Cancer Epidemiology Biomarkers and Prevention This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Telomere Length Is Predictive of Breast Cancer Risk in BRCA2 Mutation Carriers
Conclusions: Blood TL is predictive of breast cancer risk in BRCA2 mutation carriers. Breast cancer cases have significantly shorter TL than unaffected women, regardless of BRCA2 status, indicating that samples taken after breast cancer diagnosis should not be included in evaluations of TL and breast cancer risk. Impact: Our study is built on a well-defined cohort, highly accurate methods, and long follow-up and can therefore help to clarify some previously published, contradictory results. Our findings also suggest that BRCA2 has an important role in telomere maintenance, even in normal blood cells. Cancer Epidemiol Bioma...
Source: Cancer Epidemiology Biomarkers and Prevention - August 1, 2017 Category: Cancer & Oncology Authors: Thorvaldsdottir, B., Aradottir, M., Stefansson, O. A., Bodvarsdottir, S. K., Eyfjörd, J. E. Tags: Research Articles Source Type: research

Total and Free Circulating Vitamin D and Vitamin D-Binding Protein in Relation to Colorectal Cancer Risk in a Prospective Study of African Americans
Conclusions: Our findings suggest that total and free 25-hydroxyvitamin D may be inversely associated with colorectal cancer risk among African Americans. Impact: These findings highlight a potential role for vitamin D in colorectal cancer prevention in African Americans. Cancer Epidemiol Biomarkers Prev; 26(8); 1242–7. ©2017 AACR. (Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - August 1, 2017 Category: Cancer & Oncology Authors: Andersen, S. W., Shu, X.-O., Cai, Q., Khankari, N. K., Steinwandel, M. D., Jurutka, P. W., Blot, W. J., Zheng, W. Tags: Research Articles Source Type: research

A Randomized Double-Blind Placebo-Controlled Trial of the Effect of Vitamin D3 Supplementation on Breast Density in Premenopausal Women
Conclusions: In premenopausal women, one-year supplementation with 1,000, 2,000, or 3,000 IU/day vitamin D3 resulted in a reduction of percent breast density no greater than that seen with the placebo. Impact: At doses of 1,000–3,000 IU/day, vitamin D supplementation will not reduce breast cancer risk through changes in breast density. Cancer Epidemiol Biomarkers Prev; 26(8); 1233–41. ©2017 AACR. (Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - August 1, 2017 Category: Cancer & Oncology Authors: Brisson, J., Berube, S., Diorio, C., Masse, B., Lemieux, J., Duchesne, T., Delvin, E., Vieth, R., Yaffe, M. J., Chiquette, J. Tags: Research Articles Source Type: research

Differential and Joint Effects of Metformin and Statins on Overall Survival of Elderly Patients with Pancreatic Adenocarcinoma: A Large Population-Based Study
Conclusions: Our findings suggest potential benefits of statins on improving survival among elderly PDAC patients; further prospective studies are warranted to corroborate the putative benefit of statin therapy in pancreatic cancer. Impact: Although more studies are needed to confirm our findings, our data add to the body of evidence on potential anticancer effects of statins. Cancer Epidemiol Biomarkers Prev; 26(8); 1225–32. ©2017 AACR. (Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - August 1, 2017 Category: Cancer & Oncology Authors: E, J.-Y., Lu, S.-E., Lin, Y., Graber, J. M., Rotter, D., Zhang, L., Petersen, G. M., Demissie, K., Lu-Yao, G., Tan, X.-L. Tags: Research Articles Source Type: research

Protecting Privacy in Large Datasets--First We Assess the Risk; Then We Fuzzy the Data
Conclusions: Our results show that simple techniques can substantially reduce the risk of reidentification. Impact: Registry owners and large-scale data custodians should consider estimating and if necessary, reducing reidentification risks before sharing large datasets. Cancer Epidemiol Biomarkers Prev; 26(8); 1219–24. ©2017 AACR. (Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - August 1, 2017 Category: Cancer & Oncology Authors: Ursin, G., Sen, S., Mottu, J.-M., Nygard, M. Tags: Research Articles Source Type: research

Thyroid-Stimulating Hormone, Thyroid Hormones, and Risk of Papillary Thyroid Cancer: A Nested Case-Control Study
Conclusions: We found a significantly increased risk of PTC associated with TSH levels below the normal range among women and with TSH levels above the normal range among men. An inverse association between PTC and TSH levels within the normal range was observed among both men and women. Impact: These results could have significant clinical implications for physicians who are managing patients with abnormal thyroid functions and those with thyroidectomy. Cancer Epidemiol Biomarkers Prev; 26(8); 1209–18. ©2017 AACR. (Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - August 1, 2017 Category: Cancer & Oncology Authors: Huang, H., Rusiecki, J., Zhao, N., Chen, Y., Ma, S., Yu, H., Ward, M. H., Udelsman, R., Zhang, Y. Tags: Research Articles Source Type: research

Updated Review of Prevalence of Major Risk Factors and Use of Screening Tests for Cancer in the United States
Much of the suffering and death from cancer could be prevented by more systematic efforts to reduce tobacco use and obesity, improve diet, and increase physical activity and use of established vaccines and screening tests. Monitoring the prevalence of cancer risk factors and preventive tests helps guide cancer prevention and early detection efforts. We provide an updated review, using data through 2015, of the prevalence of major risk factors, cancer screening, and vaccination for U.S. adults and youth. Cigarette smoking among adults decreased to 15.3% in 2015 but remains higher among lower socioeconomic persons (GED: 34.1...
Source: Cancer Epidemiology Biomarkers and Prevention - August 1, 2017 Category: Cancer & Oncology Authors: Sauer, A. G., Siegel, R. L., Jemal, A., Fedewa, S. A. Tags: Reviews Source Type: research

A Review of Pulmonary Toxicity of Electronic Cigarettes in the Context of Smoking: A Focus on Inflammation
The use of electronic cigarettes (e-cigs) is increasing rapidly, but their effects on lung toxicity are largely unknown. Smoking is a well-established cause of lung cancer and respiratory disease, in part through inflammation. It is plausible that e-cig use might affect similar inflammatory pathways. E-cigs are used by some smokers as an aid for quitting or smoking reduction, and by never smokers (e.g., adolescents and young adults). The relative effects for impacting disease risk may differ for these groups. Cell culture and experimental animal data indicate that e-cigs have the potential for inducing inflammation, albeit...
Source: Cancer Epidemiology Biomarkers and Prevention - August 1, 2017 Category: Cancer & Oncology Authors: Shields, P. G., Berman, M., Brasky, T. M., Freudenheim, J. L., Mathe, E., McElroy, J. P., Song, M.-A., Wewers, M. D. Tags: Reviews Source Type: research

Tanning and Teens: Is Indoor Exposure the Tip of the Iceberg?
Because of recent state regulations and the reduced availability of free-standing tanning salons, indoor tanning (IT) prevalence is beginning to decline. This may lead to unintended consequences, such as increases in outdoor intentional tanning. We advance a series of research directions to track and intervene to address all forms of intentional tanning. First, we advocate for enforcement of IT regulation and encourage collection of data on tanning salon compliance and alternative IT strategies. Second, we suggest questions about outdoor and IT should be included in national surveys. Third, we need to understand the potent...
Source: Cancer Epidemiology Biomarkers and Prevention - August 1, 2017 Category: Cancer & Oncology Authors: Hay, J. L., Riley, K. E., Geller, A. C. Tags: Commentary Source Type: research

New Directions in Cancer Control and Population Sciences
Cancer control science has been evolving since it first became a focus for cancer research and program activities a century ago. The evolution of the field has responded to historical megatrends along the way that keep it relevant to the cancer-related needs of society. This commentary describes some of the key trends and developments now influencing cancer control and population sciences that reflect societal change and new tools and concepts in modern biomedical science. New directions include the impact of climate change, health care delivery research, the growth of population health science, data science, precision med...
Source: Cancer Epidemiology Biomarkers and Prevention - August 1, 2017 Category: Cancer & Oncology Authors: Hiatt, R. A. Tags: Commentary Source Type: research

New Evidence on the Association between Prediagnostic Thyroid-Stimulating Hormone Levels and Thyroid Cancer Risk
(Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - August 1, 2017 Category: Cancer & Oncology Authors: Kitahara, C. M. Tags: Editorial Source Type: research

Highlights of This Issue
(Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - August 1, 2017 Category: Cancer & Oncology Tags: Highlights Source Type: research

The Obesity Paradox in Cancer--Moving beyond BMI--Response
(Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - May 31, 2017 Category: Cancer & Oncology Authors: Shachar, S. S., Williams, G. R. Tags: Letters to the Editor Source Type: research

The Obesity Paradox and Cancer--Letter
(Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - May 31, 2017 Category: Cancer & Oncology Authors: Mormile, R. Tags: Letters to the Editor Source Type: research

Aspirin and Pancreatic Cancer--Response
(Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - May 31, 2017 Category: Cancer & Oncology Authors: Risch, H. A. Tags: Letters to the Editor Source Type: research