Pancreaticoduodenectomy with venous resection: an analysis of 30-day morbidity and mortality
CONCLUSION: PD with venous resection for advanced pancreatic neoplasms is a feasible procedure, but associated with high rates of morbidity and mortality; higher ASA e ECOG scores were significantly associated with a higher 30-day mortality.RESUMO CONTEXTO: A duodenopancreatectomia (DP) com ressec ção de estruturas venosas adjacentes à cabeça do pâncreas, mesmo em casos de invasão extensa, tem sido praticada nos últimos anos, mas sua morbidade e mortalidade perioperatórias não são completamente determinadas. OBJETIVO: Descrever os resultados perioperatórios de DP com ressecções venosas realizadas em um h...
Source: Arquivos de Gastroenterologia - September 30, 2019 Category: Gastroenterology Source Type: research
Nonalcoholic fatty liver disease (nafld), more than a liver disease
(Source: Arquivos de Gastroenterologia)
Source: Arquivos de Gastroenterologia - September 30, 2019 Category: Gastroenterology Source Type: research
Update of the brazilian society of hepatology recommendations for diagnosis and management of autoimmune diseases of the liver
ABSTRACT New data concerning the management of autoimmune liver diseases have emerged since the last single-topic meeting sponsored by the Brazilian Society of Hepatology to draw recommendations about the diagnosis and treatment of autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC), overlap syndromes of AIH, PBC and PSC and specific complications and topics concerning AIH and cholestatic liver diseases. This manuscript updates those previous recommendations according to the best evidence available in the literature up to now. The same panel of experts that took part in the f...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research
Recommendations for invasive procedures in patients with diseases of the liver and biliary tract: report of a joint meeting of the brazilian society of hepatology (sbh), brazilian society of digestive endoscopy (sobed) and brazilian society of interventional radiology and endovascular surgery (sobrice)
ABSTRACT Liver and biliary tract diseases are common causes of morbidity and mortality worldwide. Invasive procedures are usually performed in those patients with hepatobiliary diseases for both diagnostic and therapeutic purposes. Defining proper indications and restraints of commonly used techniques is crucial for proper patient selection, maximizing positive results and limiting complications. In 2018, the Brazilian Society of Hepato logy (SBH) in cooperation with the Brazilian Society of Interventional Radiology and Endovascular surgery (SOBRICE) and the Brazilian Society of Digestive Endoscopy (SOBED) sponsored a jo...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research
In defense of four decades of esophageal function tests. reply to reaction to articles on high resolution manometry, the length of the lower esophageal sphincter and the diagnosis of gastroesophageal reflux disease
CONCLUSION: Recognizing the historical evolution of GERD management can help care providers to better understand therapeutic options for their patients, as well as focus on unmet needs that deserve further attention. PPIs are still the first choice therapy, with good evidence in favor of their efficacy, despite some safety concerns. However, as with any medical intervention, it is recommended to prescribe PPIs for patients with clear indication, using adequate dosing and monitoring for adverse events.RESUMO CONTEXTO: A doen ça do refluxo gastroesofágico (DRGE) é uma das doenças gastrointestinais mais prevalentes, re...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research
Reaction to articles on high resolution manometry, the length of the lower esophageal sphincter and the diagnosis of gastroesophageal reflux disease
CONCLUSION: Recognizing the historical evolution of GERD management can help care providers to better understand therapeutic options for their patients, as well as focus on unmet needs that deserve further attention. PPIs are still the first choice therapy, with good evidence in favor of their efficacy, despite some safety concerns. However, as with any medical intervention, it is recommended to prescribe PPIs for patients with clear indication, using adequate dosing and monitoring for adverse events.RESUMO CONTEXTO: A doen ça do refluxo gastroesofágico (DRGE) é uma das doenças gastrointestinais mais prevalentes, re...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research
Historical perspective of gastroesophageal reflux disease clinical treatment
CONCLUSION: Recognizing the historical evolution of GERD management can help care providers to better understand therapeutic options for their patients, as well as focus on unmet needs that deserve further attention. PPIs are still the first choice therapy, with good evidence in favor of their efficacy, despite some safety concerns. However, as with any medical intervention, it is recommended to prescribe PPIs for patients with clear indication, using adequate dosing and monitoring for adverse events.RESUMO CONTEXTO: A doen ça do refluxo gastroesofágico (DRGE) é uma das doenças gastrointestinais mais prevalentes, re...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research
Prospective study for validation of a single protocol for the 13c-urea breath test using two different devices in the diagnosis of h. pylori infection
CONCLUSION: Correlation between the two devices was excellent and supports a uniform standardization of UBT.RESUMO CONTEXTO: O teste respirat ório com ureia-marcada com carbono-13 (TR-13C) é o método padrão-ouro para o diagnóstico não invasivo da infecção por H. pylori. Apesar disto, não existe uma uniformização de protocolos para a sua realização, trazendo dificuldades operacionais para laboratórios ou clínicas que operam com equipamentos de fabricantes diferentes. OBJETIVO: Estudo prospectivo e comparativo para validação do TR-13C para o diagnóstico de infecção por H. pylori, com emprego de protoc...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research
Morphological characterization of colorectal pits using autofluorescence microscopy images
CONCLUSION: These preliminaries outcomes could be considered an advance in two-dimensional pit characterization as the whole image processing, comparing to the conventional procedure, takes a few seconds to quantify and charact erize non-pathological colon pits as well as to estimate early pathological stages of colorectal cancer.RESUMO CONTEXTO: O c âncer colorretal é uma das patologias mais prevalentes. Seu prognóstico é ligado à detenção e ao tratamento precoces. Atualmente o diagnóstico é realizado por análise histológica de biópsias de pólipo, seguida de classificação morfológica. A classificação ...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research
N-acetylcysteine and/or ursodeoxycholic acid associated with metformin in non-alcoholic steatohepatitis: an open-label multicenter randomized controlled trial
CONCLUSION: This multicenter study suggests that the association of NAC + MTF could reduce the liver disease activity in patients wi th NASH. These data stimulate further controlled studies with this therapy for these patients.RESUMO CONTEXTO: Atualmente, o tratamento farmacol ógico da doença hepática gordurosa não alcoólica (DHGNA) ainda é limitado e baseia-se no tratamento de condições associadas às comorbidades. O estresse oxidativo e a resistência à insulina são os mecanismos que parecem estar mais envolvidos em sua patogênese. OBJETIVO: Avaliar a eficá cia da N-acetilcisteína (NAC) em associação ...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research
Clinical profile, drug resistance pattern and treatment outcomes of abdominal tuberculosis patients in western india
CONCLUSION: Abdominal tuberculosis with wide spectrum of presentation, can still be managed with early diagnosis and treatment even in patients with sub acute intestinal obstruction. Weight gain or resolving symptoms were considered early markers of treatment response. Patients with stricture can become asymptomatic with medical treatment alone.RESUMO CONTEXTO: A tuberculose abdominal é um problema crescente no mundo em desenvolvimento. OBJETIVO: O objetivo do estudo foi descrever as apresentações clínicas, o padrão de resistência a fármacos e os desfechos de tratamento da tuberculose abdominal na Índia ociden...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research
Adiponectin, vitamin d and nutritional status in patients with advanced colorectal cancer or during follow-up
CONCLUSION: Among the nutritional status parameters, only the Patient-Generated Subjective Global Assessment score was significantly different between the groups and was an important predictor of survival in patients with advanced colorectal cancer.RESUMO CONTEXTO: Considerando a alta incid ência de óbitos devido ao câncer coloretal (CCR), estudos investigaram variáveis que podem afetar a sobrevida, com objetivo de prolongar a sobrevida. O estado nutricional desses pacientes também pode predizer a sobrevida. OBJETIVO: O objetivo do presente estudo foi avaliar se o índice de mas sa corporal (IMC), a porcentagem d...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research
The cost of adult liver transplantation in a referral center in southern brazil
CONCLUSION: Our results demonstrated that the total cost of LTx is closely related to liver disease severity scores and the development of complications.RESUMO CONTEXTO: O transplante hep ático (TxH) é o principal e definitivo tratamento de casos agudos ou crônicos de doenças hepáticas avançadas ou terminais. Poucos estudos têm avaliado o custo real do TxH categorizado por setores hospitalares. OBJETIVO: Avaliar o custo do TxH categorizado por especialidade da unidade em um centro de referência na região sul do Brasil. MÉTODOS: Analisamos retrospectivamente os prontuários de 109 pacientes submetidos a TxH...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research
Internal hernia following laparoscopic roux-en-y gastric by-pass: indicative factors for early repair
CONCLUSION: The presence of recurrent abdominal pain is one of the main indicators for the diagnosis of IH after LRYGB. Patients operated at an early stage, even with negative imaging tests for this disease, benefited from rapid and simple procedures without major complications.RESUMO CONTEXTO: H érnia interna (HI) após bypass gástrico em Y de Roux laparoscópico (BGYRL) é uma complicação importante que desafia o cirurgião devido à sua apresentação inespecífica e necessidade de reparo precoce. Um diagnóstico e intervenção cirúrgica tardios para HI pode levar a um aumento na mo rbidade dos pacientes e traz...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research
Cytotoxic effects of aripiprazole on mkn45 and nih3t3 cell lines and genotoxic effects on human peripheral blood lymphocytes
CONCLUSION: Aripiprazole can be a good cytotoxic compound and good candidate for further studies of cancer therapy.RESUMO CONTEXTO: O c âncer gástrico é conhecido como o quarto câncer mais comum. Os tratamentos atuais para o câncer danificaram os tecidos sensíveis do corpo saudável e, em muitos casos, o cancro será recorrente. Portanto, a necessidade de tratamentos que são mais eficazes é desejada. Recentemente, os pesquis adores mudaram sua atenção para os antagonistas antipsicóticos da dopamina para tratar o câncer. As atividades anticâncer de aripiprazol permanecem desconhecidas. OBJETIVO: Este estud...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research
