Studying host-microbiota interactions in Drosophila melanogaster
Jean KanellopoulosBiomedical Journal 2015 38(4):275-275 (Source: Biomedical Journal)
Source: Biomedical Journal - August 10, 2015 Category: Biomedical Science Authors: Jean Kanellopoulos Source Type: research
Lessons from the Drosophila microbiota
Emma L WaltonBiomedical Journal 2015 38(4):271-274This issue of the Biomedical Journal includes two reviews discussing how studying the gut of the humble fruit fly can reveal important insight about our own microbial communities. In addition, we focus on work showing that acupuncture may not be the best treatment for idiopathic chronic pelvic pain. Finally, we report on several studies that will hopefully help to optimize surgical techniques, from laser treatment for birthmarks to the design of prostheses for radial head fractures. (Source: Biomedical Journal)
Source: Biomedical Journal - August 10, 2015 Category: Biomedical Science Authors: Emma L Walton Source Type: research
Neurilemmoma of lateral nasal wall
We report a case of 18 year old male presented with complaint of nasal obstruction and swelling in right side of nose. We discuss the clinical presentation, histologic features, and therapeutic options for such a rare benign lesion. (Source: Biomedical Journal)
Source: Biomedical Journal - June 11, 2015 Category: Biomedical Science Authors: Jyotsna Naresh BhartiParul GautamPrerna Arora Source Type: research
Results of instrumented posterolateral fusion in treatment of lumbar spondylolisthesis with and without segmental kyphosis: A retrospective investigation
Conclusion: Instrumented PLF resulted in significantly higher osseous fusion rate in patients without segmental kyphosis than in the patients with segmental kyphosis. For the patients with sagittal imbalance, such as rigid or dynamic kyphosis, pedicle-screw fixation cannot ensure successful PLF. Interbody fusion by the posterior lumbar interbody fusion or transforaminal lumbar interbody fusion technique might help overcome this problem. (Source: Biomedical Journal)
Source: Biomedical Journal - June 11, 2015 Category: Biomedical Science Authors: Szu-Yuan ChenMeng-Ling LuChi-Chien NiuTsung-Ting TsaiJen-Chung LiaoLih-Huei ChenWen-Jer Chen Source Type: research
Injectable synthetic bone graft substitute combined with core decompression in the treatment of advanced osteonecrosis of the femoral head: A 5-year follow-up
Conclusions: Core decompression combined with an injectable calcium sulfate and calcium phosphate composite graft (PRO-DENSE) were associated high failure rates in the early postoperative period. It is not recommended for the treatment of ARCO stage IIC and IIIA osteonecrosis of the femoral head. (Source: Biomedical Journal)
Source: Biomedical Journal - June 11, 2015 Category: Biomedical Science Authors: Pei-An YuKuo-Ti PengTsan-Weng HuangRobert Wen-Wei HsuWei-Hsiu HsuMel S Lee Source Type: research
Comparison of the elecsys HBsAg II assay and the architect assay for quantification of hepatitis B surface antigen in chronic hepatitis B patients
Conclusions: There is a significant correlation between Abbott Architect HBsAg QT assay and Roche Elecsys HBsAg II assay. Moreover, HBsAg quantification may potentially provide complementary information about the deduction of the natural course in chronic hepatitis B infection. (Source: Biomedical Journal)
Source: Biomedical Journal - June 11, 2015 Category: Biomedical Science Authors: Chen-Chih LiaoChao-Wei HsuPo-Wen GuChau-Ting YehShi-Ming LinCheng-Tang Chiu Source Type: research
Evaluation of the color durability of acrylic resin veneer materials after immersion in common beverages at different time intervals: A spectrophotometric study
Conclusion: The difference in the color durability of Acrylux and Tooth moulding powder may be attributed to the differences in the composition of tested resin veneering materials, i.e. their polar properties, which contribute to the absorption of staining solution, and the different brands and the strengths of the solutions. (Source: Biomedical Journal)
Source: Biomedical Journal - June 11, 2015 Category: Biomedical Science Authors: Shivani KohliShekhar Bhatia Source Type: research
Impact of fluconazole versus posaconazole prophylaxis on the incidence of fungal infections in patients receiving induction chemotherapy for acute myeloid leukemia
Conclusion: The present study does not distinguish between fluconazole and posaconazole as a primary effective prevention against fungal infections. More prospective studies and meta-analyses are warranted. (Source: Biomedical Journal)
Source: Biomedical Journal - June 11, 2015 Category: Biomedical Science Authors: Camille DevanlayEmmanuelle Tavernier-TardyAurélie BourmaudAlexander Tuan FalkHélène RaberinSandrine MenguyDenis GuyotatNicolas MagnéJérôme Cornillon Source Type: research
Poincare indices for analyzing meditative heart rate signals
Conclusion: The comparative dynamic measures of the Poincare plot indices during and before meditation give more insight of the heart rate signals in a specific psychophysiological state. (Source: Biomedical Journal)
Source: Biomedical Journal - June 11, 2015 Category: Biomedical Science Authors: Atefeh GoshvarpourAteke Goshvarpour Source Type: research
Early radiographic response to epidermal growth factor receptor-tyrosine kinase inhibitor in non-small cell lung cancer patients with epidermal growth factor receptor mutations: A prospective study
Conclusions: A very high percentage (72.4%, 21/29) of NSCLC patients with EGFR mutations with PR demonstrates early radiological response to EGFR-TKIs, which would advocate early radiological examination for EGFR-TKI therapy in NSCLC patients. (Source: Biomedical Journal)
Source: Biomedical Journal - June 11, 2015 Category: Biomedical Science Authors: John WC ChangMing-Mo HouJia-Juan HsiehYun-Chung CheungHung-Ming WangJen-Shi ChenCheng-Hsu WangChih-Hung ChenKun-Yun YehLi-Ying OuChia-Hsun HsiehHong-Dar Isaac WuYing-Tsong ChenIl-Chi ChangShiu-Feng Huang Source Type: research
Serotype distribution and resistance genes associated with macrolide and fluoroquinolone resistance in Streptococcus agalactiae isolates from a hospital in southern Taiwan
Conclusions: The most prevalent GBS serotypes were Ib, III, V, and VI. The ermB and mefE genes carried in serotypes Ib and V were highly associated with the resistance to macrolides and clindamycin. Mutations at codon 79 and codon 83 of ParC were the major determining factors for high-level fluoroquinolone resistance. (Source: Biomedical Journal)
Source: Biomedical Journal - June 11, 2015 Category: Biomedical Science Authors: Ying-Hsiang WangChyi-Liang ChenJiun-Nub HouYi-Rou WangTing-Yu LinMei-Hei WangTsung-Han YangChishih ChuCheng-Hsun Chiu Source Type: research
Peptide immunotherapy in experimental autoimmune encephalomyelitis
Stephen M AndertonBiomedical Journal 2015 38(3):206-214We now have potent drugs available to treat the inflammatory component of multiple sclerosis (MS). However, not all patients respond, the drugs are not curative, and the associated risks to beneficial immune surveillance are considerable. A more desirable approach is to specifically target those comparatively rare T lymphocytes that are orchestrating the autoimmune attack. Using the autoantigen itself to instill immune tolerance in those cells remains a holy grail of immunotherapy. Peptide immunotherapy (PIT) is highly effective at silencing autoimmune responses in exp...
Source: Biomedical Journal - June 11, 2015 Category: Biomedical Science Authors: Stephen M Anderton Source Type: research
Estrogen-mediated protection of experimental autoimmune encephalomyelitis: Lessons from the dissection of estrogen receptor-signaling in vivo
Sophie Laffont, Laure Garnier, Karine Lélu, Jean-Charles GuéryBiomedical Journal 2015 38(3):194-205A growing body of evidence from basic and clinical studies supports the therapeutic potential of estrogens in multiple sclerosis (MS), originating from the well-established reduction in relapse rates observed among women with MS during pregnancy. The biological effects of estrogens are mediated by estrogen receptors (ERα and ERβ). Estrogens or selective ER-agonists have been shown to exert potent neuroprotective or anti-inflammatory effects in experimental autoimmune encephalomy...
Source: Biomedical Journal - June 11, 2015 Category: Biomedical Science Authors: Sophie LaffontLaure GarnierKarine LéluJean-Charles Guéry Source Type: research
T cell mediated pathogenesis in EAE: Molecular mechanisms
Florian C KurschusBiomedical Journal 2015 38(3):183-193T cells are major initiators and mediators of disease in multiple sclerosis (MS) and in its animal model experimental autoimmune encephalomyelitis (EAE). EAE is an antigen-driven autoimmune model in which immunization against myelin autoantigens elicits strong T cell responses which initiate its pathology with CNS myelin destruction. T cells cause pathogenic events by several mechanisms; some work in a direct fashion in the CNS, such as direct cytokine-induced damage, granzyme-mediated killing, or glutamate-induced neurotoxicity, whereas most are indirect mechanisms, s...
Source: Biomedical Journal - June 11, 2015 Category: Biomedical Science Authors: Florian C Kurschus Source Type: research
Experimental autoimmune encephalomyelitis
Jean KanellopoulosBiomedical Journal 2015 38(3):181-182 (Source: Biomedical Journal)
Source: Biomedical Journal - June 11, 2015 Category: Biomedical Science Authors: Jean Kanellopoulos Source Type: research
