Asthma in children of mothers with systemic lupus erythematosus and the role of preterm birth
ConclusionPrevalent maternal SLE during pregnancy is associated with an increased risk of asthma in the offspring. While preterm birth can explain a fair proportion of this association, additional unidentified mechanisms are also likely to play a role.This article is protected by copyright. All rights reserved. (Source: Arthritis Care and Research)
Source: Arthritis Care and Research - November 10, 2017 Category: Rheumatology Authors: Marios Rossides, Cathina Nguyen, Elizabeth V. Arkema, Julia F. Simard Tags: Brief Report Source Type: research
Comorbidities in Spondyloarthritis associate with poor function, work disability and quality of life: Results from the ASAS ‐COMOSPA study
ConclusionComorbidities in SpA adversely influence physical function, work ability and quality of life and are important to take into account in daily clinical practice.This article is protected by copyright. All rights reserved. (Source: Arthritis Care and Research)
Source: Arthritis Care and Research - November 10, 2017 Category: Rheumatology Authors: E. Nikiphorou, S. Ramiro, D. Heijde, S. Norton, A. Molt ó, M. Dougados, F. van den Bosch, R. Landewé, Tags: Brief Report Source Type: research
Efficacy of hydroxychloroquine in hand osteoarthritis: a randomized, double blind, placebo ‐controlled trial
ConclusionsTreatment with HCQ (24 weeks) is not effective in reducing the symptoms of hand OA compared to placebo.This article is protected by copyright. All rights reserved. (Source: Arthritis Care and Research)
Source: Arthritis Care and Research - November 10, 2017 Category: Rheumatology Authors: Weiching Lee, Liesbeth Ruijgrok, Bianca Boxma ‐de Klerk, Marc R. Kok, Margreet Kloppenburg, Andreas Gerards, Margriet Huisman, Mieke Hazes, Peter de Sonnaville, Bart Grillet, Angelique Weel, Natalja Basoski Tags: Original Article Source Type: research
Early Rheumatoid Arthritis Presentation, Treatment and Outcomes in Aboriginal Patients in Canada: A Canadian Early Arthritis Cohort Study Analysis
ConclusionsAboriginal ERA patients experienced worse disease outcomes. This may reflect unmeasured biological differences and/or disparities in prognostic factors informed by inequities in determinants of health. The appropriateness of current treatment strategies applied in different contexts should be considered.This article is protected by copyright. All rights reserved (Source: Arthritis Care and Research)
Source: Arthritis Care and Research - November 10, 2017 Category: Rheumatology Authors: Sujay Nagaraj, Cheryl Barnabe, Orit Schieir, Janet Pope, Susan J. Bartlett, Gilles Boire, Edward Keystone, Diane Tin, Boulos Haraoui, J Carter Thorne, Vivian P. Bykerk, Carol Hitchon, Tags: Brief Report Source Type: research
Arthritis after cancer immunotherapy: symptom duration and treatment response
ConclusionMusculoskeletal irAEs can manifest as an RA‐like polyarthritis, oligoarthritis, tenosynovitis, or PMR. Musculoskeletal symptoms can last more than a year, but they can generally be managed with low to moderate doses of corticosteroids.This article is protected by copyright. All rights reserved. (Source: Arthritis Care and Research)
Source: Arthritis Care and Research - November 10, 2017 Category: Rheumatology Authors: Melanie H. Smith, Anne R. Bass Tags: Brief Report Source Type: research
Demographic and Clinical Factors Associated with Non ‐Surgical Osteoarthritis Treatment Use Among Patients in Outpatient Clinics
ConclusionResults suggest potential under‐utilization of therapies other than oral analgesia. Patient characteristics may affect OA treatment use, and understanding the relationship between these factors and OA treatment preferences may improve adherence to OA treatment guidelines.This article is protected by copyright. All rights reserved. (Source: Arthritis Care and Research)
Source: Arthritis Care and Research - November 10, 2017 Category: Rheumatology Authors: Lauren M. Abbate, Amy S. Jeffreys, Cynthia J. Coffman, Todd A. Schwartz, Liubov Arbeeva, Leigh F. Callahan, Nicole A. Negbenebor, Wendy M. Kohrt, Robert S. Schwartz, Ernest. Vina, Kelli D. Allen Tags: Original Article Source Type: research
Profiling Response to TNF ‐Inhibitor Treatment in Axial Spondyloarthritis
ConclusionsPrimary lack of response accounted nearly 40% of the TNFi failures in AxSpA patients. Older age, negative HLA‐B27, higher baseline disease activity and treatment with sTNFR were the independent predictors of the primary non‐response to TNFi.This article is protected by copyright. All rights reserved. (Source: Arthritis Care and Research)
Source: Arthritis Care and Research - November 10, 2017 Category: Rheumatology Authors: Mansour Alazmi, Ismail Sari, Bharath Krishnan, Robert D. Inman, Nigil Haroon Tags: Original Article Source Type: research
Value of RAPID3 in patients with PsA: results from the TICOPA and LOPAS II databases
ConclusionRAPID3 appears comparably informative to PASDAS and DAPSA in PsA, with greater feasibility for routine clinical care.This article is protected by copyright. All rights reserved. (Source: Arthritis Care and Research)
Source: Arthritis Care and Research - November 7, 2017 Category: Rheumatology Authors: Laura C Coates, William Tillett, Gavin Shaddick, Theodore Pincus, Arthur Kavanaugh, Philip S Helliwell Tags: Original Article Source Type: research
The association of femoroacetabular impingement and delayed gadolinium enhanced mri of cartilage (dgemric): a population ‐based study
ConclusionSubjects with mixed FAI had reduced T1 RVs compared other FAI subtypes. No substantial cartilage degeneration was found in pure cam or pincer FAI compared to non‐FAI hips. These results indicate that the presence of cam or pincer impingements alone does not suggest the beginning of cartilage degeneration. In contrast, the presence of both FAI subtypes is a risk factor for early cartilage damage.This article is protected by copyright. All rights reserved. (Source: Arthritis Care and Research)
Source: Arthritis Care and Research - November 7, 2017 Category: Rheumatology Authors: Yimeng Guo, Honglin Zhang, Hong Qian, David R. Wilson, Hubert Wong, Morgan Barber, Bruce B. Forster, John Esdaile, Jolanda Cibere, Tags: Original Article Source Type: research
Reductions in Radiographic Progression in Early Rheumatoid Arthritis Over Twenty ‐Five Years: Changing Contribution From Rheumatoid Factor in Two Multicenter UK Inception Cohorts
ConclusionRadiographic progression was shown to be significantly reduced between the 2 cohorts, and was associated with lower baseline damage and other factors, including changes in early disease‐modifying antirheumatic drug use. The impact of RF status as a prognostic marker of clinically meaningful change in radiographic progression has markedly diminished in the context of more modern treatment. (Source: Arthritis Care and Research)
Source: Arthritis Care and Research - November 6, 2017 Category: Rheumatology Authors: Lewis Carpenter, Sam Norton, Elena Nikiphorou, Keeranur Jayakumar, Daniel F. Mcwilliams, Kirsten L. Rennie, Josh Dixey, Patrick Kiely, David Andrew Walsh, Adam Young, Tags: Original Article Source Type: research
Severity of disease, and not glucocorticoid use, determines outcomes in systemic lupus: comment on the article by Sheane et al
(Source: Arthritis Care and Research)
Source: Arthritis Care and Research - November 6, 2017 Category: Rheumatology Authors: Aryeh M. Abeles, Micha Abeles Tags: Letters Source Type: research
Impact of Obesity and Adiposity on Inflammatory Markers in Patients With Rheumatoid Arthritis
ConclusionObesity is associated with higher CRP levels and ESR in women with RA. This association is related to fat mass and not RA disease activity. Low BMI is associated with higher CRP levels in men with RA; this unexpected finding remains incompletely explained but likely is not a direct effect of adiposity. (Source: Arthritis Care and Research)
Source: Arthritis Care and Research - November 6, 2017 Category: Rheumatology Authors: Michael D. George, Jon T. Giles, Patricia P. Katz, Bryant R. England, Ted R. Mikuls, Kaleb Michaud, Alexis R. Ogdie ‐Beatty, Said Ibrahim, Grant W. Cannon, Liron Caplan, Brian C. Sauer, Joshua F. Baker Tags: Original Article Source Type: research
Cutaneous and Systemic Findings Associated With Nuclear Matrix Protein 2 Antibodies in Adult Dermatomyositis Patients
ConclusionDermatomyositis patients with anti–NXP‐2 antibodies have a distinct and often severe systemic phenotype that includes myalgia, peripheral edema, and significant dysphagia, despite having milder inflammatory skin disease. (Source: Arthritis Care and Research)
Source: Arthritis Care and Research - November 2, 2017 Category: Rheumatology Authors: Anna Rogers, Lorinda Chung, Shufeng Li, Livia Casciola ‐Rosen, David F. Fiorentino Tags: Original Article Source Type: research
Impact of Moving From a Widespread to Multisite Pain Definition on Other Fibromyalgia Symptoms
ConclusionThis large‐scale study demonstrates that regardless of the pain definition used, the magnitude of association between pain and other associated symptoms of fibromyalgia is similar. This finding supports the continued collection of both when classifying fibromyalgia, but highlights the fact that pain may not require to follow the definition outlined within the 1990 American College of Rheumatology criteria. (Source: Arthritis Care and Research)
Source: Arthritis Care and Research - November 2, 2017 Category: Rheumatology Authors: Linda E. Dean, Lesley Arnold, Leslie Crofford, Robert Bennett, Don Goldenberg, Mary ‐Ann Fitzcharles, Eduardo S. Paiva, Roland Staud, Dan Clauw, Piercarlo Sarzi‐Puttini, Gareth T. Jones, Abimbola Ayorinde, Elisa Flüß, Marcus Beasley, Gary J. Macfarl Tags: Original Article Source Type: research
Comparative Effectiveness of Mycophenolate Mofetil for the Treatment of Juvenile ‐Onset Proliferative Lupus Nephritis
ConclusionMMF was more beneficial than other therapies in improving/maintaining long‐term renal function in patients with juvenile‐onset PLN up to a maximum followup of 7 years. This finding is consistent with evidence from adult PLN clinical trials. (Source: Arthritis Care and Research)
Source: Arthritis Care and Research - November 2, 2017 Category: Rheumatology Authors: Simon Y. Tian, Earl D. Silverman, Eleanor Pullenayegum, Patrick E. Brown, Joseph Beyene, Brian M. Feldman Tags: Original Article Source Type: research
