Wheat germ and vitamin E decrease BAX/BCL-2 ratio in rat kidney treated with gentamicin
In conclusion, the efficacy of wheat germ as anti-apoptotic and antioxidant was higher than that of vitamin E and it effectively protected against the direct and indirect toxic effects of gentamicin on kidney through regulation of BAX-BCL-2 gene expressions and further inhibition of mitochondrial cytochrome c translocation into cytosol. (Source: Beni Suef University Journal of Basic and Applied Sciences)
Source: Beni Suef University Journal of Basic and Applied Sciences - March 25, 2018 Category: Science Source Type: research

Di-(2-ethylhexyl) Phthalate, a major bioactive metabolite with antimicrobial and cytotoxic activity isolated from River Nile derived fungus Aspergillus awamori
Publication date: Available online 6 February 2018 Source:Beni-Suef University Journal of Basic and Applied Sciences Author(s): Momen M. Lotfy, Hossam M. Hassan, Mona H. Hetta, Ahmed O. El-Gendy, Rabab Mohammed The main objective of this study is to investigate the still unexplored River Nile habitat since it was found little information on the chemistry and biology of the River Nile derived microorganisms. Therefor it was claimed to isolate a number of microorganisms, identify them and test their antimicrobial activities. On the other hand isolation of at least one bioactive metabolite from isolated fungus grown un...
Source: Beni Suef University Journal of Basic and Applied Sciences - March 25, 2018 Category: Science Source Type: research

In vitro and in vivo anthelmintic activity of pumpkin seeds and pomegranate peels extracts against Ascaridia galli
Publication date: Available online 12 February 2018 Source:Beni-Suef University Journal of Basic and Applied Sciences Author(s): Amer R. Abdel Aziz, Mahmoud R. AbouLaila, Mohammad Aziz, Mosaab A. Omar, Khaled Sultan Pumpkin seeds (Cucurbita pepo) and Pomegranate peel (Punica granatum) have anthelmintic properties. The aim of this study was to compare the anthelmintic efficacy of pumpkin seeds ethanolic extract and pomegranate peel aqueous extract against Ascaridia galli in vitro and in vivo in Baladi chicks. On adult worms, the extracts of the two herbs were compared in vitro at concentrations of 25, 50, and 75 mg...
Source: Beni Suef University Journal of Basic and Applied Sciences - March 25, 2018 Category: Science Source Type: research

Synthesis, spectroscopy characterization and biological activities of some novel 1-(3-(N,N-dimethylamino)-1-(5-substituted thiophene-2-yl) propylidene semicarbazone Mannich base derivatives
Publication date: Available online 22 February 2018 Source:Beni-Suef University Journal of Basic and Applied Sciences Author(s): Chandravadivelu Gopi, Magharla Dasaratha Dhanaraju The main aim of this work was to synthesise a novel 1-(3-(N,N-dimethylamino)-1-(5-substituted thiophene-2-yl)propylidene semicarbazone Mannich base derivatives and examine the anti-diabetic and anti-inflammatory activities using alloxan-induced diabetic and carrageenan-induced paw oedema methods. These analogues were prepared by performing a condensation reaction between 1-(thiophen 2-yl) ethanone, formaldehyde, N,N-dimethyl amine hydrochlori...
Source: Beni Suef University Journal of Basic and Applied Sciences - March 25, 2018 Category: Science Source Type: research

Discovery of potential visfatin activators using in silico docking and ADME predictions as therapy for type 2 diabetes
Publication date: Available online 6 March 2018 Source:Beni-Suef University Journal of Basic and Applied Sciences Author(s): Olusola Olalekan Elekofehinti, Oluwamodupe Cecilia Ejelonu, Jean Paul Kamdem, Oluwaseun Benedicta Akinlosotu, Ayodeji Famuti, Damilare Desmond Adebowale, Opeyemi Iwaloye, Yetunde Irinyemi Bulu, Ige Joseph Kade, Joao Batista Teixeira Rocha Visfatin (Nicotinamide phosphoribosyltransferase) is an adipokine implicated in mediating insulin resistance and exhibiting insulin mimetic effect and therefore represents a druggable target for diabetes therapy. About 3,844 peroxisome proliferator activ...
Source: Beni Suef University Journal of Basic and Applied Sciences - March 25, 2018 Category: Science Source Type: research

Isolation and molecular characterization of antifungal metabolite producing actinomycete from mangrove soil
Publication date: Available online 6 March 2018 Source:Beni-Suef University Journal of Basic and Applied Sciences Author(s): Mary Sulakshana Palla, Girija Shankar Guntuku, Murali Krishna Kumar Muthyala, Sirisha Pingali, Prafulla Kumar Sahu The main object of the present study is to isolate and characterize the actinomycetes from Koringa mangrove soil samples near Kakinada, Andhra Pradesh, India. Isolated actinomycetes were assessed for antagonistic activity against various bacteria and fungi. The potent strain KMFA-1 having activity against dermatophytes Candida albicans and Pectinotrichum llanense was characterized...
Source: Beni Suef University Journal of Basic and Applied Sciences - March 25, 2018 Category: Science Source Type: research

Development and screening of mutants from Monascus sanguineus for secondary metabolites production
Publication date: Available online 9 March 2018 Source:Beni-Suef University Journal of Basic and Applied Sciences Author(s): Rashmi Dikshit, Padmavathi Tallapragada Present study was carried out to develop a potent mutant for enhancing secondary metabolite production from Monascus sanguineus. Ultraviolet (UV) treatment as physical and Ethyl methane sulphonate (EMS) as chemical mutagen was used to cultivate the mutants. All obtained mutants were screened for growth and pigment yield on three different synthetic media namely; potato dextrose agar (PDA), malt glucose peptone agar (MGPA) and Czapek Dox yeast extract Agar (...
Source: Beni Suef University Journal of Basic and Applied Sciences - March 25, 2018 Category: Science Source Type: research

BNP as a promising marker in prediction of malignant arrhythmias in pts with LV systolic dysfunction after an acute MI
Publication date: Available online 10 March 2018 Source:Beni-Suef University Journal of Basic and Applied Sciences Author(s): Ahmed Yassin, MohamedAbo Hamila, Ahmed Battah, Amal Rizk, SheriefMokhtar (Source: Beni Suef University Journal of Basic and Applied Sciences)
Source: Beni Suef University Journal of Basic and Applied Sciences - March 25, 2018 Category: Science Source Type: research

Seasonal and spatial variation of aquatic macrophytes and phytoplankton community at El-Quanater El-Khayria River Nile, Egypt
In this study, the phytoplankton biomass and species composition in El-Quanater El-Khayria (River Nile, Egypt) was analyzed at four sampling sites on a program of a seasonally sampling and supported by measurements of different water variables as well as biomass production of most common aquatic macrophytes. The major species of aquatic macrophytes were two submerged species (Ceratophyllum demersum and Ceratophyllum submersum), two emergent (Polygonum tomentosum and spontaneum), and one free floating aquatic macrophyte (Eichhornia crassipes). Considerable seasonal variations in water quality as well as macrophytes biomass ...
Source: Beni Suef University Journal of Basic and Applied Sciences - March 25, 2018 Category: Science Source Type: research

Amelioration of DENA-induced oxidative stress in rat kidney and brain by the essential oil of Elettaria cardamomum
Publication date: Available online 15 March 2018 Source:Beni-Suef University Journal of Basic and Applied Sciences Author(s): Nihal M. Elguindy, Galila A. Yacout, Eman F. El Azab The goal of the present work was to study the protective role of the essential oil of Elettaria cardamomum (cardamom) against diethylnitrosamine (DENA)-induced oxidative stress in the kidney and brain of rats in comparison with geraniol, a pure compound as one of the main components of cardamom essential oil. Geraniol or cardamom essential oil was orally administered every day (100 and 200 mg/kg) for 1 week before DENA administration and ...
Source: Beni Suef University Journal of Basic and Applied Sciences - March 25, 2018 Category: Science Source Type: research

Water demand and waste management with respect to projected urban growth of Gurugram city in Haryana
Publication date: Available online 17 March 2018 Source:Beni-Suef University Journal of Basic and Applied Sciences Author(s): Anil Kumar Misra, Misbah Masoodi, Rohith P. Poyil Gurugram city (Haryana state) has witnessed unprecedented urban growth over the past two decades, owing to the escalation in population, immigration and unorganized expansion. Present study examines the spatial determinants and different features of urban growth till 2011 in the Gurugram city and based on the growth rates and probable demands, land use pattern changes for 2031, 2041 and 2051 have been projected. Using photogrammetric analysis, o...
Source: Beni Suef University Journal of Basic and Applied Sciences - March 25, 2018 Category: Science Source Type: research

Variation in seasonal prevalence and intensity of progenetic metacercariae of Clinostomum complanatum infection in Trichogaster fasciatus fish
Publication date: Available online 19 March 2018 Source:Beni-Suef University Journal of Basic and Applied Sciences Author(s): Shabnam Khan, Sakil Ahmed, M. Serajuddin, Mohammad Khalid Saifullah A total of 1242 out of 1484 Trichogaster fasciatus fish were found to be infected with metacercarial stage of Clinostomum complanatum where 14,258 parasites were recorded mainly from the peritoneal cavity, gills and viscera during five years of study period. The seasonal variations in prevalence, intensity and abundance of the parasitic infection were assessed. The maximum and minimum values of prevalence of metacercarial infe...
Source: Beni Suef University Journal of Basic and Applied Sciences - March 25, 2018 Category: Science Source Type: research

Distribution of two monogenean (Gastrocotylidae) from the north atlantic coast of Morocco
In this study, we also discuss the relation of the fish infection in terms of length and sex. (Source: Beni Suef University Journal of Basic and Applied Sciences)
Source: Beni Suef University Journal of Basic and Applied Sciences - March 25, 2018 Category: Science Source Type: research

Morphological, histological and ultrastructural studies on the exocrine pancreas of goose.
This study was conducted on the pancreas of ten healthy mature birds of goose. The pancreas was excised from the duodenum rapidly after slaughter of the birds. The specimens were fixed in 10% buffered neutral formalin then processed for light and electron microscopic study. The macroscopic observations revealed that goose pancreas was located in the right side of the abdomen between the ascending and descending loops of duodenum. It was formed from dorsal, splenic, ventral and third lobes. The histological observations revealed that the pancreas was formed of lobules of serous acini. The secretory acinus unit was appearing...
Source: Beni Suef University Journal of Basic and Applied Sciences - March 25, 2018 Category: Science Source Type: research

Optimization of the anticonvulsant activity of 2-acetamido-N-benzyl-2-(5-methylfuran-2-yl) acetamide using QSAR modeling and molecular docking techniques
Publication date: Available online 24 March 2018 Source:Beni-Suef University Journal of Basic and Applied Sciences Author(s): Adedirin Oluwaseye, Adamu Uzairu, Gideon A. Shallangwa, Stephen E. Abechi Chemometric descriptors were used to analyze quantitatively the anticonvulsant activity of ninety propanamide derivatives. Molecular geometries of the data set were optimized with B3LYP/6-31G∗∗ quantum mechanical method and chemometric descriptors were calculated from the optimized structure. Linear QSAR models were developed using genetic function algorithm. Predictive capabilities of the models were evaluated using...
Source: Beni Suef University Journal of Basic and Applied Sciences - March 25, 2018 Category: Science Source Type: research