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Incidence of Negative Appendicectomy: Correlation Between Clinical, Peroperative and Histopathological Findings
Appendicitis is one of the most difficult diagnostic problems to confront the emergency physician and it is the most common intra-abdominal condition requiring emergency surgery. The term “Negative appendicectomy” used for operation done for suspected appendicitis, in which the appendix is found to be normal on histological evaluation. The study aimed to find out the incidence of negative appendicectomy evaluating the correlation between clinical, per-operative and histopathologi cal findings. It was a prospective study of 100 cases clinically diagnosed as acute appendicitis selected over a period of one year (July 200...
Source: Bangladesh Medical Research Council Bulletin - April 17, 2017 Category: International Medicine & Public Health Source Type: research

Continuation of Indoor Prescribed Antibiotics in the Outpatient Treatment of Neonatal Sepsis
Neonatal sepsis is a common problem whose antibiotic treatment is usually recommended whilst admitted in hospital for at least 10-14 days. Families in Bangladesh however are reluctant to stay in hospital to complete the treatment for such a long time due to reasons such as financial difficulties and either or both are working parents. This leads to incomplete treatment of neonatal sepsis. We hypothesised that after initial improvement in neonatal sepsis with injectable antibiotics whilst admitted, the same treatment could be safely continued in the outpatient setting to complete the full course. This intervention study was...
Source: Bangladesh Medical Research Council Bulletin - April 17, 2017 Category: International Medicine & Public Health Source Type: research

Role of Whole-Body Tc 99m MDP Bone Scintigraphy for Evaluating Skeletal Metastasis in Patients with Lung Cancer
Lung cancer is the third most common site of origin of metastatic cancer deposits in bone, after breast and prostate. It ’s metastasis to bone is one of the most aggressive tumors and has a very unfavorable prognosis.  This retrospective descriptive study was designed to detect the skeletal metastasis of   carcinoma (Ca) lung patient by Tc 99m MDP bone scan.The medical records of all patients attended between January 2015 and July 2015 with a diagnosis of lung cancer were reviewed. Lung cancer in all patients was confirmed pathologically, and patients underwent whole-body bone scan for evaluating skeletal metastasis. ...
Source: Bangladesh Medical Research Council Bulletin - April 17, 2017 Category: International Medicine & Public Health Source Type: research

Socio-demographic Determinants of Water Treatment in Cholera Patients and Clinical Presentation of Disease: A Decade of Observation from a Large Urban Diarrhoeal Disease Hospital in Bangladesh
Cholera remains a health problem around the globe including Bangladesh, and  claims thousands of lives and places a substantial strain on public health resources. Data collected from 4,894 cholera patients who presented to Dhaka Hospital of icddr,b between 2004 and 2013, and were analysed to assess the socio-demographic determinants of water treatment and their impact on c holera, and examine the possible influence of water treatment on changing clinico-pathologic predictors in cholera patients. Results of this study consistently showed strong association between water treatment and male sex, family income, slum residence...
Source: Bangladesh Medical Research Council Bulletin - April 17, 2017 Category: International Medicine & Public Health Source Type: research

Role of MDCT Scan in the Evaluation of Pancreatic Mass with Histopathological Correlation
Diagonstic imaging plays a critical role in evaluation of the adenocarcinoma of the pancreas- the 4th leading cause of death for the cancer globally. The purpose of this study was to determine the role of multidetector computed tomography (MDCT) in evaluation of pancreatic tumors. The prospective and study was carried out in Dhaka, Bangladesh during the period of July, 2013 to December 2014. Amongst 47 publish with suspected pancreatic lesion (having positive CT scan findings). Patients underwent histopathology of their lesions, the report of which was used as gold standard for comparing the role of CT scan in evaluating s...
Source: Bangladesh Medical Research Council Bulletin - April 17, 2017 Category: International Medicine & Public Health Source Type: research

Molecular Analysis of HLA-DR and Their Association with Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is an autoimmune disease that develops within a complex network of genetic and immunologic factors. Both genetic and environmental factors strongly influence the      development of SLE. But genetic factors are more important both in determining the overall susceptibility to SLE and in influencing immunologic heterogenecity in affected subjects. Now it is accepted that major histocompatibility complex (MHC) genes particularly HLA (Human leukocyte antige n) class II constitute a part of the genetic factor for susceptibility to develop SLE. To determine the association of HLA-DR antige...
Source: Bangladesh Medical Research Council Bulletin - April 17, 2017 Category: International Medicine & Public Health Source Type: research

Biochemical Bone Markers for Early Detection of Osteopaenia of Prematurity
Osteopaenia of prematurity (OOP) imposes the risk of fractures and growth failure to premature infants. Studies have investigated the validity of biochemical markers of osteopaenia but till date it is not established. So, this study was intended to examine the diagnostic performance of biochemical markers in early detection of osteopaenia of prematurity. This prospective study was conducted in the Neonatal Intensive Care Unit (NICU), Department of Neonatology, Bangabandhu Sheikh Mujib Medical University during June 2013 to February 2014. A total of 100 premature infants with gestational age ≤ 34 weeks were consecutively ...
Source: Bangladesh Medical Research Council Bulletin - April 17, 2017 Category: International Medicine & Public Health Source Type: research