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IVUS and OCT guided primary percutaneous coronary intervention for spontaneous coronary artery dissection with bioresorbable vascular scaffolds
Spontaneous coronary artery dissection (SCAD) is an uncommon but important cause of acute coronary syndrome. The diagnosis of SCAD by an angiogram alone can be challenging and the increasing use of intracoronary imaging has proven an invaluable diagnostic adjunct in this regard. The appropriate initial management of SCAD has been a matter of significant debate. Owing to frequent spontaneous healing of coronary dissection and a higher risk of complications with percutaneous coronary intervention (PCI) in the setting of SCAD, a default approach of mechanical revascularization is not recommended. (Source: Cardiovascular Revas...
Source: Cardiovascular Revascularization Medicine - September 17, 2016 Category: Cardiology Authors: Muhammad Muzaffar Mahmood, David Austin Source Type: research

Impact of Chronic Kidney Disease in Patients Undergoing Percutaneous or Surgical Carotid Artery Revascularization: Insights of the Healthcare Cost and Utilization Project's National Inpatient Sample
This study investigates the impact of chronic kidney disease (CKD) and age on outcomes after carotid artery revascularization. (Source: Cardiovascular Revascularization Medicine)
Source: Cardiovascular Revascularization Medicine - September 6, 2016 Category: Cardiology Authors: Fabio V. Lima, Tzyy Yun M. Yen, Javed Butler, Jie Yang, Jianjin Xu, Luis Gruberg Source Type: research

What Should a Fellow-in-Training Expect at National Cardiovascular Conferences? The Interventional Cardiology Fellows' Perspective
It has become challenging for cardiology fellows-in-training (FIT) to determine which national cardiovascular conference (NCC) to attend given the broad range of meetings and the breadth of information offered. The aim of this study was to report our own experiences of the utility and individual strengths of the NCCs and to further understand the interventional cardiology (IC) FITs' viewpoint regarding the benefits of the individual NCCs. (Source: Cardiovascular Revascularization Medicine)
Source: Cardiovascular Revascularization Medicine - September 5, 2016 Category: Cardiology Authors: Sarkis Kiramijyan, Romain Didier, Edward Koifman, Smita I. Negi Source Type: research

Early Restenose in a Polymer-Free Biolimus A9-coated Stent (BioFreedom): a Case Report based on Optical Coherence Tomography
A 81year old male patient with a severe de novo coronary artery stenosis in the proximal left anterior descending artery was treated with a BioFreedom stent (3.5 ×11mm), three months later, the patient was re-admitted with chest pain and slightly increased troponin. The angiogram showed a significant in-stent restenosis in the recently treated lesion. Optical coherence tomography revealed a fully expanded stent without areas of incomplete stent apposition. Severe immature neointimal hyperplasia without formation of thrombosis was visualized, causing a severe in-stent restenosis. (Source: Cardiovascular Revascularization Medicine)
Source: Cardiovascular Revascularization Medicine - September 5, 2016 Category: Cardiology Authors: Julia Ellert, Lisbeth Antonsen, Lisette Okkels Jensen Source Type: research

Long-term outcome of full plastic jacket treatment for bare metal in-stent restenosis
We report the long-term outcome of a case of “full plastic jacket” treatment consisting of three bioresorbable scaffolds to manage a subtotally occluded left anterior descending artery with associated severe bare metal in-stent restenosis. Angiography 36months' post procedure revealed an excellent result with negative fractional flow reser ve result. Bioresorbable scaffolds may be an attractive option for in-stent restenosis due to the avoidance of an additional metallic layer, and this case is unusual regarding the total scaffold length used and long term angiographic follow-up. (Source: Cardiovascular Revascularization Medicine)
Source: Cardiovascular Revascularization Medicine - September 4, 2016 Category: Cardiology Authors: Richard J. Jabbour, Akihito Tanaka, Antonio Mangieri, Damiano Regazzoli, Marco Ancona, Matteo Pagnesi, Francesco Giannini, Azeem Latib, Antonio Colombo Source Type: research

Long term outcome of full plastic jacket treatment for bare metal in-stent restenosis
We report the long term outcome of a case of “full plastic jacket” treatment consisting of three bioresorbable scaffolds to manage a subtotally occluded left anterior descending artery with associated severe bare metal in-stent restenosis. Angiography 36months' post procedure revealed an excellent result with negative fractional flow reser ve result. Bioresorbable scaffolds may be an attractive option for in-stent restenosis due to the avoidance of an additional metallic layer, and this case is unusual regarding the total scaffold length used and long term angiographic follow-up. (Source: Cardiovascular Revascularization Medicine)
Source: Cardiovascular Revascularization Medicine - September 4, 2016 Category: Cardiology Authors: Richard J. Jabbour, Akihito Tanaka, Antonio Mangieri, Damiano Regazzoli, Marco Ancona, Matteo Pagnesi, Francesco Giannini, Azeem Latib, Antonio Colombo Source Type: research

Serial Optical Coherence Tomography Assessment of Malapposed struts after Everolimus-Eluting Stent implantation. A subanalysis from the HEAL-EES study
Incomplete stent apposition (ISA) is related to stent thrombosis, which is a serious adverse event. We aim to assess the time-course of ISA after 2nd generation everolimus-eluting stent (EES) implantation. (Source: Cardiovascular Revascularization Medicine)
Source: Cardiovascular Revascularization Medicine - September 2, 2016 Category: Cardiology Authors: Kohki Ishida, Shuji Otsuki, Giuseppe Giacchi, Luis Ortega-Paz, Yoshitaka Shiratori, Xavier Freixa, Victoria Mart ín-Yuste, Mónica Masotti, Manel Sabaté, Salvatore Brugaletta Source Type: research

Impact of a Combination of Full Coverage Stenting and Proximal Optimization Technique on Long Term Outcome for Unprotected Distal Left Main Disease
There is no consensual opinion regarding the percutaneous coronary intervention (PCI) procedure for unprotected distal left main (UDLM) lesion. (Source: Cardiovascular Revascularization Medicine)
Source: Cardiovascular Revascularization Medicine - September 2, 2016 Category: Cardiology Authors: Kensuke Takagi, Yusuke Fujino, Toru Naganuma, Yusuke Watanabe, Hiroto Yabushita, Satoru Mitomo, Hiroyoshi Kawamoto, Satoko Tahara, Tsuyoshi Kobayashi, Takayuki Warisawa, Kenichi Karube, Takahiro Matsumoto, Tomohiko Sato, Hisaaki Ishiguro, Naoyuki Kurita, Source Type: research

Association of endothelial dysfunction and No-Reflow during primary percutaneous coronary intervention for ST-elevation myocardial infarction
Coronary no-reflow during primary percutaneous coronary intervention (PPCI) is a predictor of poorer cardiovascular outcome. Both endothelial dysfunction and no-reflow involves abnormal vascular function and hemostasis. Our aim was to assess the association between endothelial dysfunction and no reflow during primary PCI. (Source: Cardiovascular Revascularization Medicine)
Source: Cardiovascular Revascularization Medicine - September 2, 2016 Category: Cardiology Authors: Yaniv Levi, Ayyaz Sultan, Mistre Alemayehu, Sabrina Wall, Shahar Lavi Source Type: research

Bioresorbable scaffolds are here, please handle with care
Summer 2016 carried exciting news for bioresorbable scaffold (BRS) technology. On July 5, the US Food and Drug Administration (FDA) approved the Absorb GT1 (Abbott Vascular) poly(L-lactide) (PLLA)-based BRS for marketing in the United States. Three weeks earlier on June 15, the CE Mark for marketing in Europe was granted for Magmaris (Biotronik), the first metallic bioresorbable Magnesium-based scaffold. These approvals represent important milestones in the development of coronary BRS technology following nearly two decades of research and development from bench to bed. (Source: Cardiovascular Revascularization Medicine)
Source: Cardiovascular Revascularization Medicine - August 31, 2016 Category: Cardiology Authors: Ron Waksman Tags: Editorial Source Type: research

Endovascular Therapy for Ascending Aorta Pseudoaneurysm
Ascending Aortic pseudoaneurysms (AAP) are often formed as a result of prior thoracic surgery. In patients with large AAP, surgical correction is the established therapy. However, a group of patients are not suitable surgical candidates because of advanced age or multiple comorbidities. Instead, endovascular approach represents a viable option in this population. Here, we review the literature of the surgical and trans-catheter therapy for AAP. Additionally, we complement the review with a case presentation of a prohibitive surgical risk case that was treated with endovascular options including an unsuccessful septal occlu...
Source: Cardiovascular Revascularization Medicine - August 29, 2016 Category: Cardiology Authors: Henry C. Quevedo, Alvaro Alonso Source Type: research

Impact of Institutional Volume and Experience with CT Interpretation on Sizing of Transcatheter Aortic Valves: A Multicenter Retrospective Study
Computed tomography (CT) has become the standard imaging modality for pre-procedural aortic annular sizing prior to transcatheter aortic valve replacement (TAVR). We hypothesized that the accuracy of CT derived annular measurements would be greater at sites with higher TAVR procedural volume. (Source: Cardiovascular Revascularization Medicine)
Source: Cardiovascular Revascularization Medicine - August 26, 2016 Category: Cardiology Authors: Divya Ratan Verma, Yash Pershad, Ashish Pershad, Kenith Fang, George Gellert, Michael F. Morris Source Type: research

Pre-hospital ticagrelor in patients with ST-segment elevation myocardial infarction with long transport time to primary PCI facility
Pre-hospital ticagrelor, given less than 1h before coronary intervention (PCI), failed to improve coronary reperfusion in ST-segment elevation myocardial infarction (STEMI) patients undergoing primary PCI. It is unknown whether a longer interval from ticagrelor administration to primary PCI might reveal any improvement of coronary reperfusion. (Source: Cardiovascular Revascularization Medicine)
Source: Cardiovascular Revascularization Medicine - August 20, 2016 Category: Cardiology Authors: Alessandro Lupi, Alon Schaffer, Maurizio Lazzero, Massimo Tessitori, Leonardo De Martino, Andrea Rognoni, Angelo S. Bongo, Italo Porto Source Type: research

Role of optical coherence tomography in managing patients with ST elevation myocardial infarction
Stenting the culprit lesion in patients presenting with acute coronary syndrome (ACS) is the standard of care. Although plaque rupture on an atheromatous lesion is the most common underlying pathology, other mechanisms can also result in ACS presentation; some of which can be managed without stenting. Here we describe a case that was managed conservatively, after evaluating plaque erosion as the underlying mechanism and lack of obstructive lesion. This case highlights the importance of intracoronary imaging to assess the underlying mechanism in patients presenting with acute coronary syndrome. (Source: Cardiovascular Revas...
Source: Cardiovascular Revascularization Medicine - August 20, 2016 Category: Cardiology Authors: Ashish Shah, Douglas J. Ing Source Type: research

Anatomical and procedural determinants of catheter-based renal denervation
Catheter-based renal sympathetic denervation (RDN) can reduce blood pressure (BP) and sympathetic activity in certain patients with uncontrolled hypertension. Less is known about the impact of renal anatomy and procedural parameters on subsequent BP response. (Source: Cardiovascular Revascularization Medicine)
Source: Cardiovascular Revascularization Medicine - August 20, 2016 Category: Cardiology Authors: Sebastian Ewen, Christian Ukena, Thomas Felix L üscher, Martin Bergmann, Peter J. Blankestijn, Erwin Blessing, Bodo Cremers, Oliver Dörr, Dagmara Hering, Lukas Kaiser, Holger Nef, Elias Noory, Markus Schlaich, Faisal Sharif, Isabella Sudano, Britta Voge Source Type: research