Combinatorial impact of Sec signal peptides from Bacillus subtilis and bioprocess conditions on heterologous cutinase secretion by Corynebacterium glutamicum
This article is protected by copyright. All rights reserved. (Source: Biotechnology and Bioengineering)
Source: Biotechnology and Bioengineering - November 18, 2018 Category: Biomedical Science Authors: Johannes Hemmerich,
Matthias Moch,
Sarah Jurischka,
Wolfgang Wiechert,
Roland Freudl,
Marco Oldiges Tags: ARTICLE Source Type: research
Mechanisms of Unprimed and Dexamethasone ‐Primed Nonviral Gene Delivery to Human Mesenchymal Stem Cells
This article is protected by copyright. All rights reserved. (Source: Biotechnology and Bioengineering)
Source: Biotechnology and Bioengineering - November 18, 2018 Category: Biomedical Science Authors: Andrew Hamann,
Kelly Broad,
Albert Nguyen,
Angela K. Pannier Tags: ARTICLE Source Type: research
Virus study for continuous low pH viral inactivation inside a coiled flow inverter (CFI)
This study therefore represents a successful virus study concept and experiment for a continuous viral inactivation step. Moreover, it was shown that the transfer from batch results to the continuous process is possible. This is accomplished by the narrow RTD of the CFI, showing how close the setup approaches ideal plug flow and with that batch operation.This article is protected by copyright. All rights reserved. (Source: Biotechnology and Bioengineering)
Source: Biotechnology and Bioengineering - November 18, 2018 Category: Biomedical Science Authors: Laura David,
Benjamin Maiser,
Martin Lobedann,
Peter Schwan,
Michael Lasse,
Horst Ruppach,
Gerhard Schembecker Tags: ARTICLE Source Type: research
A multi ‐site metastasis‐on‐a‐chip microphysiological system for assessing metastatic preference of cancer cells
This article is protected by copyright. All rights reserved. (Source: Biotechnology and Bioengineering)
Source: Biotechnology and Bioengineering - November 18, 2018 Category: Biomedical Science Authors: Julio Aleman,
Aleksander Skardal Tags: COMMUNICATION TO THE EDITOR Source Type: research
Characterizing and Enhancing Virus Removal by Protein A Chromatography
This article is protected by copyright. All rights reserved. (Source: Biotechnology and Bioengineering)
Source: Biotechnology and Bioengineering - November 18, 2018 Category: Biomedical Science Authors: Chinwei Pan,
Alejandro Becerra ‐Arteaga,
Benjamin Tran,
Michael Chinn,
Hua Wang,
Qi Chen,
Herb Lutz,
Min Zhang Tags: ARTICLE Source Type: research
Enhanced production of glutaric acid by NADH oxidase and GabD ‐reinforced bioconversion from L‐lysine
This article is protected by copyright. All rights reserved. (Source: Biotechnology and Bioengineering)
Source: Biotechnology and Bioengineering - November 18, 2018 Category: Biomedical Science Authors: Yoon Gi Hong,
Yu ‐Mi Moon,
Tae‐Rim Choi,
Hye‐Rim Jung,
Soo‐Yeon Yang,
Jung‐Oh Ahn,
Jeong‐Chan Joo,
Kyungmoon Park,
Yun‐Gon Kim,
Shashi Kant Bhatia,
Yoo Kyung Lee,
Yung‐Hun Yang Tags: ARTICLE Source Type: research
Purification of a Conjugated Polysaccharide Vaccine using Tangential Flow Diafiltration
This article is protected by copyright. All rights reserved. (Source: Biotechnology and Bioengineering)
Source: Biotechnology and Bioengineering - November 18, 2018 Category: Biomedical Science Authors: Parinaz Emami,
Seyed Pouria Motevalian,
Erin Pepin,
Andrew L. Zydney Tags: ARTICLE Source Type: research
CFD predicted pH gradients in lactic acid bacteria cultivations
This study verified that the pH gradients during a fermentation in the pilot‐scale bioreactor could be accurately predicted using a coupled simulation of a biokinetic and a CFD model. In order to support the understanding and optimization of industrial‐scale processes, future biokinetic CFD studies need to assess multiple types of environmental gradients, like pH, substrate, and dissolved oxygen, especially at industrial sca le.This article is protected by copyright. All rights reserved. (Source: Biotechnology and Bioengineering)
Source: Biotechnology and Bioengineering - November 18, 2018 Category: Biomedical Science Authors: Robert Spann,
Jens Glibstrup,
Klaus Pellicer ‐Alborch,
Stefan Junne,
Peter Neubauer,
Christophe Roca,
David Kold,
Anna Eliasson Lantz,
Gürkan Sin,
Krist V. Gernaey,
Ulrich Krühne Tags: ARTICLE Source Type: research
Structure of an Engineered Intein Reveals Thiazoline Ring and Provides Mechanistic Insight
This article is protected by copyright. All rights reserved. (Source: Biotechnology and Bioengineering)
Source: Biotechnology and Bioengineering - November 18, 2018 Category: Biomedical Science Authors: C. Seth Pearson,
Reza Nemati,
Binbin Liu,
Jing Zhang,
Matteo Scalabrin,
Zhong Li,
Hongmin Li,
Dan Fabris,
Marlene Belfort,
Georges Belfort Tags: ARTICLE Source Type: research
Low ‐cost Customizable Microscale Toolkit for Rapid Screening and Purification of Therapeutic Proteins
This study demonstrates a versatile and customizable microscale column ( µCol) for biopharmaceutical separations using immobilized metal affinity chromatography (IMAC) as an example application to identify key parameters. µCols have excellent precision, efficiency, and reproducibility, can accommodate any affinity, ion‐exchange or size‐exclusion‐based resin and a re compatible with any HPLC system. µCols reduce reagent amounts, provide comparable purification performance and high‐throughput, and are easy to automate compared to current conventional resin columns. We provide a detailed description of the fabricat...
Source: Biotechnology and Bioengineering - November 18, 2018 Category: Biomedical Science Authors: Abhay U. Andar,
Sevda Deldari,
Erick Gutierrez,
David Burgenson,
Mustafa Al ‐Adhami,
Chandrasekhar Gurramkonda,
Leah Tolosa,
Yordan Kostov,
Douglas D. Frey,
Govind Rao Tags: ARTICLE Source Type: research
Combinatorial impact of Sec signal peptides from Bacillus subtilis and bioprocess conditions on heterologous cutinase secretion by Corynebacterium glutamicum
This article is protected by copyright. All rights reserved. (Source: Biotechnology and Bioengineering)
Source: Biotechnology and Bioengineering - November 18, 2018 Category: Biomedical Science Authors: Johannes Hemmerich,
Matthias Moch,
Sarah Jurischka,
Wolfgang Wiechert,
Roland Freudl,
Marco Oldiges Tags: ARTICLE Source Type: research
Mechanisms of Unprimed and Dexamethasone ‐Primed Nonviral Gene Delivery to Human Mesenchymal Stem Cells
This article is protected by copyright. All rights reserved. (Source: Biotechnology and Bioengineering)
Source: Biotechnology and Bioengineering - November 18, 2018 Category: Biomedical Science Authors: Andrew Hamann,
Kelly Broad,
Albert Nguyen,
Angela K. Pannier Tags: ARTICLE Source Type: research
Virus study for continuous low pH viral inactivation inside a coiled flow inverter (CFI)
This study therefore represents a successful virus study concept and experiment for a continuous viral inactivation step. Moreover, it was shown that the transfer from batch results to the continuous process is possible. This is accomplished by the narrow RTD of the CFI, showing how close the setup approaches ideal plug flow and with that batch operation.This article is protected by copyright. All rights reserved. (Source: Biotechnology and Bioengineering)
Source: Biotechnology and Bioengineering - November 18, 2018 Category: Biomedical Science Authors: Laura David,
Benjamin Maiser,
Martin Lobedann,
Peter Schwan,
Michael Lasse,
Horst Ruppach,
Gerhard Schembecker Tags: ARTICLE Source Type: research
A multi ‐site metastasis‐on‐a‐chip microphysiological system for assessing metastatic preference of cancer cells
This article is protected by copyright. All rights reserved. (Source: Biotechnology and Bioengineering)
Source: Biotechnology and Bioengineering - November 18, 2018 Category: Biomedical Science Authors: Julio Aleman,
Aleksander Skardal Tags: COMMUNICATION TO THE EDITOR Source Type: research
Metallochaperone Function of the Self ‐Subunit Swapping Chaperone Involved in the Maturation of Subunit‐Fused Cobalt Type Nitrile Hydratase
This study brought insights into the maturation of subunit‐fused NHases and confirmed the metallochaperone function of the self‐subunit swapping chaperone.This article is protected by copyright. All rights reserved. (Source: Biotechnology and Bioengineering)
Source: Biotechnology and Bioengineering - November 12, 2018 Category: Biomedical Science Authors: Yuanyuan Xia,
Lukasz Peplowski,
Zhongyi Cheng,
Tianyi Wang,
Zhongmei Liu,
Wenjing Cui,
Michihiko Kobayashi,
Zhemin Zhou Tags: ARTICLE Source Type: research
