Auditory brainstem response in infants and children with autism spectrum disorder: A meta ‐analysis of wave V
Infants with autism spectrum disorder (ASD) were recently found to have prolonged auditory brainstem response (ABR); however, at older ages, findings are contradictory. We compared ABR differences between participants with ASD and controls with respect to age using a meta‐analysis. Data sources included MEDLINE, EMBASE, Web of Science, Google Scholar, HOLLIS, and ScienceDirect from their inception to June 2016. The 25 studies that were included had a total of 1349 participants (727 participants with ASD and 622 controls) and an age range of 0–40 years. Prolongation of the absolute latency of wave V in ASD had a signifi...
Source: Autism Research - October 31, 2017 Category: Psychiatry Authors: Oren Miron, Andrew L. Beam, Isaac S. Kohane Tags: Research Article Source Type: research
---
Autism Research,Volume 11, Issue 2, Page 296-304, February 2018. (Source: Autism Research)
Source: Autism Research - October 20, 2017 Category: Psychiatry Source Type: research
Sensorimotor learning and associated visual perception are intact but unrelated in autism spectrum disorder
Humans show an astonishing capability to learn sensorimotor behaviours. However, data from sensorimotor learning experiments suggest the integration of efferent sensorimotor commands, afferent sensorimotor information, and visual consequences of a performed action during learning is different in autism, leading to atypical representation of internal action models. Here, we investigated the generalization of a sensorimotor internal action model formed during sensorimotor learning to a different, but associated, visual perception task. Although motor timing was generally less accurate in adults with autism, following practic...
Source: Autism Research - October 20, 2017 Category: Psychiatry Authors: Spencer J. Hayes, Matthew Andrew, Nathan C. Foster, Digby Elliott, Emma Gowen, Simon J. Bennett Tags: Research Article Source Type: research
INSAR President's Message – October 2017
(Source: Autism Research)
Source: Autism Research - October 19, 2017 Category: Psychiatry Tags: SOCIETY PAGE Source Type: research
Scientific Summaries for Families with ASD
(Source: Autism Research)
Source: Autism Research - October 19, 2017 Category: Psychiatry Tags: SCIENTIFIC SUMMARIES FOR FAMILIES WITH ASD Source Type: research
Issue Information
(Source: Autism Research)
Source: Autism Research - October 19, 2017 Category: Psychiatry Tags: ISSUE INFORMATION Source Type: research
Disrupted integration of exteroceptive and interoceptive signaling in autism spectrum disorder
In addition to deficits in social communication, individuals diagnosed with Autism Spectrum Disorder (ASD) frequently exhibit changes in sensory and multisensory function. Recent evidence has focused on changes in audiovisual temporal processing, and has sought to relate these sensory‐based changes to weaknesses in social communication. These changes in audiovisual temporal function manifest as differences in the temporal epoch or “window” within which paired auditory and visual stimuli are integrated or bound, with those with ASD exhibiting expanded audiovisual temporal binding windows (TBWs). However, it is unknown...
Source: Autism Research - October 14, 2017 Category: Psychiatry Authors: Jean ‐Paul Noel, Marisa Lytle, Carissa Cascio, Mark T. Wallace Tags: Research Article Source Type: research
---
Autism Research,Volume 11, Issue 2, Page 234-244, February 2018. (Source: Autism Research)
Source: Autism Research - October 13, 2017 Category: Psychiatry Source Type: research
Virtual Environment for Social Information Processing: Assessment of Children with and without Autism Spectrum Disorders
This study presents preliminary evidence of VESIP's usefulness for measuring SIP skills in children with and without autism spectrum disorders (ASD). Twenty‐one children with ASD and 29 control children participated. It was hypothesized that (a) children (8–12 years old), with and without ASD, would understand and interact effectively with VESIP; (b) VESIP scores would be reliable in both populations; and (c) children with ASD would score lower on SIP domains than typically developing peers. Results supported these hypotheses. Finally, response bias was also evaluated, showing that children with ASD have different prob...
Source: Autism Research - October 1, 2017 Category: Psychiatry Authors: Nicole Russo ‐Ponsaran, Clark McKown, Jason Johnson, Jaclyn Russo, Jacob Crossman, Ilana Reife Tags: Research Article Source Type: research
Joint effects of prenatal air pollutant exposure and maternal folic acid supplementation on risk of autism spectrum disorder
We examined the joint effects of gestational FA and air pollution exposures in association with ASD. We studied 346 ASD cases and 260 typically developing controls from the CHARGE case‐control study. Self‐reported FA intake for each month of pregnancy was quantified. Estimates of exposure to near roadway air pollution (NRP) and criteria air pollutant measures were assigned based on maternal residential history. Among mothers with high FA intake (>800 μg) in the first pregnancy month, exposure to increasing levels of all air pollutants, except ozone, during the first trimester was associated with decreased ASD risk,...
Source: Autism Research - October 1, 2017 Category: Psychiatry Authors: Amanda J. Goodrich, Heather E. Volk, Daniel J. Tancredi, Rob McConnell, Fred W. Lurmann, Robin L. Hansen, Rebecca J. Schmidt Tags: Research Article Source Type: research
Pupillary Response and Phenotype in ASD: Latency to Constriction Discriminates ASD from Typically Developing Adolescents
This study used eye‐tracking equipment and a hand‐held penlight to measure the pupil reflex in adolescents with “high functioning” ASD and in adolescents without ASD. The ASD group showed a delay in pupil response. This is the first eye‐tracking study to conduct this test as typically performed by a clinical provider, demonstrating differences in older individuals with a subtype of ASD. (Source: Autism Research)
Source: Autism Research - October 1, 2017 Category: Psychiatry Authors: Georgina T.F. Lynch, Stephen M. James, Mark VanDam Tags: Research Article Source Type: research
What will my child's future hold? phenotypes of intellectual development in 2 –8‐year‐olds with autism spectrum disorder
We examined phenotypes of autism spectrum disorder (ASD) based on trajectories of intellectual development from early (ages 2–3 ½) to middle (ages 5–8) childhood in a recent clinically ascertained cohort. Participants included 102 children (82 males) initially diagnosed with ASD from the Autism Phenome Project longitudinal sample. Latent class growth analysis was used to identify distinct IQ trajectories. Baseline and developmental course differences among groups were assessed using univariate techniques and repeated measures regression models, respectively. A four class model best represented the data. Using the high...
Source: Autism Research - October 1, 2017 Category: Psychiatry Authors: Marjorie Solomon, Ana ‐Maria Iosif, Vanessa P. Reinhardt, Lauren E. Libero, Christine W. Nordahl, Sally Ozonoff, Sally J. Rogers, David G. Amaral Tags: Research Article Source Type: research
Shank3 ‐Deficient rats exhibit degraded cortical responses to sound
In this study, we document the auditory cortex response to speech and non‐speech sounds in the novel Shank3‐deficient rat model. We predicted that the auditory cortex response to sounds would be impaired in Shank3‐deficient rats. We found that auditory cortex responses were weaker in Shank3 heterozygous rats compared to wild‐type rats. Additionally, Shank3 heterozygous responses had less spontaneous auditory cortex firing and were unable to respond well to rapid trains of noise bursts. The rat model of the auditory impairments in SHANK3 mutation could be used to test potential rehabilitation or drug therapies to im...
Source: Autism Research - October 1, 2017 Category: Psychiatry Authors: Crystal T. Engineer, Kimiya C. Rahebi, Michael S. Borland, Elizabeth P. Buell, Kwok W. Im, Linda G. Wilson, Pryanka Sharma, Sven Vanneste, Hala Harony ‐Nicolas, Joseph D. Buxbaum, Michael P. Kilgard Tags: Research Article Source Type: research
---
Autism Research,Volume 11, Issue 2, Page 284-295, February 2018. (Source: Autism Research)
Source: Autism Research - September 27, 2017 Category: Psychiatry Source Type: research
---
Autism Research,Volume 11, Issue 2, Page 270-283, February 2018. (Source: Autism Research)
Source: Autism Research - September 21, 2017 Category: Psychiatry Source Type: research
