Current uses of intracranial vessel wall imaging for clinical practice: a high-resolution MR technique recently available
ABSTRACT Intracranial vessel wall imaging plays an increasing role in diagnosing intracranial vascular diseases. With the growing demand and subsequent increased use of this technique in clinical practice, radiologists and neurologists should be aware of the choices in imaging parameters and how they affect image quality, clinical indications, methods of assessment, and limitations in the interpretation of these images. Due to the improvement of the MRI techniques, the possibility of accurate and direct evaluation of the abnormalities in the arterial vascular wall (vessel wall imaging) has evolved, adding substantial data ...
Source: Arquivos de Neuro-Psiquiatria - November 2, 2020 Category: Neurology Source Type: research

Dietary habits in a group of patients with multiple sclerosis are similar to those of healthy control subjects
Conclusion: The dietary patterns of patients with MS and healthy controls were similar in the city of Santos, S ão Paulo, Brazil, and surrounding towns, except for higher intake of carbohydrates by patients. No profile of pro-inflammatory diets was identified among the patients with MS enrolled in this study.RESUMO Introdu ção: Esclerose múltipla (EM) é uma doença crônica e autoimune do sistema nervoso central. Ao longo do tempo, pacientes com EM acumulam incapacidades neurológicas. A EM tipicamente afeta adultos jovens e se associa a um perfil inflamatório de citocinas e linfócitos. Se um paciente tiver uma ...
Source: Arquivos de Neuro-Psiquiatria - November 2, 2020 Category: Neurology Source Type: research

Validation of the Brazilian Portuguese version of the Rapid Eye Movement Sleep Behavior Disorder Screening Questionnaire (RBDSQ-BR)
Conclusions: RBDSQ-BR is a reliable instrument, which may be useful for RBD diagnosis of Brazilian patients with PD. The instrument is also valid and may help in a better selection of cases for a more detailed clinical evaluation or even PSG analysis.RESUMO Introdu ção: O diagnóstico do transtorno comportamental do sono REM (TCSREM) implica na realização da polissonografia (PSG), mas sua disponibilidade pode não ser suficiente. Portanto, meios clínicos para o diagnóstico podem ser úteis. Objetivo: Validar para a língua portuguesa falada no Brasil o questionário de triagem do TCSREM (QT-TCSREM) em pacientes ...
Source: Arquivos de Neuro-Psiquiatria - November 2, 2020 Category: Neurology Source Type: research

Validation of 19-items wearing-off (WOQ-19) questionnaire to Portuguese
Conclusion: The Portuguese version of the WOQ-19 showed excellent diagnostic properties and can be used to diagnose wearing-off phenomena.RESUMO Introdu ção: O tratamento da doença de Parkinson com terapia dopaminérgica melhora a funcionalidade e a qualidade de vida. Entretanto, com a progressão da doença, os fenômenos de flutuação motora e não motora se desenvolvem. Para melhorar o reconhecimento dessa situação, foi desenvolvido o ques tionário de 19 itens de wearing-off (WOQ-19) Objetivo: Traduzir e validar o questionário WOQ-19 para a língua portuguesa. Métodos: O questionário foi traduzido do ing...
Source: Arquivos de Neuro-Psiquiatria - November 2, 2020 Category: Neurology Source Type: research

Electroacupuncture alleviates inflammatory pain via adenosine suppression and its mediated substance P expression
Conclusion: Our results indicate regulation of adenosine-mediated substance P secretion. Substance P-mediated pathway may be involved in the analgesia process by electroacupuncture in rats.RESUMO Introdu ção: A acupuntura tem sido amplamente utilizada para alívio de dor. No entanto, seus mecanismos são muito pouco conhecidos. Objetivo: Investigar a relação entre o efeito analgésico da eletroacupuntura e a regulação da expressão de adenosina e de substância P. Métodos: Utilizou-se um modelo de dor inflamatória crônica em ratos por injeção única do Adjuvante Completo de Freund e, em seguida, os anima...
Source: Arquivos de Neuro-Psiquiatria - November 2, 2020 Category: Neurology Source Type: research

Analysis of YouTube as a source of information for restless leg syndrome
Conclusions: This study demonstrates that 77% of the videos uploaded on YouTube regarding RLS are in the useful category, whereas only 16 videos were providing misleading information. However, even videos in the useful category do not provide a full and complete description of the RLS.RESUMO Introdu ção: O YouTube é um dos principais recursos no mundo para vídeos relacionados à saúde. Objetivo: O objetivo deste estudo foi avaliar a qualidade das informações disponíveis no YouTube sobre a síndrome das pernas inquietas (SPI). Métodos: Realizou-se uma busca no YouTube (https://www. youtube.com) para vídeos ...
Source: Arquivos de Neuro-Psiquiatria - November 2, 2020 Category: Neurology Source Type: research

Enriched environment alleviates post-stroke cognitive impairment through enhancing α7-nAChR expression in rats
Conclusions: EE markedly improves cognitive impairment and enhances neuroplasticity in PSCI rats, which may be closely related to enhancement of α 7-nAChR expression.RESUMO Introdu ção: O ambiente enriquecido (AE) é uma intervenção simples e eficaz para melhorar a função cognitiva no comprometimento cognitivo pós-AVC, em parte devido ao reequilíbrio da via de sinalização colinérgica no hipocampo. O receptor nicotínico α 7 de acetilcolina ( α 7-nAChR) é um receptor colinérgico cuja ativação inibe inflamação e promove a recuperação da função neurológica em pacientes com comprometimento cognitivo...
Source: Arquivos de Neuro-Psiquiatria - November 2, 2020 Category: Neurology Source Type: research

REM Behavior Disorder diagnostic challenges
(Source: Arquivos de Neuro-Psiquiatria)
Source: Arquivos de Neuro-Psiquiatria - November 2, 2020 Category: Neurology Source Type: research

Erratum: Association between executive and food functions in the acute phase after stroke
ABSTRACT Aloysio de Castro (1881-1959) is now remembered as one of Brazil's greatest physicians and is considered the father of Brazilian neurological semiology. However, his interests went far beyond the realm of Medicine, and he became one of the most illustrious intellectuals of his time. In 1927, he gave a speech at the S ão Paulo Society of Artistic Culture on Frédéric Chopin and embarked on a journey across the composer's life and times, discussing the medical issues involving his death, as well as his lovers, his compositions, and the spiritual aspects of musical interpretation. Thus, Castro reinforced the bond s...
Source: Arquivos de Neuro-Psiquiatria - October 7, 2020 Category: Neurology Source Type: research

Symptomatic female carriers of mutations in the Duchenne muscular dystrophy gene
ABSTRACT Aloysio de Castro (1881-1959) is now remembered as one of Brazil's greatest physicians and is considered the father of Brazilian neurological semiology. However, his interests went far beyond the realm of Medicine, and he became one of the most illustrious intellectuals of his time. In 1927, he gave a speech at the S ão Paulo Society of Artistic Culture on Frédéric Chopin and embarked on a journey across the composer's life and times, discussing the medical issues involving his death, as well as his lovers, his compositions, and the spiritual aspects of musical interpretation. Thus, Castro reinforced the bond s...
Source: Arquivos de Neuro-Psiquiatria - October 7, 2020 Category: Neurology Source Type: research

Migrainous periorbital ecchymosis
ABSTRACT Aloysio de Castro (1881-1959) is now remembered as one of Brazil's greatest physicians and is considered the father of Brazilian neurological semiology. However, his interests went far beyond the realm of Medicine, and he became one of the most illustrious intellectuals of his time. In 1927, he gave a speech at the S ão Paulo Society of Artistic Culture on Frédéric Chopin and embarked on a journey across the composer's life and times, discussing the medical issues involving his death, as well as his lovers, his compositions, and the spiritual aspects of musical interpretation. Thus, Castro reinforced the bond s...
Source: Arquivos de Neuro-Psiquiatria - October 7, 2020 Category: Neurology Source Type: research

STIR and diffusion-weighted MRI in asymptomatic hyperCKemia caused by ANO5-related myopathy
ABSTRACT Aloysio de Castro (1881-1959) is now remembered as one of Brazil's greatest physicians and is considered the father of Brazilian neurological semiology. However, his interests went far beyond the realm of Medicine, and he became one of the most illustrious intellectuals of his time. In 1927, he gave a speech at the S ão Paulo Society of Artistic Culture on Frédéric Chopin and embarked on a journey across the composer's life and times, discussing the medical issues involving his death, as well as his lovers, his compositions, and the spiritual aspects of musical interpretation. Thus, Castro reinforced the bond s...
Source: Arquivos de Neuro-Psiquiatria - October 7, 2020 Category: Neurology Source Type: research

“…In the immortal forms of beauty”: Frédéric Chopin seen through the eyes of the father of Brazilian neurological semiology
ABSTRACT Aloysio de Castro (1881-1959) is now remembered as one of Brazil's greatest physicians and is considered the father of Brazilian neurological semiology. However, his interests went far beyond the realm of Medicine, and he became one of the most illustrious intellectuals of his time. In 1927, he gave a speech at the S ão Paulo Society of Artistic Culture on Frédéric Chopin and embarked on a journey across the composer's life and times, discussing the medical issues involving his death, as well as his lovers, his compositions, and the spiritual aspects of musical interpretation. Thus, Castro reinforced the bond s...
Source: Arquivos de Neuro-Psiquiatria - October 7, 2020 Category: Neurology Source Type: research

Deep brain stimulation treatment in dystonia: a bibliometric analysis
Conclusions: DBS in dystonia research is mainly published in a handful of scientific journals and focused on the outcomes of the surgery in idiopathic or inherited, isolated, segmental or generalized dystonia, and with globus pallidus internus as the main DBS target.RESUMO Introdu ção: A distonia é uma doença heterogênea que, quando refratária ao tratamento medicamentoso, pode ter uma resposta favorável à estimulação encefálica profunda (EEP). Uma forma prática de ter uma visão desta área de pesquisa é por meio de análise bibliométrica, pois permite aos pesq uisadores e terceiros a terem uma ideia das t...
Source: Arquivos de Neuro-Psiquiatria - October 7, 2020 Category: Neurology Source Type: research

Evidence and practices of the use of next generation sequencing in patients with undiagnosed autosomal dominant cerebellar ataxias: a review
ABSTRACT Autosomal dominant cerebellar ataxias (ADCA) are heterogeneous diseases with a highly variable phenotype and genotype. They can be divided into episodic ataxia and spinocerebellar ataxia (SCA); the latter is considered the prototype of the ADCA. Most of the ADCA are caused by polyglutamine expansions, mainly SCA 1, 2, 3, 6, 7, 17 and Dentatorubral-pallidoluysian atrophy (DRPLA). However, 30% of patients remain undiagnosed after testing for these most common SCA. Recently, several studies have demonstrated that the new generation of sequencing methods are useful for the diagnose of these patients. This review focus...
Source: Arquivos de Neuro-Psiquiatria - October 7, 2020 Category: Neurology Source Type: research