 2019 Category: Complementary Medicine Source Type: research