Etiologic role of root canal infection in apical periodontitis and its relationship with clinical symptomatology
Abstract: Evidence shows the polymicrobial etiology of endodontic infections, in which bacteria and their products are the main agents for the development, progression, and dissemination of apical periodontitis. Microbial factors in necrotic root canals (e.g., endotoxin) may spread into apical tissue, evoking and supporting a chronic inflammatory load. Thus, apical periodontitis is the result of the complex interplay between microbial factors and host defense against invasion of periradicular tissues. This review of the literature aims to discuss the complex network between endodontic infectious content and host immune res...
Source: Brazilian Oral Research - October 18, 2018 Category: Dentistry Source Type: research
Endodontic medicine: interrelationships among apical periodontitis, systemic disorders, and tissue responses of dental materials
Abstract: Endodontic medicine, which addresses the bidirectional relationship between endodontic infections and systemic diseases, has gained prominence in the field of endodontics. There is much evidence showing that while systemic disease may influence the pathogenesis of endodontic infection, endodontic infection can also cause systemic alterations. These alterations include more severe bone resorption and inflammation in the periapical area as well as enhanced systemic disease symptoms. Similarly, many reports have described the impact of systemic diseases on the tissue responses to dental materials. Conversely, the lo...
Source: Brazilian Oral Research - October 18, 2018 Category: Dentistry Source Type: research
Nickel–titanium instruments in endodontics: a concise review of the state of the art
The objective of this literature review is to present and discuss the characteristics of the NiTi alloys used in the major instrumentation systems available in the market, as well as the influence of the metallurgical and mechanical properties of NiTi instruments and the movements that drive them, to enable more accurate and predictable planning of root canal preparation. (Source: Brazilian Oral Research)
Source: Brazilian Oral Research - October 18, 2018 Category: Dentistry Source Type: research
Root canal preparation using micro-computed tomography analysis: a literature review
Abstract: This literature review has critically analyzed the published research related to the biomechanical preparation of root canals with three-dimensional analysis using micro-computed tomography (micro-CT). In December 2017, six databases (PubMed, Cochrane, Web of Science, Embase, Scopus, and Science Direct) were accessed using keywords to find articles including the use of the micro-CT analysis in biomechanical root canal preparation. There were 60 full articles that were selected, which were screened and read by two authors. The research that was reviewed and analyzed included root canal anatomy and sample selection...
Source: Brazilian Oral Research - October 18, 2018 Category: Dentistry Source Type: research
Unprepared root canal surface areas: causes, clinical implications, and therapeutic strategies
This article discloses the reasons why some areas remain unprepared by instruments and discusses strategies to circumvent this issue and enhance infection control during endodontic treatment/retreatment of teeth with apical periodontitis. (Source: Brazilian Oral Research)
Source: Brazilian Oral Research - October 18, 2018 Category: Dentistry Source Type: research
The role of human milk and sucrose on cariogenicity of microcosm biofilms
This study investigated the effect of human milk, alone and associated with sucrose, in the cariogenicity of biofilms in a microcosm biofilm model and compared with the cariogenicity of sucrose and bovine milk. Microcosm biofilms were grown in enamel discs in 24-well plates. Six growth conditions were studied: DMM (chemically defined artificial saliva - negative control), DMM with 1% of sucrose (DMM+s) (positive control), human milk with DMM, human milk with DMM+s, bovine milk with DMM, and bovine milk with DMM+s. After 5 days, the outcome variables surface hardness change (%SHC), microbiological composition of biofilms, a...
Source: Brazilian Oral Research - October 11, 2018 Category: Dentistry Source Type: research
Experimental furcal perforation treated with mineral trioxide aggregate plus selenium: immune response
In conclusion, MTA+Se sealing favoured increased expression of IL-10 and TNF- α at later time points (day 21). (Source: Brazilian Oral Research)
Source: Brazilian Oral Research - October 11, 2018 Category: Dentistry Source Type: research
Influence of ethanol-wet dentin, adhesive mode of application, and aging on bond strength of universal adhesive
Abstract The aim of this study was to evaluate the effect of ethanol on the bond longevity of a universal adhesive system to bovine dentin, under different modes of adhesive application and artificial aging. Bovine dentin was exposed, and the smear layer was standardized by sandpaper polishing. Specimens were randomly divided into 2 groups: ethanol (E) and non-ethanol (N). Groups were subdivided according to adhesive mode of application into etch-and-rinse (Er) and self-etching (S). Resin blocks were built onto the treated surface, and the specimens were stored in deionized water at 37 °C for 48 h. Half of the specimens (...
Source: Brazilian Oral Research - October 11, 2018 Category: Dentistry Source Type: research
Influence of head and linear growth on the development of malocclusion at six years of age: a cohort study
Abstract The aim of this article was to evaluate the influence of biological and sociobehavioral factors on the development of malocclusions in children. This is a cross-sectional study nested in a cohort of 350 children who participated in a community intervention study. After six years, an active search identified 290 children with occlusal abnormalities. Socioeconomic status, linear growth, and nutritional status of the child at birth and at the time of measurement, as well as dietary and sucking habits, were investigated. Malocclusions were evaluated across three spatial planes - anteroposterior, vertical, and transver...
Source: Brazilian Oral Research - October 11, 2018 Category: Dentistry Source Type: research
Influence of a hydrophobic monomer on the physical and mechanical properties of experimental surface sealants
This study evaluated the effect of adding the hydrophobic monomer 1,12 dodecanediol dimethacrylate (DDDMA) to experimental sealants with and without thermocycling on degree of conversion (DC), water sorption (WS), water solubility (WSB), color stability ( Δ E), and micro-shear bond strength ( μ SBS). Five experimental and one commercially available sealant (Bisco - BIS) were tested. The experimental sealants were formulated by mixing different percentages of DDDMA monomers and urethane dimethacrylate (UDMA). The photoinitiator system was composed by camphorquinone (CQ) and tertiary amine 4-ethyl benzoate dimetilamiono (E...
Source: Brazilian Oral Research - October 11, 2018 Category: Dentistry Source Type: research
Nuclear metallothionein in oral squamous cell carcinoma: clinicopathological parameters and patient survival
In conclusion, the present study suggests that metallothionein is not associated with tongue squamous cell carcinoma clinicopathological characteristics and aggressiveness. (Source: Brazilian Oral Research)
Source: Brazilian Oral Research - October 11, 2018 Category: Dentistry Source Type: research
Long-term bonding efficacy of adhesives containing benzodioxioles as alternative co-initiators
In conclusion, benzodioxole derivatives are feasible alternative co-initiators to tertiary amine in camphorquinone-based self-etching dental adhesive formulations. (Source: Brazilian Oral Research)
Source: Brazilian Oral Research - October 11, 2018 Category: Dentistry Source Type: research
Pacifier use modifies the association between breastfeeding and malocclusion: a cross-sectional study
This study aimed to evaluate the influence of breastfeeding and pacifier use on the occlusal status of preschool children. A cross-sectional study was conducted with children (n = 489) aged 2 – 5 years in private and public schools in Pelotas, South Brazil. Mothers answered a questionnaire on demographic, socioeconomic and behavioral variables, including breastfeeding and non-nutritive sucking habits. Malocclusion was classified as normal/mild and moderate/severe, according to WHO criteria. The association between breastfeeding and pacifier use with malocclusion was tested using multivariate logistic regression. The prev...
Source: Brazilian Oral Research - October 11, 2018 Category: Dentistry Source Type: research
Effect of acute administration of nicotine and ethanol on tooth movement in rats
Abstract The aim of this study was to evaluate the effect of acute administration of nicotine and ethanol on tooth movement in rats. Two hundred rats were divided into eight groups: S: saline; N: nicotine; E: ethanol; NE: nicotine and ethanol; SM: saline with tooth movement; NM: nicotine with tooth movement; EM: ethanol with tooth movement; and NEM: nicotine and ethanol with tooth movement. All the solutions were applied for 32, 44, or 58 days, according to the subgroup. Orthodontic movement (25 cN) was initiated 30 days after solution administration in the groups with tooth movement. The rats were euthanized 2, 14, or 28 ...
Source: Brazilian Oral Research - October 11, 2018 Category: Dentistry Source Type: research
Systemic melatonin application increases bone formation in mandibular distraction osteogenesis
This study aimed to investigate the effects of different doses of systemic melatonin application on new bone formation during mandibular distraction osteogenesis (DO) in rats. Mandibular DO was performed on 30 adult female Sprague-Dawley rats, which were randomly divided into three groups: control group (CNT), melatonin dose 1 (MLT-D1), and melatonin dose 2 (MLT-D2). A five-day latent waiting period and a ten-day distraction phase followed the surgery. After the surgery, rats from the MLT-D1 and MLT-D2 groups received 25 and 50 mg/kg melatonin, respectively, at 7, 14, 21, 28, and 35 days. The animals were euthanised 28 day...
Source: Brazilian Oral Research - September 21, 2018 Category: Dentistry Source Type: research
